1JD9
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6QDX
| Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA4) | 分子名称: | (2~{S})-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{S},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid, Ribosomal RNA large subunit methyltransferase J | 著者 | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | 登録日 | 2019-01-03 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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1JDN
| Crystal Structure of Hormone Receptor | 分子名称: | ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, CHLORIDE ION, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | He, X.-L, Chow, D.-C, Martick, M.M, Garcia, K.C. | 登録日 | 2001-06-14 | 公開日 | 2001-09-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone. Science, 293, 2001
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6QEH
| CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR 5-Chloro-quinolin-8-ol | 分子名称: | 5-chloranylquinolin-8-ol, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Musil, D, Heinrich, T, Lehmann, M. | 登録日 | 2019-01-07 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase-2 (MetAP-2) Inhibitors. J.Med.Chem., 62, 2019
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7TBY
| The structure of human ABCA1 in nanodisc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | 著者 | Sun, Y, Li, X. | 登録日 | 2021-12-22 | 公開日 | 2022-01-26 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nat Cardiovasc Res, 1, 2022
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1JDZ
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE WITH FORMYCIN B AND SULFATE ION | 分子名称: | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, FORMYCIN B, SULFATE ION | 著者 | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | 登録日 | 2001-06-15 | 公開日 | 2001-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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7SSM
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6QCI
| Structure of XIAP-BIR1 V86E mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... | 著者 | Sorrentino, L, Cossu, F, Milani, M, Mastrangelo, E. | 登録日 | 2018-12-28 | 公開日 | 2019-05-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1. Chemistryopen, 8, 2019
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7T54
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6QCK
| 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262 | 分子名称: | 17-beta-hydroxysteroid dehydrogenase 14, 2-[2-(1,3-benzodioxol-2-yl)ethyl]benzoic acid, DIMETHYL SULFOXIDE, ... | 著者 | Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. | 登録日 | 2018-12-28 | 公開日 | 2020-01-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Mutational and structural studies uncover crucial amino acids determining activity and stability of 17 beta-HSD14. J.Steroid Biochem.Mol.Biol., 189, 2019
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1JDR
| Crystal Structure of a Proximal Domain Potassium Binding Variant of Cytochrome c Peroxidase | 分子名称: | Cytochrome c Peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bonagura, C.A, Sundaramoorthy, M, Bhaskar, B, Poulos, T.L. | 登録日 | 2001-06-14 | 公開日 | 2001-06-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The effects of an engineered cation site on the structure, activity, and EPR properties of cytochrome c peroxidase. Biochemistry, 38, 1999
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1JE0
| CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH PHOSPHATE AND TRIS MOLECULE | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-METHYLTHIOADENOSINE PHOSPHORYLASE, PHOSPHATE ION | 著者 | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | 登録日 | 2001-06-15 | 公開日 | 2001-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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7SZL
| Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1R10 (IL-1RAPL2) | 分子名称: | X-linked interleukin-1 receptor accessory protein-like 2 | 著者 | Nimma, S, Gu, W, Manik, M.K, Ve, T, Nanson, J.D, Kobe, B. | 登録日 | 2021-11-28 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of IL-1R10 provides structural insights into TIR domain signalling. Febs Lett., 596, 2022
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6QCM
| Cryo em structure of the Listeria stressosome | 分子名称: | RsbR protein, RsbR protein,RsbR protein, RsbS protein | 著者 | Williams, A.H, Redzej, A, Waksman, G, Cossart, P. | 登録日 | 2018-12-28 | 公開日 | 2019-08-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.21 Å) | 主引用文献 | The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nat Commun, 10, 2019
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1JEH
| CRYSTAL STRUCTURE OF YEAST E3, LIPOAMIDE DEHYDROGENASE | 分子名称: | DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Toyoda, T, Suzuki, K, Sekigushi, T, Reed, J, Takenaka, A. | 登録日 | 2001-06-18 | 公開日 | 2001-07-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of eucaryotic E3, lipoamide dehydrogenase from yeast. J.Biochem., 123, 1998
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7T7X
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6QD1
| MloK1 model from single particle analysis of 2D crystals, class 5 (intermediate compact conformation) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | 登録日 | 2018-12-31 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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1JEY
| Crystal Structure of the Ku heterodimer bound to DNA | 分子名称: | DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), Ku70, ... | 著者 | Walker, J.R, Corpina, R.A, Goldberg, J. | 登録日 | 2001-06-19 | 公開日 | 2001-08-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature, 412, 2001
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6QER
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7TDF
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7SQ6
| Cryo-EM structure of mouse agonist ML-SA1-bound TRPML1 channel at 2.32 Angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1, ... | 著者 | Gan, N, Han, Y, Jiang, Y. | 登録日 | 2021-11-04 | 公開日 | 2022-02-02 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | 主引用文献 | Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P 2 and rapamycin. Proc.Natl.Acad.Sci.USA, 119, 2022
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1JFI
| Crystal Structure of the NC2-TBP-DNA Ternary Complex | 分子名称: | 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ... | 著者 | Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2001-06-20 | 公開日 | 2001-07-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell(Cambridge,Mass.), 106, 2001
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6QF6
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7T7S
| R-27 in Complex with S. aureus DHFR and tricyclic-NADPH (tNADPH) | 分子名称: | 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, ACETATE ION, Dihydrofolate reductase, ... | 著者 | Reeve, S.M, Wang, S, Donald, B.R, Wright, D.L. | 登録日 | 2021-12-15 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus. Plos Comput.Biol., 18, 2022
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6QFD
| The complex structure of hsRosR-S4 (vng0258/RosR-S4) | 分子名称: | DNA (28-MER), DNA-binding protein, MANGANESE (II) ION, ... | 著者 | Shaanan, B, Kutnowski, N. | 登録日 | 2019-01-10 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.133 Å) | 主引用文献 | Specificity of protein-DNA interactions in hypersaline environment: structural studies on complexes of Halobacterium salinarum oxidative stress-dependent protein hsRosR. Nucleic Acids Res., 47, 2019
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