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7KW7

Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR

Functional Information from GO Data
ChainGOidnamespacecontents
A0001764biological_processneuron migration
A0001934biological_processpositive regulation of protein phosphorylation
A0002134molecular_functionUTP binding
A0002135molecular_functionCTP binding
A0002218biological_processactivation of innate immune response
A0002230biological_processpositive regulation of defense response to virus by host
A0003009biological_processskeletal muscle contraction
A0003723molecular_functionRNA binding
A0003729molecular_functionmRNA binding
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005525molecular_functionGTP binding
A0005576cellular_componentextracellular region
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006457biological_processprotein folding
A0006839biological_processmitochondrial transport
A0006986biological_processresponse to unfolded protein
A0007004biological_processtelomere maintenance via telomerase
A0009408biological_processresponse to heat
A0009409biological_processresponse to cold
A0009410biological_processresponse to xenobiotic stimulus
A0009651biological_processresponse to salt stress
A0009986cellular_componentcell surface
A0010592biological_processpositive regulation of lamellipodium assembly
A0010659biological_processcardiac muscle cell apoptotic process
A0016020cellular_componentmembrane
A0016323cellular_componentbasolateral plasma membrane
A0016324cellular_componentapical plasma membrane
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0017098molecular_functionsulfonylurea receptor binding
A0019903molecular_functionprotein phosphatase binding
A0023026molecular_functionMHC class II protein complex binding
A0030235molecular_functionnitric-oxide synthase regulator activity
A0030911molecular_functionTPR domain binding
A0031396biological_processregulation of protein ubiquitination
A0031526cellular_componentbrush border membrane
A0031625molecular_functionubiquitin protein ligase binding
A0032273biological_processpositive regulation of protein polymerization
A0032564molecular_functiondATP binding
A0032728biological_processpositive regulation of interferon-beta production
A0032880biological_processregulation of protein localization
A0032991cellular_componentprotein-containing complex
A0034605biological_processcellular response to heat
A0034774cellular_componentsecretory granule lumen
A0036126cellular_componentsperm flagellum
A0042026biological_processprotein refolding
A0042220biological_processresponse to cocaine
A0042307biological_processpositive regulation of protein import into nucleus
A0042470cellular_componentmelanosome
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0042826molecular_functionhistone deacetylase binding
A0042981biological_processregulation of apoptotic process
A0043025cellular_componentneuronal cell body
A0043202cellular_componentlysosomal lumen
A0043209cellular_componentmyelin sheath
A0043254biological_processregulation of protein-containing complex assembly
A0043335biological_processprotein unfolding
A0043627biological_processresponse to estrogen
A0044183molecular_functionprotein folding chaperone
A0044294cellular_componentdendritic growth cone
A0044295cellular_componentaxonal growth cone
A0044325molecular_functiontransmembrane transporter binding
A0045040biological_processprotein insertion into mitochondrial outer membrane
A0045429biological_processpositive regulation of nitric oxide biosynthetic process
A0045732biological_processpositive regulation of protein catabolic process
A0045793biological_processpositive regulation of cell size
A0046677biological_processresponse to antibiotic
A0048156molecular_functiontau protein binding
A0048471cellular_componentperinuclear region of cytoplasm
A0050821biological_processprotein stabilization
A0051020molecular_functionGTPase binding
A0051022molecular_functionRho GDP-dissociation inhibitor binding
A0051082molecular_functionunfolded protein binding
A0051131biological_processchaperone-mediated protein complex assembly
A0060255biological_processregulation of macromolecule metabolic process
A0060452biological_processpositive regulation of cardiac muscle contraction
A0061684biological_processchaperone-mediated autophagy
A0062023cellular_componentcollagen-containing extracellular matrix
A0070062cellular_componentextracellular exosome
A0070182molecular_functionDNA polymerase binding
A0071682cellular_componentendocytic vesicle lumen
A0097110molecular_functionscaffold protein binding
A0097226cellular_componentsperm mitochondrial sheath
A0097524cellular_componentsperm plasma membrane
A0097718molecular_functiondisordered domain specific binding
A0098586biological_processcellular response to virus
A0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
A0140662molecular_functionATP-dependent protein folding chaperone
A1902949biological_processpositive regulation of tau-protein kinase activity
A1904813cellular_componentficolin-1-rich granule lumen
A1905323biological_processtelomerase holoenzyme complex assembly
A1990782molecular_functionprotein tyrosine kinase binding
B0001764biological_processneuron migration
B0001934biological_processpositive regulation of protein phosphorylation
B0002134molecular_functionUTP binding
B0002135molecular_functionCTP binding
B0002218biological_processactivation of innate immune response
B0002230biological_processpositive regulation of defense response to virus by host
B0003009biological_processskeletal muscle contraction
B0003723molecular_functionRNA binding
B0003729molecular_functionmRNA binding
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005525molecular_functionGTP binding
B0005576cellular_componentextracellular region
