7KQN

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Telomerase reverse transcriptase	polymer	596	70588.7	2	UniProt (Q0QHL8) Pfam (PF12009) Pfam (PF00078) Pfam (PF17984)	Tribolium castaneum (red flour beetle)
2	B, E (B, E)	RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3')	polymer	18	5802.6	2		Tribolium castaneum
3	C, F (C, F)	DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3')	polymer	7	2098.4	2		Tribolium castaneum
4	G, H (I, J)	DNA (5'-D(*TP*TP*CP*TP*TP*TP*G)-3')	polymer	7	2094.4	2		Tribolium castaneum
5	AA, BA, CA, DA, EA... (D, A, E)	1,2-ETHANEDIOL	non-polymer		62.1	21	Chemie (EDO)
6	S, T (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES) PubChem (4478249)
7	HA, U (D, A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG) PubChem (8117)
8	IA, V (D, A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
9	JA, W (D, A)	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (DGT) PubChem (177678918) PubChem (136110594) PubChem (135398599) PubChem (135402022) PubChem (135566345) PubChem (136254580) PubChem (136633653) PubChem (136828797) PubChem (136828798) PubChem (137226754) PubChem (137257907) PubChem (171699498)
10	LA, MA, NA, OA, PA... (A, B, C, D, E...)	water	water		18.0	1304	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	161168.2
Non-Polymers*	Number of molecules	29
	Total formula weight	3000.7
All*	Total formula weight	164168.8

*Water molecules are not included.