3UNB

Mouse constitutive 20S proteasome in complex with PR-957

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0004298	molecular_function	threonine-type endopeptidase activity
1	0005839	cellular_component	proteasome core complex
1	0051603	biological_process	proteolysis involved in protein catabolic process
2	0005839	cellular_component	proteasome core complex
2	0051603	biological_process	proteolysis involved in protein catabolic process
3	0005839	cellular_component	proteasome core complex
3	0051603	biological_process	proteolysis involved in protein catabolic process
4	0004298	molecular_function	threonine-type endopeptidase activity
4	0005839	cellular_component	proteasome core complex
4	0051603	biological_process	proteolysis involved in protein catabolic process
A	0000502	cellular_component	proteasome complex
A	0000932	cellular_component	P-body
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005839	cellular_component	proteasome core complex
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0009615	biological_process	response to virus
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0051603	biological_process	proteolysis involved in protein catabolic process
B	0000502	cellular_component	proteasome complex
B	0000932	cellular_component	P-body
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005839	cellular_component	proteasome core complex
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0019773	cellular_component	proteasome core complex, alpha-subunit complex
B	0032991	cellular_component	protein-containing complex
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0051603	biological_process	proteolysis involved in protein catabolic process
C	0000502	cellular_component	proteasome complex
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005839	cellular_component	proteasome core complex
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0042802	molecular_function	identical protein binding
C	0051603	biological_process	proteolysis involved in protein catabolic process
D	0000502	cellular_component	proteasome complex
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005839	cellular_component	proteasome core complex
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0019773	cellular_component	proteasome core complex, alpha-subunit complex
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0051603	biological_process	proteolysis involved in protein catabolic process
E	0000502	cellular_component	proteasome complex
E	0001530	molecular_function	lipopolysaccharide binding
E	0002376	biological_process	immune system process
E	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005839	cellular_component	proteasome core complex
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0051603	biological_process	proteolysis involved in protein catabolic process
F	0000502	cellular_component	proteasome complex
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005839	cellular_component	proteasome core complex
F	0006511	biological_process	ubiquitin-dependent protein catabolic process
F	0019773	cellular_component	proteasome core complex, alpha-subunit complex
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0051603	biological_process	proteolysis involved in protein catabolic process
G	0000502	cellular_component	proteasome complex
G	0000932	cellular_component	P-body
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005839	cellular_component	proteasome core complex
G	0005840	cellular_component	ribosome
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0007519	biological_process	skeletal muscle tissue development
G	0016363	cellular_component	nuclear matrix
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030016	cellular_component	myofibril
G	0030017	cellular_component	sarcomere
G	0051059	molecular_function	NF-kappaB binding
G	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
G	0051603	biological_process	proteolysis involved in protein catabolic process
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005839	cellular_component	proteasome core complex
H	0051603	biological_process	proteolysis involved in protein catabolic process
I	0000502	cellular_component	proteasome complex
I	0004175	molecular_function	endopeptidase activity
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005839	cellular_component	proteasome core complex
I	0019774	cellular_component	proteasome core complex, beta-subunit complex
I	0030163	biological_process	protein catabolic process
I	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
I	0051603	biological_process	proteolysis involved in protein catabolic process
J	0000502	cellular_component	proteasome complex
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005839	cellular_component	proteasome core complex
J	0010498	biological_process	proteasomal protein catabolic process
J	0014070	biological_process	response to organic cyclic compound
J	0019774	cellular_component	proteasome core complex, beta-subunit complex
J	0051603	biological_process	proteolysis involved in protein catabolic process
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005839	cellular_component	proteasome core complex
K	0051603	biological_process	proteolysis involved in protein catabolic process
L	0005839	cellular_component	proteasome core complex
L	0051603	biological_process	proteolysis involved in protein catabolic process
M	0005839	cellular_component	proteasome core complex