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006457biological_processprotein folding
B0006839biological_processmitochondrial transport
B0006986biological_processresponse to unfolded protein
B0007004biological_processtelomere maintenance via telomerase
B0009408biological_processresponse to heat
B0009409biological_processresponse to cold
B0009410biological_processresponse to xenobiotic stimulus
B0009651biological_processresponse to salt stress
B0009986cellular_componentcell surface
B0010592biological_processpositive regulation of lamellipodium assembly
B0010659biological_processcardiac muscle cell apoptotic process
B0016020cellular_componentmembrane
B0016323cellular_componentbasolateral plasma membrane
B0016324cellular_componentapical plasma membrane
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0017098molecular_functionsulfonylurea receptor binding
B0019903molecular_functionprotein phosphatase binding
B0023026molecular_functionMHC class II protein complex binding
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030911molecular_functionTPR domain binding
B0031396biological_processregulation of protein ubiquitination
B0031526cellular_componentbrush border membrane
B0031625molecular_functionubiquitin protein ligase binding
B0032273biological_processpositive regulation of protein polymerization
B0032564molecular_functiondATP binding
B0032728biological_processpositive regulation of interferon-beta production
B0032880biological_processregulation of protein localization
B0032991cellular_componentprotein-containing complex
B0034605biological_processcellular response to heat
B0034774cellular_componentsecretory granule lumen
B0036126cellular_componentsperm flagellum
B0042026biological_processprotein refolding
B0042220biological_processresponse to cocaine
B0042307biological_processpositive regulation of protein import into nucleus
B0042470cellular_componentmelanosome
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042826molecular_functionhistone deacetylase binding
B0042981biological_processregulation of apoptotic process
B0043025cellular_componentneuronal cell body
B0043202cellular_componentlysosomal lumen
B0043209cellular_componentmyelin sheath
B0043254biological_processregulation of protein-containing complex assembly
B0043335biological_processprotein unfolding
B0043627biological_processresponse to estrogen
B0044183molecular_functionprotein folding chaperone
B0044294cellular_componentdendritic growth cone
B0044295cellular_componentaxonal growth cone
B0044325molecular_functiontransmembrane transporter binding
B0045040biological_processprotein insertion into mitochondrial outer membrane
B0045429biological_processpositive regulation of nitric oxide biosynthetic process
B0045732biological_processpositive regulation of protein catabolic process
B0045793biological_processpositive regulation of cell size
B0046677biological_processresponse to antibiotic
B0048156molecular_functiontau protein binding
B0048471cellular_componentperinuclear region of cytoplasm
B0050821biological_processprotein stabilization
B0051020molecular_functionGTPase binding
B0051022molecular_functionRho GDP-dissociation inhibitor binding
B0051082molecular_functionunfolded protein binding
B0051131biological_processchaperone-mediated protein complex assembly
B0060255biological_processregulation of macromolecule metabolic process
B0060452biological_processpositive regulation of cardiac muscle contraction
B0061684biological_processchaperone-mediated autophagy
B0062023cellular_componentcollagen-containing extracellular matrix
B0070062cellular_componentextracellular exosome
B0070182molecular_functionDNA polymerase binding
B0071682cellular_componentendocytic vesicle lumen
B0097110molecular_functionscaffold protein binding
B0097226cellular_componentsperm mitochondrial sheath
B0097524cellular_componentsperm plasma membrane
B0097718molecular_functiondisordered domain specific binding
B0098586biological_processcellular response to virus
B0099072biological_processregulation of postsynaptic membrane neurotransmitter receptor levels
B0140662molecular_functionATP-dependent protein folding chaperone
B1902949biological_processpositive regulation of tau-protein kinase activity
B1904813cellular_componentficolin-1-rich granule lumen
B1905323biological_processtelomerase holoenzyme complex assembly
B1990782molecular_functionprotein tyrosine kinase binding
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0001618molecular_functionvirus receptor activity
C0001664molecular_functionG protein-coupled receptor binding
C0003714molecular_functiontranscription corepressor activity
C0003723molecular_functionRNA binding
C0005102molecular_functionsignaling receptor binding
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005783cellular_componentendoplasmic reticulum
C0005813cellular_componentcentrosome
C0005814cellular_componentcentriole
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005925cellular_componentfocal adhesion
C0006402biological_processmRNA catabolic process
C0006986biological_processresponse to unfolded protein
C0007041biological_processlysosomal transport
C0007165biological_processsignal transduction
C0008180cellular_componentCOP9 signalosome
C0008285biological_processnegative regulation of cell population proliferation
C0010628biological_processpositive regulation of gene expression
C0016234cellular_componentinclusion body
C0016235cellular_componentaggresome
C0016607cellular_componentnuclear speck
C0016887molecular_functionATP hydrolysis activity
C0019899molecular_functionenzyme binding
C0030308biological_processnegative regulation of cell growth
C0030512biological_processnegative regulation of transforming growth factor beta receptor signaling pathway
C0031072molecular_functionheat shock protein binding
C0031249molecular_functiondenatured protein binding
