8VFG
| Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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6RMR
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9BKK
| Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex | 分子名称: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Harikumar, K.G, Zhao, P, Cary, B.P, Xu, X, Desai, A.J, Mobbs, J.I, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J. | 登録日 | 2024-04-29 | 公開日 | 2024-05-22 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling. Plos Biol., 22, 2024
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9BRS
| Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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8VFD
| Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog | 分子名称: | 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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9FST
| Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | 登録日 | 2024-06-21 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites To Be Published
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6RO2
| The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor | 分子名称: | 2-sulfanyl-1,9-dihydro-6H-purin-6-one, DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), ... | 著者 | Coste, F, Goffinont, S, Castaing, B. | 登録日 | 2019-05-10 | 公開日 | 2020-04-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.821 Å) | 主引用文献 | Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. Int J Mol Sci, 21, 2020
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9BRA
| Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRR
| Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9FT1
| Yeast 20S proteasome in complex with epoxyketone inhibitor 13 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | 著者 | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | 登録日 | 2024-06-23 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites to be published
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8W1Q
| Aerobic crystal structure of iron-bound FlcD from Pseudomonas aeruginosa | 分子名称: | FE (II) ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Walker, M.E, Grove, T.L, Li, B, Redinbo, M.R. | 登録日 | 2024-02-17 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural Basis for Methine Excision by a Heme Oxygenase-like Enzyme Acs Cent.Sci., 2024
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4WE3
| STRUCTURE OF THE BINARY COMPLEX OF A ZINGIBER OFFICINALE DOUBLE BOND REDUCTASE IN COMPLEX WITH NADP MONOCLINIC CRYSTAL FORM | 分子名称: | Double Bond Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Collery, J, Langlois d'Estaintot, B, Buratto, J, Granier, T, Gallois, B, Willis, M.A, Sang, Y, Flores-Sanchez, I.J, Gang, D.R. | 登録日 | 2014-09-09 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | STRUCTURE OF ZINGIBER OFFICINALE DOUBLE BOND REDUCTASE to be published
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8EQ8
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6TYS
| A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ... | 著者 | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-08-09 | 公開日 | 2019-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
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6TZ7
| Crystal Structure of Aspergillus fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | 分子名称: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | 著者 | Fox III, D, Horanyi, P.S. | 登録日 | 2019-08-10 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
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6TZR
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8SWV
| BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody IF1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IF1 Heavy Chain, ... | 著者 | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | 登録日 | 2023-05-19 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Priming antibody responses to the fusion peptide in rhesus macaques. Npj Vaccines, 9, 2024
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7RU3
| CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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6U6Z
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7Q4M
| Type II beta-amyloid 42 Filaments from Human Brain | 分子名称: | Amyloid-beta precursor protein, UNKNOWN ATOM OR ION | 著者 | Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M. | 登録日 | 2021-11-01 | 公開日 | 2021-11-24 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta 42 filaments from human brains. Science, 375, 2022
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7Q4B
| Type I beta-amyloid 42 Filaments from Human Brain | 分子名称: | Amyloid-beta precursor protein, UNKNOWN ATOM OR ION | 著者 | Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M. | 登録日 | 2021-10-30 | 公開日 | 2021-11-24 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Cryo-EM structures of amyloid-beta 42 filaments from human brains. Science, 375, 2022
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5HFK
| CRYSTAL STRUCTURE OF A GLUTATHIONE S-TRANSFERASE PROTEIN FROM ESCHERICHIA COLI OCh 157:H7 STR. SAKAI (ECs3186, TARGET EFI-507414) WITH BOUND GLUTATHIONE | 分子名称: | Disulfide-bond oxidoreductase YfcG, GLUTATHIONE | 著者 | Himmel, D.M, Toro, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI), New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2016-01-07 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | CRYSTAL STRUCTURE OF A GLUTATHIONE S-TRANSFERASE PROTEIN FROM ESCHERICHIA COLI OCh 157:H7 STR. SAKAI (ECs3186, TARGET EFI-507414) WITH BOUND GLUTATHIONE TO BE PUBLISHED
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7S4E
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8EQQ
| Crystal structure of E.coli DsbA mutant E37A | 分子名称: | CITRATE ANION, Thiol:disulfide interchange protein DsbA | 著者 | Wang, G, Heras, B. | 登録日 | 2022-10-09 | 公開日 | 2023-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
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7SE2
| [C:Ag+:mC] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*(5CM)P*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | 著者 | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | 登録日 | 2021-09-29 | 公開日 | 2022-10-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.03 Å) | 主引用文献 | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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