M	0051603	biological_process	proteolysis involved in protein catabolic process
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005839	cellular_component	proteasome core complex
N	0051603	biological_process	proteolysis involved in protein catabolic process
O	0000502	cellular_component	proteasome complex
O	0000932	cellular_component	P-body
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005839	cellular_component	proteasome core complex
O	0006511	biological_process	ubiquitin-dependent protein catabolic process
O	0009615	biological_process	response to virus
O	0019773	cellular_component	proteasome core complex, alpha-subunit complex
O	0051603	biological_process	proteolysis involved in protein catabolic process
P	0000502	cellular_component	proteasome complex
P	0000932	cellular_component	P-body
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005839	cellular_component	proteasome core complex
P	0006511	biological_process	ubiquitin-dependent protein catabolic process
P	0019773	cellular_component	proteasome core complex, alpha-subunit complex
P	0032991	cellular_component	protein-containing complex
P	0043231	cellular_component	intracellular membrane-bounded organelle
P	0051603	biological_process	proteolysis involved in protein catabolic process
Q	0000502	cellular_component	proteasome complex
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005839	cellular_component	proteasome core complex
Q	0006511	biological_process	ubiquitin-dependent protein catabolic process
Q	0019773	cellular_component	proteasome core complex, alpha-subunit complex
Q	0042802	molecular_function	identical protein binding
Q	0051603	biological_process	proteolysis involved in protein catabolic process
R	0000502	cellular_component	proteasome complex
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005839	cellular_component	proteasome core complex
R	0006511	biological_process	ubiquitin-dependent protein catabolic process
R	0019773	cellular_component	proteasome core complex, alpha-subunit complex
R	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
R	0051603	biological_process	proteolysis involved in protein catabolic process
S	0000502	cellular_component	proteasome complex
S	0001530	molecular_function	lipopolysaccharide binding
S	0002376	biological_process	immune system process
S	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005813	cellular_component	centrosome
S	0005829	cellular_component	cytosol
S	0005839	cellular_component	proteasome core complex
S	0006511	biological_process	ubiquitin-dependent protein catabolic process
S	0019773	cellular_component	proteasome core complex, alpha-subunit complex
S	0051603	biological_process	proteolysis involved in protein catabolic process
T	0000502	cellular_component	proteasome complex
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005839	cellular_component	proteasome core complex
T	0006511	biological_process	ubiquitin-dependent protein catabolic process
T	0019773	cellular_component	proteasome core complex, alpha-subunit complex
T	0031625	molecular_function	ubiquitin protein ligase binding
T	0051603	biological_process	proteolysis involved in protein catabolic process
U	0000502	cellular_component	proteasome complex
U	0000932	cellular_component	P-body
U	0003723	molecular_function	RNA binding
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005839	cellular_component	proteasome core complex
U	0005840	cellular_component	ribosome
U	0006511	biological_process	ubiquitin-dependent protein catabolic process
U	0007519	biological_process	skeletal muscle tissue development
U	0016363	cellular_component	nuclear matrix
U	0019773	cellular_component	proteasome core complex, alpha-subunit complex
U	0030016	cellular_component	myofibril
U	0030017	cellular_component	sarcomere
U	0051059	molecular_function	NF-kappaB binding
U	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
U	0051603	biological_process	proteolysis involved in protein catabolic process
V	0004298	molecular_function	threonine-type endopeptidase activity
V	0005839	cellular_component	proteasome core complex
V	0051603	biological_process	proteolysis involved in protein catabolic process
W	0000502	cellular_component	proteasome complex
W	0004175	molecular_function	endopeptidase activity
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005839	cellular_component	proteasome core complex
W	0019774	cellular_component	proteasome core complex, beta-subunit complex
W	0030163	biological_process	protein catabolic process
W	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
W	0051603	biological_process	proteolysis involved in protein catabolic process
X	0000502	cellular_component	proteasome complex
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005839	cellular_component	proteasome core complex
X	0010498	biological_process	proteasomal protein catabolic process
X	0014070	biological_process	response to organic cyclic compound
X	0019774	cellular_component	proteasome core complex, beta-subunit complex
X	0051603	biological_process	proteolysis involved in protein catabolic process
Y	0004298	molecular_function	threonine-type endopeptidase activity
Y	0005839	cellular_component	proteasome core complex
Y	0051603	biological_process	proteolysis involved in protein catabolic process
Z	0005839	cellular_component	proteasome core complex
Z	0051603	biological_process	proteolysis involved in protein catabolic process
a	0005839	cellular_component	proteasome core complex
