PDB: 684 件ウェブページステータス検索Chemie searchBIRD

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7U8L	Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83 分子名称: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ... 著者 Zhu, X, Wilson, I.A. 登録日 2022-03-08 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.56 Å) 主引用文献 Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7U8J	Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83 分子名称: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ... 著者 Zhu, X, Wilson, I.A. 登録日 2022-03-08 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.9 Å) 主引用文献 Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7TZ5	Cryo-EM structure of antibody TJ5-5 bound to H3 COBRA TJ5 hemagglutinin 分子名称: Hemagglutinin, TJ5-5 heavy chain, TJ5-5 light chain 著者 Abbadi, N.S, Mousa, J.J. 登録日 2022-02-15 公開日 2022-07-06 最終更新日 2022-09-21 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Differential Recognition of Computationally Optimized H3 Hemagglutinin Influenza Vaccine Candidates by Human Antibodies. J.Virol., 96, 2022
7TRI	Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2) 分子名称: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ... 著者 McCarthy, K.R. 登録日 2022-01-28 公開日 2023-08-02 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7TRH	Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181) 分子名称: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain 著者 McCarthy, K.R. 登録日 2022-01-28 公開日 2023-08-02 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7T3D	CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ... 著者 Han, J, Ward, A.B. 登録日 2021-12-07 公開日 2022-01-12 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature, 602, 2022
7T1V	Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... 著者 Zhu, X, Wilson, I.A. 登録日 2021-12-02 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses. J.Virol., 96, 2022
7SCO	Structure of H1 influenza hemagglutinin bound to Fab 310-39G10 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ... 著者 Torrents de la Pena, A, Ward, A.B. 登録日 2021-09-28 公開日 2022-08-24 最終更新日 2022-09-28 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7SCN	Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-63E6 Fab, Heavy Chain, ... 著者 Ward, A, Torrents de la Pena, A. 登録日 2021-09-28 公開日 2022-08-24 最終更新日 2022-09-28 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7RDH	Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ... 著者 Kadam, R.U, Wilson, I.A. 登録日 2021-07-09 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 分子名称: 1,2-ETHANEDIOL, Hemagglutinin 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-07-08 公開日 2021-08-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
7QA4	Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Milder, F.J, Langedijk, J.P.M. 登録日 2021-11-16 公開日 2022-02-02 最終更新日 2022-03-30 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. Proc.Natl.Acad.Sci.USA, 119, 2022
7MFG	Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ... 著者 Gorman, J, Kwong, P.D. 登録日 2021-04-09 公開日 2021-11-03 最終更新日 2022-03-09 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7MEM	CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ... 著者 Han, J, Ward, A. 登録日 2021-04-06 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13, 2021
7L0L	Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ... 著者 Gorman, J, Kwong, P.D. 登録日 2020-12-11 公開日 2021-11-03 最終更新日 2022-03-09 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7KQI	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses 分子名称: 1209 Fab heavy chain, 1209 Fab light chain, Hemagglutinin, ... 著者 Bajic, G, Harrison, S.C. 登録日 2020-11-16 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KQH	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses 分子名称: 2365 Fab heavy chain, 2365 Fab light chain, Hemagglutinin, ... 著者 Bajic, G, Harrison, S.C. 登録日 2020-11-16 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KQG	Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses 分子名称: 1272 Fab heavy chain, 1272 Fab light chain, Hemagglutinin, ... 著者 Bajic, G, Harrison, S.C. 登録日 2020-11-16 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses. Acs Infect Dis., 7, 2021
7KNA	Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5 著者 Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-11-04 公開日 2021-03-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature, 592, 2021
7KC1	Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... 著者 Gorman, J, Kwong, P.D. 登録日 2020-10-04 公開日 2021-05-12 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses. Front Immunol, 12, 2021
7K3B	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Gui, M, Gao, J, Xiang, Y. 登録日 2020-09-10 公開日 2020-11-11 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K3A	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Gui, M, Gao, J, Xiang, Y. 登録日 2020-09-10 公開日 2020-11-11 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K39	Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation A, neutral pH-like 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Gui, M, Gao, J, Xiang, Y. 登録日 2020-09-10 公開日 2020-11-11 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7K37	Structure of full-length influenza HA with a head-binding antibody at pH 7.8 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Gui, M, Xiang, Y, Gao, J. 登録日 2020-09-10 公開日 2020-11-11 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural intermediates in the low pH-induced transition of influenza hemagglutinin. Plos Pathog., 16, 2020
7JPD	Crystal structure of the trimeric full length mature hemagglutinin from influenza A virus A/Fort Monmouth/1/1947 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-08-07 公開日 2021-10-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site. Sci Rep, 13, 2023

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