2CDN

Crystal structure of Mycobacterium tuberculosis adenylate kinase complexed with two molecules of ADP and Mg

Summary for 2CDN

• Entry DOI: 10.2210/pdb2cdn/pdb
• Related: 1P4S
• Descriptor: ADENYLATE KINASE, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: adenylate kinase, phosphoryl transfer, associative mechanism, atp-binding, kinase, nucleotide biosynthesis, nucleotide-binding, transferase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Cellular location: Cytoplasm: P69440
• Total number of polymer chains: 1
• Total formula weight: 23202.98

Authors

Bellinzoni, M.,Haouz, A.,Grana, M.,Munier-Lehmann, H.,Alzari, P.M. (deposition date: 2006-01-25, release date: 2006-05-10, Last modification date: 2023-12-13)

• Primary citation: Bellinzoni, M.,Haouz, A.,Grana, M.,Munier-Lehmann, H.,Shepard, W.,Alzari, P.M.; The Crystal Structure of Mycobacterium Tuberculosis Adenylate Kinase in Complex with Two Molecules of Adp and Mg2+ Supports an Associative Mechanism for Phosphoryl Transfer.; Protein Sci., 15:1489-, 2006; PubMed: 16672241; DOI: 10.1110/PS.062163406

Experimental method

X-RAY DIFFRACTION (1.9 Å)