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6USR
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BU of 6usr by Molmil
Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp
分子名称: DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ...
著者Schaich, M.A, Freudenthal, B.D.
登録日2019-10-28
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Mechanisms of nucleotide selection by telomerase.
Elife, 9, 2020
7TRD
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BU of 7trd by Molmil
Human telomerase catalytic core structure at 3.3 Angstrom
分子名称: Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7TRF
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BU of 7trf by Molmil
Human telomerase catalytic core RNP with H2A/H2B
分子名称: Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7TRE
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BU of 7tre by Molmil
Human telomerase catalytic core with shelterin protein TPP1
分子名称: Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7UIM
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BU of 7uim by Molmil
CryoEM Structure of an Group II Intron Retroelement (apo-complex)
分子名称: AMMONIUM ION, E.r IIC Intron, Group II intron reverse transcriptase/maturase, ...
著者Chung, K, Xu, L.
登録日2022-03-29
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of a mobile intron retroelement poised to attack its structured DNA target
Science, 378, 2022
7UIN
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BU of 7uin by Molmil
CryoEM Structure of an Group II Intron Retroelement
分子名称: AMMONIUM ION, DNA (37-MER), E.r IIC Intron, ...
著者Chung, K, Xu, L.
登録日2022-03-29
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of a mobile intron retroelement poised to attack its structured DNA target
Science, 378, 2022
7V99
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BU of 7v99 by Molmil
catalytic core of human telomerase holoenzyme
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ...
著者Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
登録日2021-08-24
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
4OL8
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BU of 4ol8 by Molmil
Ty3 reverse transcriptase bound to DNA/RNA
分子名称: 5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3', 5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3', Reverse transcriptase/ribonuclease H, ...
著者Nowak, E, Miller, J.T, Bona, M.K, Studnicka, J, Szczepanowski, R.H, Jurkowski, J, Le Grice, S.F.J, Nowotny, M.
登録日2014-01-23
公開日2014-03-05
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Nat.Struct.Mol.Biol., 21, 2014
7O0H
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BU of 7o0h by Molmil
Structure of the foamy viral protease-reverse transcriptase dRH in complex with ds DNA.
分子名称: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol
著者Nowak, E, Nowacka, M, Nowotny, M.
登録日2021-03-26
公開日2021-06-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
7Q5B
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BU of 7q5b by Molmil
Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene
分子名称: DNA (19-MER), DNA (31-MER), DNA (34-MER), ...
著者Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A.
登録日2021-11-03
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Nat Commun, 12, 2021
4KSE
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BU of 4kse by Molmil
Crystal structure of a HIV p51 (219-230) deletion mutant
分子名称: 1,2-ETHANEDIOL, HIV p51 subunit
著者Zheng, X, Mueller, G.A, Derose, E.F, Pedersen, L.C, Gabel, S.A, Cuneo, M.J, Krahn, J.M, London, R.E.
登録日2013-05-17
公開日2014-08-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.677 Å)
主引用文献Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation.
Nucleic Acids Res., 42, 2014
7QXA
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BU of 7qxa by Molmil
Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXB
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BU of 7qxb by Molmil
Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXS
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BU of 7qxs by Molmil
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-27
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
3DU5
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BU of 3du5 by Molmil
Structure of the catalytic subunit of telomerase, TERT
分子名称: Telomerase reverse transcriptase
著者Skordalakes, E.
登録日2008-07-16
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature, 455, 2008
3DU6
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BU of 3du6 by Molmil
Structure of the catalytic subunit of telomerase, TERT
分子名称: Telomerase reverse transcriptase
著者Skordalakes, E.
登録日2008-07-16
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature, 455, 2008
7KFU
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BU of 7kfu by Molmil
Cas6-RT-Cas1--Cas2 complex
分子名称: Cas2, Cas6-RT-Cas1
著者Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G.
登録日2020-10-14
公開日2021-03-31
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
7KFT
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BU of 7kft by Molmil
Partial Cas6-RT-Cas1--Cas2 complex
分子名称: Cas2, Cas6-RT-Cas1
著者Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G.
登録日2020-10-14
公開日2021-03-31
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
7K9Y
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BU of 7k9y by Molmil
GsI-IIC RT Template-Switching Complex (twinned)
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
著者Stamos, J.L, Lentzsch, A.M.
登録日2020-09-29
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase.
J.Biol.Chem., 297, 2021
7KQN
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BU of 7kqn by Molmil
Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Choi, W.S, Weng, P.J, Yang, W.
登録日2020-11-17
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KQM
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BU of 7kqm by Molmil
Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ...
著者Choi, W.S, Weng, P.J, Yang, W.
登録日2020-11-17
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
3KYL
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BU of 3kyl by Molmil
Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA
分子名称: DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*TP*TP*CP*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*G)-3'), MAGNESIUM ION, Telomerase reverse transcriptase
著者Skordalakes, E.
登録日2009-12-06
公開日2010-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.
Nat.Struct.Mol.Biol., 17, 2010
8T2S
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BU of 8t2s by Molmil
Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state
分子名称: AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ...
著者Xu, L, Liu, T, Chung, K, Pyle, A.M.
登録日2023-06-06
公開日2023-11-22
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
8T2R
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BU of 8t2r by Molmil
Structure of a group II intron ribonucleoprotein in the pre-ligation (pre-2F) state
分子名称: 5'exon, AMMONIUM ION, CALCIUM ION, ...
著者Xu, L, Liu, T, Chung, K, Pyle, A.M.
登録日2023-06-06
公開日2023-11-22
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
8T2T
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BU of 8t2t by Molmil
Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state
分子名称: AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ...
著者Xu, L, Liu, T, Chung, K, Pyle, A.M.
登録日2023-06-06
公開日2023-11-22
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023

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