PDB: 90 件ウェブページステータス検索Chemie searchBIRD

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5FWP	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-10-26 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWL	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-07-06 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
7ZUB	Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex 分子名称: (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... 著者 Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. 登録日 2022-05-12 公開日 2022-11-23 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
7ZR0	CryoEM structure of HSP90-CDC37-BRAF(V600E) complex. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-14 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR5	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-14 最終更新日 2022-12-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-28 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
8U1L	Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, Hsp90 co-chaperone Cdc37, ... 著者 Finci, L.I, Simanshu, D.K. 登録日 2023-09-01 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7, 2024
8QMO	Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... 著者 Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. 登録日 2023-09-24 公開日 2024-01-10 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8GAE	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-02-22 公開日 2023-04-26 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-03-08 公開日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8H77	Hsp90-AhR-p23-XAP2 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... 著者 Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. 登録日 2022-10-19 公開日 2023-01-04 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... 著者 Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. 登録日 2020-11-30 公開日 2021-12-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
7KRJ	The GR-Maturation Complex: Glucocorticoid Receptor in complex with Hsp90 and co-chaperone p23 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Wang, Y.-R, Agard, D.A. 登録日 2020-11-20 公開日 2022-01-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.56 Å) 主引用文献 Structure of Hsp90-p23-GR reveals the Hsp90 client-remodelling mechanism. Nature, 601, 2021

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