PDB: 93 件ウェブページステータス検索Chemie searchBIRD

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5FWK	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-17 公開日 2016-07-06 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWP	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-10-26 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWL	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-07-06 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
5FWM	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-07-06 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-03-08 公開日 2023-05-03 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8H77	Hsp90-AhR-p23-XAP2 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... 著者 Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. 登録日 2022-10-19 公開日 2023-01-04 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
8GAE	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-02-22 公開日 2023-04-26 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
7Y04	Hsp90-AhR-p23 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... 著者 Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. 登録日 2022-06-03 公開日 2023-01-04 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
7Z38	Structure of the RAF1-HSP90-CDC37 complex (RHC-I) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. 登録日 2022-03-01 公開日 2022-09-14 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
7Z37	Structure of the RAF1-HSP90-CDC37 complex (RHC-II) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. 登録日 2022-03-01 公開日 2022-09-14 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
7ZUB	Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex 分子名称: (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... 著者 Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. 登録日 2022-05-12 公開日 2022-11-23 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
7ZR0	CryoEM structure of HSP90-CDC37-BRAF(V600E) complex. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-14 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR5	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-14 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-28 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... 著者 Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. 登録日 2020-11-30 公開日 2021-12-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
7KRJ	The GR-Maturation Complex: Glucocorticoid Receptor in complex with Hsp90 and co-chaperone p23 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Wang, Y.-R, Agard, D.A. 登録日 2020-11-20 公開日 2022-01-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.56 Å) 主引用文献 Structure of Hsp90-p23-GR reveals the Hsp90 client-remodelling mechanism. Nature, 601, 2021

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