9FT1

Yeast 20S proteasome in complex with epoxyketone inhibitor 13

This is a non-PDB format compatible entry.

Summary for 9FT1

• Entry DOI: 10.2210/pdb9ft1/pdb
• Related: 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total)
• Functional Keywords: yeast 20s proteasome in complex with epoxyketone inhibitor 13, hydrolase
• Biological source: Saccharomyces cerevisiae (brewer's yeast); More
• Total number of polymer chains: 28
• Total formula weight: 735373.05

Authors

Maurits, E.,Huber, E.M.,Dekker, P.M.,Wang, X.,Heinemeyer, W.,Florea, B.I.,Groll, M.,Overkleeft, H.S. (deposition date: 2024-06-23, release date: 2024-07-10, Last modification date: 2024-11-13)

• Primary citation: Maurits, E.,Huber, E.M.,Dekker, P.M.,Wang, X.,Heinemeyer, W.,Florea, B.I.,Groll, M.,Overkleeft, H.S.; Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites; to be published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)