9FT1
Yeast 20S proteasome in complex with epoxyketone inhibitor 13
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 2 | B, P | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 3 | C, Q | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 4 | D, R | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 5 | E, S | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF00227) Pfam (PF10584) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 6 | F, T | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 7 | G, U | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 8 | H, V | Proteasome subunit beta type-2 | polymer | 231 | 25013.4 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
| 9 | I, W | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
| 10 | J, X | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
| 11 | K, Y | Proteasome subunit beta type-5 | polymer | 211 | 23224.1 | 2 | UniProt (P30656) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
| 12 | L, Z | Proteasome subunit beta type-6 | polymer | 222 | 24883.9 | 2 | UniProt (P23724) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
| 13 | M, a | Proteasome subunit beta type-7 | polymer | 246 | 27200.9 | 2 | UniProt (P30657) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 14 | N, b | Proteasome subunit beta type-1 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 15 | G, H, I, K, N... | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 16 | H, J, V, X, b | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 5 | Chemie (MES) | |||
| 17 | H, K, V, Y | tert-butyl 4-[2-[[(2S)-1-[[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-3-phenylmethoxy-propan-2-yl]amino]-2-oxidanylidene-ethyl]piperazine-1-carboxylate | non-polymer | 895.1 | 4 | Chemie (A1IFK) | synthetic construct | ||
| 18 | water | water | 18.0 | 379 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 730646.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 4726.7 | |
| All* | Total formula weight | 735373.0 |
