PDB: 400 件ウェブページステータス検索Chemie searchBIRD

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7ZG0	Murine IL-27 in complex with IL-27Ra and a non-competing Nb 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... 著者 Skladanowska, K, Bloch, Y, Savvides, S.N. 登録日 2022-04-01 公開日 2022-11-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27. Cell Rep, 41, 2022
7ZCB	Human Pikachurin/EGFLAM N-terminal Fibronectin-III (1-2) domains 分子名称: CHLORIDE ION, Pikachurin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Pantalone, S, Savino, S, Viti, L.V, Forneris, F. 登録日 2022-03-26 公開日 2023-07-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179. Sci.Signal., 16, 2023
7U7N	IL-27 quaternary receptor signaling complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... 著者 Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. 登録日 2022-03-07 公開日 2022-05-25 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
7U6E	Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM462 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IM462, ... 著者 Kirk, N.S, Lawrence, M.C. 登録日 2022-03-03 公開日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Activation of the human insulin receptor by non-insulin-related peptides Nat Commun, 13, 2022
7U6D	Head region of insulin receptor ectodomain (A-isoform) bound to the non-insulin agonist IM459 分子名称: IM459, Isoform Short of Insulin receptor 著者 Kirk, N.S, Lawrence, M.C. 登録日 2022-03-03 公開日 2022-10-05 実験手法 ELECTRON MICROSCOPY (5.03 Å) 主引用文献 Activation of the human insulin receptor by non-insulin-related peptides Nat Commun, 13, 2022
7Z0L	IL-27 signalling complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... 著者 Jin, Y, Gardner, S, Bubeck, D. 登録日 2022-02-23 公開日 2022-07-27 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural insights into the assembly and activation of the IL-27 signaling complex. Embo Rep., 23, 2022
7U08	Structure of CD148 fibronectin type III domain 1 and 2 分子名称: PLATINUM (II) ION, Receptor-type tyrosine-protein phosphatase eta 著者 Zhou, D, Zhu, J. 登録日 2022-02-17 公開日 2023-02-22 実験手法 X-RAY DIFFRACTION (3.30691743 Å) 主引用文献 Structure of CD148 fibronectin type III domain 1 and 2 To Be Published
7TYJ	Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied 分子名称: Insulin receptor-related protein 著者 Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. 登録日 2022-02-13 公開日 2023-02-15 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
7TYK	Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry 分子名称: Insulin receptor-related protein 著者 Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. 登録日 2022-02-13 公開日 2023-02-15 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
7TYM	Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry 分子名称: Insulin receptor-related protein 著者 Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. 登録日 2022-02-13 公開日 2023-02-15 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
7QID	tentative model of the human insulin receptor ectodomain bound by three insulin 分子名称: Insulin, Insulin receptor, Isoform Short of Insulin receptor 著者 Gutman, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. 登録日 2021-12-14 公開日 2022-02-02 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain J Cell Biol, 219, 2020
7STJ	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STK	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STI	Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STH	Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) 分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7S8V	Leg region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-09-20 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.73 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
7S7K	Crystal structure of the EphB2 extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ... 著者 Xu, Y, Xu, K, Nikolov, D.B. 登録日 2021-09-16 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism. Int J Mol Sci, 22, 2021
7S0Q	Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... 著者 Xu, Y, Lawrence, M.C. 登録日 2021-08-30 公開日 2022-07-06 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor. Structure, 30, 2022
7PG2	Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1 分子名称: Insulin, Isoform Short of Insulin receptor 著者 Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. 登録日 2021-08-12 公開日 2022-02-02 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. J.Mol.Biol., 434, 2022

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