C0031396biological_processregulation of protein ubiquitination
C0031397biological_processnegative regulation of protein ubiquitination
C0031625molecular_functionubiquitin protein ligase binding
C0031982cellular_componentvesicle
C0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
C0032757biological_processpositive regulation of interleukin-8 production
C0032991cellular_componentprotein-containing complex
C0033120biological_processpositive regulation of RNA splicing
C0034599biological_processcellular response to oxidative stress
C0034605biological_processcellular response to heat
C0034620biological_processcellular response to unfolded protein
C0038177molecular_functiondeath receptor agonist activity
C0042026biological_processprotein refolding
C0042826molecular_functionhistone deacetylase binding
C0043066biological_processnegative regulation of apoptotic process
C0044183molecular_functionprotein folding chaperone
C0045296molecular_functioncadherin binding
C0045648biological_processpositive regulation of erythrocyte differentiation
C0046034biological_processATP metabolic process
C0046718biological_processsymbiont entry into host cell
C0048018molecular_functionreceptor ligand activity
C0048471cellular_componentperinuclear region of cytoplasm
C0050821biological_processprotein stabilization
C0051082molecular_functionunfolded protein binding
C0051085biological_processchaperone cofactor-dependent protein refolding
C0051092biological_processpositive regulation of NF-kappaB transcription factor activity
C0051131biological_processchaperone-mediated protein complex assembly
C0051787molecular_functionmisfolded protein binding
C0055131molecular_functionC3HC4-type RING finger domain binding
C0070062cellular_componentextracellular exosome
C0070370biological_processcellular heat acclimation
C0070434biological_processpositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
C0071383biological_processcellular response to steroid hormone stimulus
C0072562cellular_componentblood microparticle
C0090063biological_processpositive regulation of microtubule nucleation
C0090084biological_processnegative regulation of inclusion body assembly
C0097718molecular_functiondisordered domain specific binding
C0140416molecular_functiontranscription regulator inhibitor activity
C0140545molecular_functionATP-dependent protein disaggregase activity
C0140662molecular_functionATP-dependent protein folding chaperone
C1901029biological_processnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
C1901673biological_processregulation of mitotic spindle assembly
C1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
C1902380biological_processpositive regulation of endoribonuclease activity
C1903265biological_processpositive regulation of tumor necrosis factor-mediated signaling pathway
C1904813cellular_componentficolin-1-rich granule lumen
C1990904cellular_componentribonucleoprotein complex
C2001240biological_processnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0001618molecular_functionvirus receptor activity
D0001664molecular_functionG protein-coupled receptor binding
D0003714molecular_functiontranscription corepressor activity
D0003723molecular_functionRNA binding
D0005102molecular_functionsignaling receptor binding
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005783cellular_componentendoplasmic reticulum
D0005813cellular_componentcentrosome
D0005814cellular_componentcentriole
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005925cellular_componentfocal adhesion
D0006402biological_processmRNA catabolic process
D0006986biological_processresponse to unfolded protein
D0007041biological_processlysosomal transport
D0007165biological_processsignal transduction
D0008180cellular_componentCOP9 signalosome
D0008285biological_processnegative regulation of cell population proliferation
D0010628biological_processpositive regulation of gene expression
D0016234cellular_componentinclusion body
D0016235cellular_componentaggresome
D0016607cellular_componentnuclear speck
D0016887molecular_functionATP hydrolysis activity
D0019899molecular_functionenzyme binding
D0030308biological_processnegative regulation of cell growth
D0030512biological_processnegative regulation of transforming growth factor beta receptor signaling pathway
D0031072molecular_functionheat shock protein binding
D0031249molecular_functiondenatured protein binding
D0031396biological_processregulation of protein ubiquitination
D0031397biological_processnegative regulation of protein ubiquitination
D0031625molecular_functionubiquitin protein ligase binding
D0031982cellular_componentvesicle
D0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
D0032757biological_processpositive regulation of interleukin-8 production
D0032991cellular_componentprotein-containing complex
D0033120biological_processpositive regulation of RNA splicing
D0034599biological_processcellular response to oxidative stress
D0034605biological_processcellular response to heat
D0034620biological_processcellular response to unfolded protein
D0038177molecular_functiondeath receptor agonist activity
D0042026biological_processprotein refolding
D0042826molecular_functionhistone deacetylase binding
D0043066biological_processnegative regulation of apoptotic process
D0044183molecular_functionprotein folding chaperone
D0045296molecular_functioncadherin binding
D0045648biological_processpositive regulation of erythrocyte differentiation
D0046034biological_processATP metabolic process
D0046718biological_processsymbiont entry into host cell
D0048018molecular_functionreceptor ligand activity
D0048471cellular_componentperinuclear region of cytoplasm
D0050821biological_processprotein stabilization
D0051082molecular_functionunfolded protein binding
D0051085biological_processchaperone cofactor-dependent protein refolding
