PDB: 94 件ウェブページステータス検索Chemie searchBIRD

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5W0W	Crystal structure of Protein Phosphatase 2A bound to TIPRL 分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... 著者 Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. 登録日 2017-06-01 公開日 2018-01-17 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Methylation-regulated decommissioning of multimeric PP2A complexes. Nat Commun, 8, 2017
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
3C5W	Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme 分子名称: PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 著者 Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. 登録日 2008-02-01 公開日 2008-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
8SO0	Cryo-EM structure of the PP2A:B55-FAM122A complex 分子名称: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, ... 著者 Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. 登録日 2023-04-28 公開日 2023-10-25 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.79961 Å) 主引用文献 Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
2NPP	Structure of the Protein Phosphatase 2A Holoenzyme 分子名称: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... 著者 Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y. 登録日 2006-10-28 公開日 2006-12-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the protein phosphatase 2A holoenzyme Cell(Cambridge,Mass.), 127, 2006
8TWI	Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body 分子名称: FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. 登録日 2023-08-21 公開日 2023-11-01 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8TWE	Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body 分子名称: PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. 登録日 2023-08-21 公開日 2023-11-01 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.55 Å) 主引用文献 Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8TTB	Cryo-EM structure of the PP2A:B55-ARPP19 complex 分子名称: FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. 登録日 2023-08-13 公開日 2023-10-25 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
8U89	The structure of the PP2A-B56Delta holoenzyme mutant - E197K 分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Wu, C.G, Xing, Y. 登録日 2023-09-16 公開日 2024-01-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc.Natl.Acad.Sci.USA, 121, 2024
8U1X	The structure of the PP2A-B56Delta holoenzyme mutant - E197K 分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Wu, C.G, Xing, Y. 登録日 2023-09-04 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc.Natl.Acad.Sci.USA, 121, 2024
2PF4	Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit 分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION 著者 Cho, U, Morrone, S, Xu, W. 登録日 2007-04-03 公開日 2007-08-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis of PP2A inhibition by small t antigen. Plos Biol., 5, 2007
2NYL	Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated 分子名称: MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ... 著者 Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y. 登録日 2006-11-20 公開日 2006-12-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS 分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 著者 Gonzalez, A, Fung, H.Y.J, Chook, Y.M. 登録日 2023-04-12 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
8RBX	Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. 登録日 2023-12-05 公開日 2024-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
8RC4	Structure of Integrator-PP2A complex 分子名称: DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... 著者 Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. 登録日 2023-12-06 公開日 2024-02-07 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
8RBZ	Structure of Integrator-PP2A-SOSS-CTD post-termination complex 分子名称: DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... 著者 Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. 登録日 2023-12-05 公開日 2024-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
2NYM	Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit 分子名称: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... 著者 Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y. 登録日 2006-11-21 公開日 2006-12-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
2PKG	Structure of a complex between the A subunit of protein phosphatase 2A and the small t antigen of SV40 分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION 著者 Jeffrey, P.D, Shi, Y. 登録日 2007-04-17 公開日 2007-05-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nat.Struct.Mol.Biol., 14, 2007

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