2PKG

Structure of a complex between the A subunit of protein phosphatase 2A and the small t antigen of SV40

Summary for 2PKG

Entry DOI	10.2210/pdb2pkg/pdb
Descriptor	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION (3 entities in total)
Functional Keywords	protein phosphatase 2a, small t antigen, sv40, regulation, hydrolase regulator-viral protein complex, hydrolase regulator/viral protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (By similarity): P30153 Host cytoplasm: P03081
Total number of polymer chains	4
Total formula weight	150279.67
Authors	Jeffrey, P.D.,Shi, Y. (deposition date: 2007-04-17, release date: 2007-05-15, Last modification date: 2024-02-21)
Primary citation	Chen, Y.,Xu, Y.,Bao, Q.,Xing, Y.,Li, Z.,Lin, Z.,Stock, J.B.,Jeffrey, P.D.,Shi, Y. Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nat.Struct.Mol.Biol., 14:527-534, 2007 Cited by PubMed: 17529992 DOI: 10.1038/nsmb1254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation