7KQN

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

Summary for 7KQN

• Entry DOI: 10.2210/pdb7kqn/pdb
• Descriptor: Telomerase reverse transcriptase, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3'), ... (10 entities in total)
• Functional Keywords: rap, repeat addition processivity, dna hairpin, rna template, telomere, tbe, template-boundary element, transferase, transferase-rna-dna complex, transferase/rna/dna
• Biological source: Tribolium castaneum (red flour beetle); More
• Total number of polymer chains: 8
• Total formula weight: 164168.83

Authors

Choi, W.S.,Weng, P.J.,Yang, W. (deposition date: 2020-11-17, release date: 2022-03-23, Last modification date: 2023-10-18)

• Primary citation: Choi, W.S.,Weng, P.J.,Yang, W.; Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.; Proc.Natl.Acad.Sci.USA, 119:-, 2022; PubMed: 34969861; DOI: 10.1073/pnas.2116159118

Experimental method

X-RAY DIFFRACTION (2.02 Å)