D0051092biological_processpositive regulation of NF-kappaB transcription factor activity
D0051131biological_processchaperone-mediated protein complex assembly
D0051787molecular_functionmisfolded protein binding
D0055131molecular_functionC3HC4-type RING finger domain binding
D0070062cellular_componentextracellular exosome
D0070370biological_processcellular heat acclimation
D0070434biological_processpositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
D0071383biological_processcellular response to steroid hormone stimulus
D0072562cellular_componentblood microparticle
D0090063biological_processpositive regulation of microtubule nucleation
D0090084biological_processnegative regulation of inclusion body assembly
D0097718molecular_functiondisordered domain specific binding
D0140416molecular_functiontranscription regulator inhibitor activity
D0140545molecular_functionATP-dependent protein disaggregase activity
D0140662molecular_functionATP-dependent protein folding chaperone
D1901029biological_processnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
D1901673biological_processregulation of mitotic spindle assembly
D1902236biological_processnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
D1902380biological_processpositive regulation of endoribonuclease activity
D1903265biological_processpositive regulation of tumor necrosis factor-mediated signaling pathway
D1904813cellular_componentficolin-1-rich granule lumen
D1990904cellular_componentribonucleoprotein complex
D2001240biological_processnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
E0003723molecular_functionRNA binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005794cellular_componentGolgi apparatus
E0005829cellular_componentcytosol
E0032991cellular_componentprotein-containing complex
E0051879molecular_functionHsp90 protein binding
E0098761biological_processcellular response to interleukin-7
E0101031cellular_componentprotein folding chaperone complex
E0120293cellular_componentdynein axonemal particle
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0000785cellular_componentchromatin
F0000977molecular_functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
F0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
F0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
F0001046molecular_functioncore promoter sequence-specific DNA binding
F0001227molecular_functionDNA-binding transcription repressor activity, RNA polymerase II-specific
F0001228molecular_functionDNA-binding transcription activator activity, RNA polymerase II-specific
F0003677molecular_functionDNA binding
F0003700molecular_functionDNA-binding transcription factor activity
F0003723molecular_functionRNA binding
F0004879molecular_functionnuclear receptor activity
F0004883molecular_functionnuclear glucocorticoid receptor activity
F0005496molecular_functionsteroid binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005759cellular_componentmitochondrial matrix
F0005813cellular_componentcentrosome
F0005819cellular_componentspindle
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0006111biological_processregulation of gluconeogenesis
F0006325biological_processchromatin organization
F0006355biological_processregulation of DNA-templated transcription
F0006357biological_processregulation of transcription by RNA polymerase II
F0006915biological_processapoptotic process
F0007059biological_processchromosome segregation
F0007165biological_processsignal transduction
F0008211biological_processglucocorticoid metabolic process
F0008270molecular_functionzinc ion binding
F0010467biological_processgene expression
F0014004biological_processmicroglia differentiation
F0016020cellular_componentmembrane
F0016607cellular_componentnuclear speck
F0017025molecular_functionTBP-class protein binding
F0019901molecular_functionprotein kinase binding
F0030325biological_processadrenal gland development
F0030518biological_processnuclear receptor-mediated steroid hormone signaling pathway
F0031946biological_processregulation of glucocorticoid biosynthetic process
F0032991cellular_componentprotein-containing complex
F0034056molecular_functionestrogen response element binding
F0035249biological_processsynaptic transmission, glutamatergic
F0042711biological_processmaternal behavior
F0042802molecular_functionidentical protein binding
F0042921biological_processnuclear receptor-mediated glucocorticoid signaling pathway
F0043402biological_processglucocorticoid mediated signaling pathway
F0043525biological_processpositive regulation of neuron apoptotic process
F0043565molecular_functionsequence-specific DNA binding
F0045202cellular_componentsynapse
F0045892biological_processnegative regulation of DNA-templated transcription
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0046872molecular_functionmetal ion binding
F0048708biological_processastrocyte differentiation
F0051301biological_processcell division
F0051879molecular_functionHsp90 protein binding
F0060603biological_processmammary gland duct morphogenesis
F0061744biological_processmotor behavior
F0071383biological_processcellular response to steroid hormone stimulus
F0071385biological_processcellular response to glucocorticoid stimulus
F0071549biological_processcellular response to dexamethasone stimulus
F0071560biological_processcellular response to transforming growth factor beta stimulus
F0150076biological_processneuroinflammatory response
F1902895biological_processpositive regulation of miRNA transcription
F1990239molecular_functionsteroid hormone binding
F1990837molecular_functionsequence-specific double-stranded DNA binding
Functional Information from PROSITE/UniProt
site_idPS00031
Number of Residues27
DetailsNUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. ClvCs.Deasgc.HYgvltCgsCkvFFkR
ChainResidueDetails
FCYS421-ARG447

