7QXS
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Telomerase reverse transcriptase | polymer | 1132 | 127195.8 | 1 | UniProt (O14746) Pfam (PF12009) Pfam (PF00078) Pfam (PF21399) | Homo sapiens (human) | HEST2,Telomerase catalytic subunit,Telomerase-associated protein 2,TP2 |
| 2 | B (B) | RNA (256-MER) | polymer | 451 | 145477.8 | 1 | GenBank (NR_001566) | Homo sapiens (human) | |
| 3 | C (L) | Histone H2A | polymer | 130 | 14140.6 | 1 | UniProt (B2R5B3) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | |
| 4 | D (M) | Histone H2B | polymer | 166 | 18074.9 | 1 | UniProt (B4DR52) Pfam (PF00125) | Homo sapiens (human) | |
| 5 | E (N) | Telomeric DNA | polymer | 30 | 9501.1 | 1 | Homo sapiens | ||
| 6 | F (O) | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a | polymer | 458 | 49013.1 | 1 | UniProt (A0A590TQL1) Pfam (PF10341) UniProt (by SIFTS) (Q96AP0) | Homo sapiens (human) | Adrenocortical dysplasia protein homolog |
| 7 | G (P) | Protection of telomeres protein 1 | polymer | 634 | 71520.8 | 1 | UniProt (Q9NUX5) Pfam (PF21375) Pfam (PF02765) Pfam (PF16686) | Homo sapiens (human) | hPot1,POT1-like telomere end-binding protein |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 434924.1 | |
| All* | Total formula weight | 434924.1 |
