3UNB
Mouse constitutive 20S proteasome in complex with PR-957
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, CA, O, QA (A, O, c, q) | Proteasome subunit alpha type-2 | polymer | 234 | 25955.6 | 4 | UniProt (P49722) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C3, Multicatalytic endopeptidase complex subunit C3, Proteasome component C3 |
| 2 | B, DA, P, RA (B, P, d, r) | Proteasome subunit alpha type-4 | polymer | 261 | 29512.8 | 4 | UniProt (Q9R1P0) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L |
| 3 | C, EA, Q, SA (C, Q, e, s) | Proteasome subunit alpha type-7 | polymer | 248 | 27839.9 | 4 | UniProt (Q9Z2U0) Pfam (PF00227) Pfam (PF10584) | Mus musculus (mouse) | Proteasome subunit RC6-1 |
| 4 | D, FA, R, TA (D, R, f, t) | Proteasome subunit alpha type-5 | polymer | 241 | 26436.0 | 4 | UniProt (Q9Z2U1) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain |
| 5 | E, GA, S, UA (E, S, g, u) | Proteasome subunit alpha type-1 | polymer | 263 | 29586.6 | 4 | UniProt (Q9R1P4) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain |
| 6 | F, HA, T, VA (F, T, h, v) | Proteasome subunit alpha type-3 | polymer | 255 | 28442.2 | 4 | UniProt (O70435) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C8, Multicatalytic endopeptidase complex subunit C8, Proteasome component C8, Proteasome subunit K |
| 7 | G, IA, U, WA (G, U, i, w) | Proteasome subunit alpha type-6 | polymer | 246 | 27405.4 | 4 | UniProt (Q9QUM9) Pfam (PF10584) Pfam (PF00227) | Mus musculus (mouse) | Macropain iota chain, Multicatalytic endopeptidase complex iota chain, Proteasome iota chain |
| 8 | H, JA, V, XA (H, V, j, x) | Proteasome subunit beta type-7 | polymer | 234 | 25280.0 | 4 | UniProt (P70195) Pfam (PF00227) Pfam (PF12465) | Mus musculus (mouse) | Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome subunit Z |
| 9 | I, KA, W, YA (I, W, k, y) | Proteasome subunit beta type-3 | polymer | 205 | 22988.9 | 4 | UniProt (Q9R1P1) Pfam (PF00227) | Mus musculus (mouse) | Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain |
| 10 | J, LA, X, ZA (J, X, l, z) | Proteasome subunit beta type-2 | polymer | 201 | 22935.4 | 4 | UniProt (Q9R1P3) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C7-I, Multicatalytic endopeptidase complex subunit C7-I, Proteasome component C7-I |
| 11 | AB, K, MA, Y (K, Y, m, 1) | Proteasome subunit beta type-5 | polymer | 205 | 22554.5 | 4 | UniProt (O55234) Pfam (PF00227) | Mus musculus (mouse) | Macropain epsilon chain, Multicatalytic endopeptidase complex epsilon chain, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit X |
| 12 | BB, L, NA, Z (L, Z, n, 2) | Proteasome subunit beta type-1 | polymer | 213 | 23577.0 | 4 | UniProt (O09061) Pfam (PF00227) | Mus musculus (mouse) | Macropain subunit C5, Multicatalytic endopeptidase complex subunit C5, Proteasome component C5, Proteasome gamma chain |
| 13 | AA, CB, M, OA (M, a, o, 3) | Proteasome subunit beta type-4 | polymer | 219 | 24384.7 | 4 | UniProt (P99026) Pfam (PF00227) | Mus musculus (mouse) | Low molecular mass protein 3, Macropain beta chain, Multicatalytic endopeptidase complex beta chain, Proteasome beta chain, Proteasome chain 3 |
| 14 | BA, DB, N, PA (N, b, p, 4) | Proteasome subunit beta type-6 | polymer | 205 | 22014.9 | 4 | UniProt (Q60692) Pfam (PF00227) | Mus musculus (mouse) | Low molecular mass protein 19, Macropain delta chain, Multicatalytic endopeptidase complex delta chain, Proteasome delta chain, Proteasome subunit Y |
| 15 | EB, FB, GB, HB, IB... (H, K, N, V, Y...) | 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol | non-polymer | 584.7 | 12 | BIRD (PRD_000991) Chemie (04C) | |||
| 16 | AC, AD, BC, BD, CC... (K, k, L, l, M...) | water | water | 18.0 | 1480 | Chemie (HOH) |
Sequence modifications
A, O, c, q: 0 - 233 (UniProt: P49722)
C, Q, e, s: 0 - 247 (UniProt: Q9Z2U0)
| PDB | External Database | Details |
|---|---|---|
| Lys 2 | Glu 3 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 45 | Glu 46 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 56 |
| Total formula weight | 1435655.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 7016.4 | |
| All* | Total formula weight | 1442672.2 |