site_idPS00297
Number of Residues8
DetailsHSP70_1 Heat shock hsp70 proteins family signature 1. IDLGTTyS
ChainResidueDetails
CILE9-SER16

site_idPS00298
Number of Residues10
DetailsHSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE
ChainResidueDetails
ATYR38-GLU47

site_idPS00329
Number of Residues14
DetailsHSP70_2 Heat shock hsp70 proteins family signature 2. IFDLGGGTfdvSIL
ChainResidueDetails
CILE197-LEU210

site_idPS01036
Number of Residues15
DetailsHSP70_3 Heat shock hsp70 proteins family signature 3. LvLvGGsTRIPkVqK
ChainResidueDetails
CLEU334-LYS348

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues75
DetailsDNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
FPRO418-THR493
DGLY339
CLYS71
CGLY202
CGLU268
CGLY339
DGLY12
DLYS71
DGLY202
DGLU268

site_idSWS_FT_FI2
Number of Residues39
DetailsZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407
ChainResidueDetails
FCYS421-CYS441
FCYS457-CYS476
ELYS312
ELYS325
ELYS344
ELYS446

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163
ChainResidueDetails
FTHR8
DLYS77
BTHR5
BTHR7

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P06537
ChainResidueDetails
FARG23
CLYS246
CLYS348
DLYS108
DLYS246
DLYS348

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
FSER45
DARG469

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P06537
ChainResidueDetails
FSER113
FSER141

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
FSER134
CSER633
DSER631
DSER633

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:12000743, ECO:0000269|PubMed:18483179, ECO:0000269|PubMed:25847991, ECO:0007744|PubMed:24275569
ChainResidueDetails
FSER203
DTHR636
BTYR313
BTYR492

site_idSWS_FT_FI9
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:12000743, ECO:0000269|PubMed:18483179, ECO:0000269|PubMed:25847991
ChainResidueDetails
FSER211
ELYS210
ALYS489
ALYS585
BLYS443
BLYS458
BLYS489
BLYS585

site_idSWS_FT_FI10
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:18483179, ECO:0007744|PubMed:18669648
ChainResidueDetails
FSER226
BSER453

site_idSWS_FT_FI11
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163
ChainResidueDetails
FSER267
ASER641
BSER476
BSER641

site_idSWS_FT_FI12
Number of Residues1
DetailsMOD_RES: Phosphoserine; by GSK3-beta => ECO:0000269|PubMed:18838540
ChainResidueDetails
FSER404
BCYS598

site_idSWS_FT_FI13
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:19141540
ChainResidueDetails
FLYS480
FLYS492
FLYS494
FLYS495

site_idSWS_FT_FI14
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
FLYS258

site_idSWS_FT_FI15
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:12144530
ChainResidueDetails
FLYS703

site_idSWS_FT_FI16
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
ChainResidueDetails
FLYS277

site_idSWS_FT_FI17
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211
ChainResidueDetails
FLYS293

site_idSWS_FT_FI18
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P06537
ChainResidueDetails
FLYS419

221371

PDB entries from 2024-06-19

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