3UNB

Mouse constitutive 20S proteasome in complex with PR-957

Summary for 3UNB

• Entry DOI: 10.2210/pdb3unb/pdb
• Related: 1IRU 1PMA 1RYP 3UN4 3UN8 3UNE 3UNF 3UNH
• Related PRD ID: PRD_000991
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-2, Proteasome subunit beta type-5, ... (16 entities in total)
• Functional Keywords: 20s proteasome comprises 28 subunits; each subunit adopts the fold of an antiparallel beta-sheet flanked by helices, protease, regulatory complexes, covalent binding of pr-957 to all active sites, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm: P49722 Q9R1P3 O55234 O09061 Q60692 Q9R1P0 Q9Z2U0 Q9Z2U1 Q9R1P4 O70435 Q9QUM9 P70195 Q9R1P1; Cytoplasm (By similarity): P99026
• Total number of polymer chains: 56
• Total formula weight: 1442672.20

Authors

Huber, E.,Basler, M.,Schwab, R.,Heinemeyer, W.,Kirk, C.,Groettrup, M.,Groll, M. (deposition date: 2011-11-15, release date: 2012-02-29, Last modification date: 2023-09-13)

• Primary citation: Huber, E.M.,Basler, M.,Schwab, R.,Heinemeyer, W.,Kirk, C.J.,Groettrup, M.,Groll, M.; Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.; Cell(Cambridge,Mass.), 148:727-738, 2012; PubMed: 22341445; DOI: 10.1016/j.cell.2011.12.030

Experimental method

X-RAY DIFFRACTION (2.9 Å)