a	0051603	biological_process	proteolysis involved in protein catabolic process
b	0004298	molecular_function	threonine-type endopeptidase activity
b	0005839	cellular_component	proteasome core complex
b	0051603	biological_process	proteolysis involved in protein catabolic process
c	0000502	cellular_component	proteasome complex
c	0000932	cellular_component	P-body
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005839	cellular_component	proteasome core complex
c	0006511	biological_process	ubiquitin-dependent protein catabolic process
c	0009615	biological_process	response to virus
c	0019773	cellular_component	proteasome core complex, alpha-subunit complex
c	0051603	biological_process	proteolysis involved in protein catabolic process
d	0000502	cellular_component	proteasome complex
d	0000932	cellular_component	P-body
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005839	cellular_component	proteasome core complex
d	0006511	biological_process	ubiquitin-dependent protein catabolic process
d	0019773	cellular_component	proteasome core complex, alpha-subunit complex
d	0032991	cellular_component	protein-containing complex
d	0043231	cellular_component	intracellular membrane-bounded organelle
d	0051603	biological_process	proteolysis involved in protein catabolic process
e	0000502	cellular_component	proteasome complex
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005839	cellular_component	proteasome core complex
e	0006511	biological_process	ubiquitin-dependent protein catabolic process
e	0019773	cellular_component	proteasome core complex, alpha-subunit complex
e	0042802	molecular_function	identical protein binding
e	0051603	biological_process	proteolysis involved in protein catabolic process
f	0000502	cellular_component	proteasome complex
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005839	cellular_component	proteasome core complex
f	0006511	biological_process	ubiquitin-dependent protein catabolic process
f	0019773	cellular_component	proteasome core complex, alpha-subunit complex
f	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
f	0051603	biological_process	proteolysis involved in protein catabolic process
g	0000502	cellular_component	proteasome complex
g	0001530	molecular_function	lipopolysaccharide binding
g	0002376	biological_process	immune system process
g	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005813	cellular_component	centrosome
g	0005829	cellular_component	cytosol
g	0005839	cellular_component	proteasome core complex
g	0006511	biological_process	ubiquitin-dependent protein catabolic process
g	0019773	cellular_component	proteasome core complex, alpha-subunit complex
g	0051603	biological_process	proteolysis involved in protein catabolic process
h	0000502	cellular_component	proteasome complex
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005839	cellular_component	proteasome core complex
h	0006511	biological_process	ubiquitin-dependent protein catabolic process
h	0019773	cellular_component	proteasome core complex, alpha-subunit complex
h	0031625	molecular_function	ubiquitin protein ligase binding
h	0051603	biological_process	proteolysis involved in protein catabolic process
i	0000502	cellular_component	proteasome complex
i	0000932	cellular_component	P-body
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005839	cellular_component	proteasome core complex
i	0005840	cellular_component	ribosome
i	0006511	biological_process	ubiquitin-dependent protein catabolic process
i	0007519	biological_process	skeletal muscle tissue development
i	0016363	cellular_component	nuclear matrix
i	0019773	cellular_component	proteasome core complex, alpha-subunit complex
i	0030016	cellular_component	myofibril
i	0030017	cellular_component	sarcomere
i	0051059	molecular_function	NF-kappaB binding
i	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
i	0051603	biological_process	proteolysis involved in protein catabolic process
j	0004298	molecular_function	threonine-type endopeptidase activity
j	0005839	cellular_component	proteasome core complex
j	0051603	biological_process	proteolysis involved in protein catabolic process
k	0000502	cellular_component	proteasome complex
k	0004175	molecular_function	endopeptidase activity
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005839	cellular_component	proteasome core complex
k	0019774	cellular_component	proteasome core complex, beta-subunit complex
k	0030163	biological_process	protein catabolic process
k	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
k	0051603	biological_process	proteolysis involved in protein catabolic process
l	0000502	cellular_component	proteasome complex
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005839	cellular_component	proteasome core complex
l	0010498	biological_process	proteasomal protein catabolic process
l	0014070	biological_process	response to organic cyclic compound
l	0019774	cellular_component	proteasome core complex, beta-subunit complex
l	0051603	biological_process	proteolysis involved in protein catabolic process
m	0004298	molecular_function	threonine-type endopeptidase activity
m	0005839	cellular_component	proteasome core complex
m	0051603	biological_process	proteolysis involved in protein catabolic process
n	0005839	cellular_component	proteasome core complex
n	0051603	biological_process	proteolysis involved in protein catabolic process
o	0005839	cellular_component	proteasome core complex
