PDB: 1008 件ウェブページステータス検索Chemie searchBIRD

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7G1H	Crystal Structure of human FABP4 in complex with 2-(3,5-ditert-butyl-2-hydroxyphenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid 分子名称: (2R)-2-(3,5-di-tert-butyl-2-hydroxyphenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid, FORMIC ACID, Fatty acid-binding protein, ... 著者 Ehler, A, Benz, J, Obst, U, Masciadri, R, Rudolph, M.G. 登録日 2023-04-27 公開日 2023-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Crystal Structure of a human FABP4 complex To be published
7G1M	Crystal Structure of human FABP4 binding site mutated to that of FABP5 in complex with rac-(1R,2R)-2-[[3-(3-methyl-1,2,4-oxadiazol-5-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl]cyclohexane-1-carboxylic acid 分子名称: (1R,2S)-2-{[(3M)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, Fatty acid-binding protein, adipocyte 著者 Ehler, A, Benz, J, Obst, U, Neidhart, W, Rudolph, M.G. 登録日 2023-04-27 公開日 2023-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Crystal Structure of a human FABP4 binding site mutated to that of FABP5 complex To be published
7G1Q	Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid 分子名称: (1R,2S)-2-{[5-carbamoyl-3-(ethoxycarbonyl)-4-methylthiophen-2-yl]carbamoyl}cyclohexane-1-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein 5, ... 著者 Ehler, A, Benz, J, Obst, U, Rudolph, M.G. 登録日 2023-04-27 公開日 2023-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Crystal Structure of a human FABP5 complex To be published
7G1Y	Crystal Structure of human FABP4 in complex with 2-[(3-methoxyphenyl)sulfanylmethyl]-1,3-thiazole-4-carboxylic acid 分子名称: 2-{[(3-methoxyphenyl)sulfanyl]methyl}-1,3-thiazole-4-carboxylic acid, FORMIC ACID, Fatty acid-binding protein, ... 著者 Ehler, A, Benz, J, Obst, U, Grenz-Achim, K, Rudolph, M.G. 登録日 2023-04-27 公開日 2023-06-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Crystal Structure of a human FABP4 complex To be published
7KOT	Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin 分子名称: Beta-lactoglobulin, DODECYL SULFATE 著者 Rodriguez-Hernandez, A, Rodriguez-Romero, A. 登録日 2020-11-09 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Energetic and structural effects of the Tanford transition on ligand recognition of bovine beta-lactoglobulin. Arch.Biochem.Biophys., 699, 2021
7LHJ	Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal 分子名称: ACETATE ION, GLYCEROL, RETINAL, ... 著者 Ehyaei, N, Geiger, J.H, Borhan, B. 登録日 2021-01-25 公開日 2021-02-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15cis- retinal To Be Published
7LHN	Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light 分子名称: GLYCEROL, RETINAL, Retinol-binding protein 2 著者 Ehyaei, N, Geiger, J.H, Borhan, B. 登録日 2021-01-25 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light To Be Published
7LHM	Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal 分子名称: ACETATE ION, GLYCEROL, RETINAL, ... 著者 Ehyaei, N, Geiger, J.H, Borhan, B. 登録日 2021-01-25 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal To Be Published
7LHO	Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark 分子名称: GLYCEROL, RETINAL, Retinol-binding protein 2 著者 Ehyaei, N, Geiger, J.H, Borhan, B. 登録日 2021-01-26 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark To Be Published
7LWC	Goat beta-lactoglobulin mutant Q59A 分子名称: Beta-lactoglobulin 著者 Munoz, D.A, Dobson, R.C.J. 登録日 2021-02-28 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Engineering food proteins for improved digestibility and lower allergenicity: a case study using caprine beta-lactoglobulin To Be Published
6QBA	Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with non-retinoid ligand A1120 and engineered binding scaffold 分子名称: 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Mlynek, G, Brey, C.U, Djinovic-Carugo, K, Puehringer, D. 登録日 2018-12-20 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A conformation-specific ON-switch for controlling CAR T cells with an orally available drug. Proc.Natl.Acad.Sci.USA, 117, 2020
2WQA	Complex of TTR and RBP4 and Oleic Acid 分子名称: OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ... 著者 Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J. 登録日 2009-08-14 公開日 2010-09-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr To be Published
6SUA	Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain 分子名称: 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin, SULFATE ION 著者 Schiefner, A, Deuschle, F.-C, Skerra, A. 登録日 2019-09-13 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice. Protein Sci., 29, 2020
6S8V	Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain 分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin 著者 Schiefner, A, Deuschle, F.-C, Skerra, A. 登録日 2019-07-10 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications. Theranostics, 10, 2020
4QAE	Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ... 著者 Giese, T, Skerra, A. 登録日 2014-05-04 公開日 2015-05-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of a hepcidin-binding anticalin in complex with its peptide ligand To be Published
1QAB	The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP 分子名称: PROTEIN (retinol binding protein), PROTEIN (transthyretin), RETINOL 著者 Naylor, H.M, Newcomer, M.E. 登録日 1999-02-03 公開日 1999-02-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP. Biochemistry, 38, 1999
1RLB	RETINOL BINDING PROTEIN COMPLEXED WITH TRANSTHYRETIN 分子名称: RETINOIC ACID, RETINOL BINDING PROTEIN, TRANSTHYRETIN 著者 Monaco, H.L, Rizzi, M, Coda, A. 登録日 1995-02-20 公開日 1996-04-11 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein. Science, 268, 1995
2RD7	Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins 分子名称: CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain 著者 Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. 登録日 2007-09-21 公開日 2008-05-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J. Biol. Chem., 286, 2011
3BSZ	Crystal structure of the transthyretin-retinol binding protein-Fab complex 分子名称: Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ... 著者 Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R. 登録日 2007-12-27 公開日 2008-11-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein. Febs J., 275, 2008
4MVL	Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40 分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4MVI	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40) 分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin 著者 Eichinger, A, Skerra, A. 登録日 2013-09-24 公開日 2015-08-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4QAF	Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109) 分子名称: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ... 著者 Giese, T, Skerra, A. 登録日 2014-05-04 公開日 2015-05-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold To be Published
7NYD	cryoEM structure of 2C9-sMAC 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Menny, A, Couves, E.C, Bubeck, D. 登録日 2021-03-22 公開日 2021-10-06 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structural basis of soluble membrane attack complex packaging for clearance. Nat Commun, 12, 2021
6H03	OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... 著者 Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. 登録日 2018-07-06 公開日 2018-12-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018
6H04	Closed conformation of the Membrane Attack Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... 著者 Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. 登録日 2018-07-06 公開日 2018-12-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Nat Commun, 9, 2018

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