4NC2
 
 | | Crystal structure of TcdB-B1 bound to B39 VHH | | 分子名称: | B39 VHH, Toxin B | | 著者 | Murase, T, Eugenio, L, Schorr, M, Hussack, G, Tanha, J, Kitova, E.N, Klassen, J.S, Ng, K.K.S. | | 登録日 | 2013-10-23 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
J.Biol.Chem., 289, 2014
|
|
4NC3
 | | Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHOLESTEROL, ... | | 著者 | Liu, W, Wacker, D, Gati, C, Han, G.W, James, D, Wang, D, Nelson, G, Weierstall, U, Katritch, V, Barty, A, Zatsepin, N.A, Li, D, Messerschmidt, M, Boutet, S, Williams, G.J, Koglin, J.E, Seibert, M.M, Wang, C, Shah, S.T.A, Basu, S, Fromme, R, Kupitz, C, Rendek, K.N, Grotjohann, I, Fromme, P, Kirian, R.A, Beyerlein, K.R, White, T.A, Chapman, H.N, Caffrey, M, Spence, J.C.H, Stevens, R.C, Cherezov, V, GPCR Network (GPCR) | | 登録日 | 2013-10-23 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Serial femtosecond crystallography of G protein-coupled receptors.
Science, 342, 2013
|
|
4NC4
 | | Crystal structure of photoreceptor AtUVR8 mutant W285F and light-induced structural changes at 120K | | 分子名称: | MAGNESIUM ION, Ultraviolet-B receptor UVR8 | | 著者 | Yang, X, Zeng, X, Zhao, K.-H, Ren, Z. | | 登録日 | 2013-10-23 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
|
|
4NC5
 | | Human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate) | | 分子名称: | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, PHOSPHATE ION, Sialidase-2 | | 著者 | Buchini, S, Gallat, F.-X, Greig, I.R, Kim, J.-H, Wakatsuki, S, Chavas, L.M.G, Withers, S.G. | | 登録日 | 2013-10-24 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.513 Å) | | 主引用文献 | Tuning mechanism-based inactivators of neuraminidases: mechanistic and structural insights.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4NC6
 | |
4NC7
 | | N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | | 著者 | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
|
|
4NC8
 | | N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions | | 分子名称: | DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | | 著者 | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
|
|
4NC9
 | | Crystal structure of phosphatidyl mannosyltransferase PimA | | 分子名称: | GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase | | 著者 | Giganti, D, Albesa-Jove, D, Bellinzoni, M, Guerin, M.E, Alzari, P.M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | | 主引用文献 | Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat.Chem.Biol., 11, 2015
|
|
4NCA
 | | Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+ | | 分子名称: | 5'-D(*AP*CP*AP*AP*CP*C)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', ... | | 著者 | Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y. | | 登録日 | 2013-10-24 | | 公開日 | 2014-01-15 | | 最終更新日 | 2025-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | | 主引用文献 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4NCB
 | | Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+ | | 分子名称: | 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3', 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', ... | | 著者 | Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y. | | 登録日 | 2013-10-24 | | 公開日 | 2014-01-15 | | 最終更新日 | 2025-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4NCC
 | | Neutralizing antibody to murine norovirus | | 分子名称: | Fab fragment heavy, Fab fragment light | | 著者 | Smith, T, Li, M. | | 登録日 | 2013-10-24 | | 公開日 | 2014-02-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.
J.Virol., 88, 2014
|
|
4NCD
 | | Crystal Structure of Class 5 Fimbriae Chaperone CfaA | | 分子名称: | Gram-negative pili assembly chaperone, N-terminal domain protein | | 著者 | Bao, R, Xia, D. | | 登録日 | 2013-10-24 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.037 Å) | | 主引用文献 | Structure of CfaA Suggests a New Family of Chaperones Essential for Assembly of Class 5 Fimbriae.
Plos Pathog., 10, 2014
|
|
4NCE
 | | Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid, Polymerase basic protein 2 | | 著者 | Jacobs, M.D. | | 登録日 | 2013-10-24 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2.
J.Med.Chem., 57, 2014
|
|
4NCF
 | |
4NCG
 | | Discovery of Doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses | | 分子名称: | 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile, Reverse transcriptase/ribonuclease H, p51 RT | | 著者 | Yan, Y. | | 登録日 | 2013-10-24 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Bioorg.Med.Chem.Lett., 24, 2014
|
|
4NCH
 | | Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation | | 分子名称: | DNA double-strand break repair Rad50 ATPase, SULFATE ION | | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | | 登録日 | 2013-10-24 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
|
|
4NCI
 | | Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation | | 分子名称: | DNA double-strand break repair Rad50 ATPase | | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | | 登録日 | 2013-10-24 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
|
|
4NCJ
 | | Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA double-strand break repair Rad50 ATPase, ... | | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | | 登録日 | 2013-10-24 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
|
|
4NCK
 | | Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation | | 分子名称: | CHLORIDE ION, DNA double-strand break repair Rad50 ATPase, MAGNESIUM ION, ... | | 著者 | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | | 登録日 | 2013-10-24 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
|
|
4NCL
 | |
4NCM
 | |
4NCN
 | |
4NCO
 | | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ... | | 著者 | Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A. | | 登録日 | 2013-10-24 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | | 主引用文献 | Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
|
|
4NCP
 | |
4NCQ
 | |
