7KQN

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Telomerase reverse transcriptase	polymer	596	70588.7	2	UniProt (Q0QHL8) Pfam (PF12009) Pfam (PF00078) Pfam (PF17984) In PDB	Tribolium castaneum (red flour beetle)
2	B, E	RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3')	polymer	18	5802.6	2		Tribolium castaneum
3	C, F	DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3')	polymer	7	2098.4	2		Tribolium castaneum
4	I, J	DNA (5'-D(*TP*TP*CP*TP*TP*TP*G)-3')	polymer	7	2094.4	2		Tribolium castaneum
5	D, A, E	1,2-ETHANEDIOL	non-polymer		62.1	21	Chemie (EDO)
6	A	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
7	D, A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
8	D, A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
9	D, A	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (DGT)
10		water	water		18.0	1304	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	161168.2
Non-Polymers*	Number of molecules	29
	Total formula weight	3000.7
All*	Total formula weight	164168.8

*Water molecules are not included.