3UK6
 
 | | Crystal Structure of the Tip48 (Tip49b) hexamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 2 | | 著者 | Petukhov, M, Dagkessamanskaja, A, Bommer, M, Barrett, T, Tsaneva, I, Yakimov, A, Queval, R, Shvetsov, A, Khodorkovskiy, M, Kas, E, Grigoriev, M. | | 登録日 | 2011-11-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Large-Scale Conformational Flexibility Determines the Properties of AAA+ TIP49 ATPases.
Structure, 20, 2012
|
|
3UNB
 | | Mouse constitutive 20S proteasome in complex with PR-957 | | 分子名称: | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. | | 登録日 | 2011-11-15 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
|
|
3QNT
 | | NPC1L1 (NTD) Structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1-like protein 1 | | 著者 | Kwon, H.J. | | 登録日 | 2011-02-09 | | 公開日 | 2011-05-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | The Structure of the NPC1L1 N-Terminal Domain in a Closed Conformation.
Plos One, 6, 2011
|
|
4L1W
 | | Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 in Complex with NADP+ and Progesterone | | 分子名称: | Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ... | | 著者 | Zhang, B, Hu, X.-J, Lin, S.-X. | | 登録日 | 2013-06-03 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity
J.Steroid Biochem.Mol.Biol., 141, 2014
|
|
2F4O
 | | The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs | | 分子名称: | CHLORIDE ION, PHQ-VAL-ALA-ASP-CF0, XP-C repair complementing complex 58 kDa protein, ... | | 著者 | Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H. | | 登録日 | 2005-11-23 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
J.Biol.Chem., 281, 2006
|
|
2LLH
 | | NMR structure of Npm1_c70 | | 分子名称: | Nucleophosmin | | 著者 | Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M. | | 登録日 | 2011-11-09 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter.
J.Biol.Chem., 287, 2012
|
|
3UF1
 | | Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B | | 分子名称: | Vimentin | | 著者 | Kuzin, A, Abashidze, M, Vorobiev, S.M, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-10-31 | | 公開日 | 2011-11-30 | | 最終更新日 | 2013-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
J.Biol.Chem., 287, 2012
|
|
3V6C
 | | Crystal Structure of USP2 in complex with mutated ubiquitin | | 分子名称: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | | 著者 | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-19 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of USP2 in complex with mutated ubiquitin
To be Published
|
|
2JFM
 | | CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (UNLIGANDED FORM) | | 分子名称: | 1,2-ETHANEDIOL, STE20-LIKE SERINE-THREONINE KINASE | | 著者 | Pike, A.C.W, Rellos, P, Fedorov, O, Keates, T, Salah, E, Savitsky, P, Papagrigoriou, E, Bunkoczi, G, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | | 登録日 | 2007-02-02 | | 公開日 | 2007-02-27 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
|
|
2CRZ
 | |
2CR3
 | |
3V6E
 | | Crystal Structure of USP2 and a mutant form of Ubiquitin | | 分子名称: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | | 著者 | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-19 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
|
|
2LTO
 | | TDRD3 complex | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Tudor domain-containing protein 3 | | 著者 | Sikorsky, T. | | 登録日 | 2012-05-30 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recognition of asymmetrically dimethylated arginine by TDRD3.
Nucleic Acids Res., 40, 2012
|
|
2LSY
 | |
2FWO
 | |
2LUE
 | | LC3B OPTN-LIR Ptot complex structure | | 分子名称: | Microtubule-associated proteins 1A/1B light chain 3B, Optineurin | | 著者 | Rogov, V.V, Rozenknop, A, Loehr, F, Guentert, P, Doetsch, V. | | 登録日 | 2012-06-13 | | 公開日 | 2013-07-17 | | 最終更新日 | 2022-08-24 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella.
Biochem.J., 454, 2013
|
|
2FSZ
 | |
5X9C
 | |
6E5X
 | | Crystal structure of Ebola virus VP30 C-terminus/RBBP6 peptide complex | | 分子名称: | CALCIUM ION, E3 ubiquitin-protein ligase RBBP6, Minor nucleoprotein VP30 | | 著者 | Liu, D, Small, G.I, Leung, D.W, Amarasinghe, G.K. | | 登録日 | 2018-07-23 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
Cell, 175, 2018
|
|
5XA0
 | | Crystal structure of inositol 1,4,5-trisphosphate receptor cytosolic domain | | 分子名称: | Inositol 1,4,5-trisphosphate receptor type 1 | | 著者 | Hamada, K, Miyatake, H, Terauchi, A, Mikoshiba, K. | | 登録日 | 2017-03-10 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (5.812 Å) | | 主引用文献 | IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4HNM
 | | Crystal structure of human catenin-beta-like 1 56 kDa fragment | | 分子名称: | Beta-catenin-like protein 1 | | 著者 | Du, Z, Huang, X, Wang, G, Wu, Y. | | 登録日 | 2012-10-19 | | 公開日 | 2013-07-31 | | 最終更新日 | 2013-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.9001 Å) | | 主引用文献 | The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
6ED1
 | | Bacteroides dorei Beta-glucuronidase | | 分子名称: | Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION | | 著者 | Biernat, K.A, Redinbo, M.R. | | 登録日 | 2018-08-08 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
|
|
5XA1
 | | Crystal structure of inositol 1,4,5-trisphosphate receptor cytosolic domain with inositol 1,4,5-trisphosphate | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 | | 著者 | Hamada, K, Miyatake, H, Terauchi, A, Mikoshiba, K. | | 登録日 | 2017-03-10 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (6.204 Å) | | 主引用文献 | IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6EMM
 | | 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with Salicylic acid | | 分子名称: | 17-beta-hydroxysteroid dehydrogenase 14, 2-HYDROXYBENZOIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. | | 登録日 | 2017-10-02 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | X-ray Crystallographic Fragment screening and Hit Optimization
To Be Published
|
|
5XI4
 | | BRD4 bound with compound Bdi4 | | 分子名称: | (3~{S})-4-cyclopropyl-1,3-dimethyl-6-[[(1~{S})-1-(4-methylphenyl)ethyl]amino]-3~{H}-quinoxalin-2-one, Bromodomain-containing protein 4 | | 著者 | Xiong, B, Cao, D, Li, Y. | | 登録日 | 2017-04-25 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.486 Å) | | 主引用文献 | BRD4 bound with compound Bdi4
To Be Published
|
|
