4NCN
Crystal structure of eukaryotic translation initiation factor eIF5B (517-858) from Chaetomium thermophilum in complex with GTP
Summary for 4NCN
| Entry DOI | 10.2210/pdb4ncn/pdb |
| Related | 4NCF 4NCL |
| Descriptor | Eukaryotic translation initiation factor 5B-like protein, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | translation initiation, gtpase, eif5b/if2, subunit joining, ribosome, translation |
| Biological source | Chaetomium thermophilum var. thermophilum |
| Cellular location | Cytoplasm : G0S8G9 |
| Total number of polymer chains | 2 |
| Total formula weight | 103790.68 |
| Authors | Kuhle, B.,Ficner, R. (deposition date: 2013-10-24, release date: 2014-07-09, Last modification date: 2023-09-20) |
| Primary citation | Kuhle, B.,Ficner, R. eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining. Embo J., 33:1177-1191, 2014 Cited by PubMed: 24686316DOI: 10.1002/embj.201387344 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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