7QXS

Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)

Summary for 7QXS

• Entry DOI: 10.2210/pdb7qxs/pdb
• Related: 7QXA 7QXB
• EMDB information: 14196 14197 14198 14199
• Descriptor: Telomerase reverse transcriptase, RNA (256-MER), Histone H2A, ... (7 entities in total)
• Functional Keywords: reverse transcriptase, ribonucleoprotein, telomerase, telomere, dna binding protein, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 434924.07

Authors

Sekne, Z.,Ghanim, G.E.,van Roon, A.M.M.,Nguyen, T.H.D. (deposition date: 2022-01-27, release date: 2022-03-02, Last modification date: 2022-03-23)

• Primary citation: Sekne, Z.,Ghanim, G.E.,van Roon, A.M.,Nguyen, T.H.D.; Structural basis of human telomerase recruitment by TPP1-POT1.; Science, 375:1173-1176, 2022; PubMed: 35201900; DOI: 10.1126/science.abn6840

Experimental method

ELECTRON MICROSCOPY (3.91 Å)