7KW7
Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR
Summary for 7KW7
Entry DOI | 10.2210/pdb7kw7/pdb |
EMDB information | 23050 |
Descriptor | Heat shock protein HSP 90-alpha, Heat shock 70 kDa protein 1A, Stress-induced-phosphoprotein 1, ... (7 entities in total) |
Functional Keywords | client-loading, chaperone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 459237.13 |
Authors | Wang, R.Y.,Noddings, C.M.,Kirschke, E.,Myasnikov, A.,Johnson, J.L.,Agard, D.A. (deposition date: 2020-11-30, release date: 2021-12-08, Last modification date: 2024-05-29) |
Primary citation | Wang, R.Y.,Noddings, C.M.,Kirschke, E.,Myasnikov, A.G.,Johnson, J.L.,Agard, D.A. Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601:460-464, 2022 Cited by PubMed: 34937942DOI: 10.1038/s41586-021-04252-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.57 Å) |
Structure validation
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