o	0051603	biological_process	proteolysis involved in protein catabolic process
p	0004298	molecular_function	threonine-type endopeptidase activity
p	0005839	cellular_component	proteasome core complex
p	0051603	biological_process	proteolysis involved in protein catabolic process
q	0000502	cellular_component	proteasome complex
q	0000932	cellular_component	P-body
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005839	cellular_component	proteasome core complex
q	0006511	biological_process	ubiquitin-dependent protein catabolic process
q	0009615	biological_process	response to virus
q	0019773	cellular_component	proteasome core complex, alpha-subunit complex
q	0051603	biological_process	proteolysis involved in protein catabolic process
r	0000502	cellular_component	proteasome complex
r	0000932	cellular_component	P-body
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005839	cellular_component	proteasome core complex
r	0006511	biological_process	ubiquitin-dependent protein catabolic process
r	0019773	cellular_component	proteasome core complex, alpha-subunit complex
r	0032991	cellular_component	protein-containing complex
r	0043231	cellular_component	intracellular membrane-bounded organelle
r	0051603	biological_process	proteolysis involved in protein catabolic process
s	0000502	cellular_component	proteasome complex
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005737	cellular_component	cytoplasm
s	0005829	cellular_component	cytosol
s	0005839	cellular_component	proteasome core complex
s	0006511	biological_process	ubiquitin-dependent protein catabolic process
s	0019773	cellular_component	proteasome core complex, alpha-subunit complex
s	0042802	molecular_function	identical protein binding
s	0051603	biological_process	proteolysis involved in protein catabolic process
t	0000502	cellular_component	proteasome complex
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005839	cellular_component	proteasome core complex
t	0006511	biological_process	ubiquitin-dependent protein catabolic process
t	0019773	cellular_component	proteasome core complex, alpha-subunit complex
t	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
t	0051603	biological_process	proteolysis involved in protein catabolic process
u	0000502	cellular_component	proteasome complex
u	0001530	molecular_function	lipopolysaccharide binding
u	0002376	biological_process	immune system process
u	0002862	biological_process	negative regulation of inflammatory response to antigenic stimulus
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005737	cellular_component	cytoplasm
u	0005813	cellular_component	centrosome
u	0005829	cellular_component	cytosol
u	0005839	cellular_component	proteasome core complex
u	0006511	biological_process	ubiquitin-dependent protein catabolic process
u	0019773	cellular_component	proteasome core complex, alpha-subunit complex
u	0051603	biological_process	proteolysis involved in protein catabolic process
v	0000502	cellular_component	proteasome complex
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0005839	cellular_component	proteasome core complex
v	0006511	biological_process	ubiquitin-dependent protein catabolic process
v	0019773	cellular_component	proteasome core complex, alpha-subunit complex
v	0031625	molecular_function	ubiquitin protein ligase binding
v	0051603	biological_process	proteolysis involved in protein catabolic process
w	0000502	cellular_component	proteasome complex
w	0000932	cellular_component	P-body
w	0003723	molecular_function	RNA binding
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005737	cellular_component	cytoplasm
w	0005829	cellular_component	cytosol
w	0005839	cellular_component	proteasome core complex
w	0005840	cellular_component	ribosome
w	0006511	biological_process	ubiquitin-dependent protein catabolic process
w	0007519	biological_process	skeletal muscle tissue development
w	0016363	cellular_component	nuclear matrix
w	0019773	cellular_component	proteasome core complex, alpha-subunit complex
w	0030016	cellular_component	myofibril
w	0030017	cellular_component	sarcomere
w	0051059	molecular_function	NF-kappaB binding
w	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
w	0051603	biological_process	proteolysis involved in protein catabolic process
x	0004298	molecular_function	threonine-type endopeptidase activity
x	0005839	cellular_component	proteasome core complex
x	0051603	biological_process	proteolysis involved in protein catabolic process
y	0000502	cellular_component	proteasome complex
y	0004175	molecular_function	endopeptidase activity
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0005839	cellular_component	proteasome core complex
y	0019774	cellular_component	proteasome core complex, beta-subunit complex
y	0030163	biological_process	protein catabolic process
y	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
y	0051603	biological_process	proteolysis involved in protein catabolic process
z	0000502	cellular_component	proteasome complex
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005737	cellular_component	cytoplasm
z	0005829	cellular_component	cytosol
z	0005839	cellular_component	proteasome core complex
z	0010498	biological_process	proteasomal protein catabolic process
z	0014070	biological_process	response to organic cyclic compound
z	0019774	cellular_component	proteasome core complex, beta-subunit complex
z	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 04C H 301

Chain	Residue
H	THR1
I	ASP124
I	ILE126
H	ARG19
H	ALA20
H	THR21
H	CYS31
H	GLY47
H	THR48
H	ALA49
H	GLY168

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 04C K 301

Chain	Residue
K	THR1
K	ARG19
K	ALA20
K	THR21
K	VAL31
K	LYS33
K	GLY47
K	GLY48
K	ALA49
K	TYR169
L	ASP125

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 04C N 301

Chain	Residue
H	HIS116
N	THR1
N	ARG19
N	THR20
N	THR21
N	THR31
N	LYS33
N	ARG45
N	GLY47
N	SER48
N	ALA49
N	MET95
N	SER130
N	SER169
N	HOH405
N	HOH428

---

site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 04C V 301

Chain	Residue
V	THR1
V	ARG19
V	ALA20
V	THR21
V	CYS31
V	LYS33
V	ALA46
V	GLY47
V	ALA49
V	SER129
V	GLY168
V	HOH403
W	ASP124
W	ILE126

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 04C Y 301

Chain	Residue
Y	THR1
Y	ARG19
Y	ALA20
Y	THR21
Y	VAL31
Y	GLY47
Y	ALA49
Y	SER130
Y	TYR169
Z	ASP125
Z	VAL127

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE 04C b 301

Chain	Residue
V	HIS116
b	THR1
b	ARG19
b	THR20
b	THR21
b	THR31
b	ARG45
b	SER46
b	GLY47
b	SER48
b	ALA49
b	MET95
b	SER130
b	SER169
b	HOH404
b	HOH405
b	HOH407

---

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 04C j 301

Chain	Residue
j	THR1
j	ARG19
j	ALA20
j	THR21
j	CYS31
j	GLY47
j	THR48
j	ALA49
j	THR52
j	GLY168
j	HOH407
k	ASP124
k	ILE126

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 04C m 301

Chain	Residue
m	MET45
m	GLY47
m	GLY48
m	ALA49
m	TYR169
n	ASP125
m	THR1
m	ARG19
m	ALA20
m	THR21
m	VAL31
m	LYS33

---

site_id	AC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE 04C p 301

Chain	Residue
j	HIS116
j	SER118
j	HOH404
p	THR1
p	ARG19
p	THR20
p	THR21
p	THR31
p	LYS33
p	ARG45
p	GLY47
p	SER48
p	ALA49
p	SER130
p	SER169
p	HOH410
p	HOH411

---

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 04C x 301

Chain	Residue
x	THR1
x	ARG19
x	ALA20
x	THR21
x	CYS31
x	ALA46
x	GLY47
x	ALA49
x	GLY168
x	HOH405
y	ASP124
y	ILE126

---

site_id	BC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 04C 1 301

Chain	Residue
1	THR1
1	ARG19
1	ALA20
1	THR21
1	VAL31
1	GLY47
1	GLY48
1	ALA49
1	TYR169
1	HOH416
2	ASP125
2	VAL127

---

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 04C 4 301

Chain	Residue
4	THR1
4	ARG19
4	THR20
4	THR21
4	THR22
4	THR31
4	ARG45
4	SER46
4	GLY47
4	ALA49
4	MET95
4	SER169
x	HIS116
x	HOH419

---

Functional Information from PROSITE/UniProt

site_id	PS00388
Number of Residues	23
Details	PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. FdrhiTiFSPeGRlyQVEYAfkA

Chain	Residue	Details
G	PHE8-ALA30
C	TYR2-ALA24
D	TYR0-ALA22
A	TYR5-ALA27
E	TYR3-ALA25
F	TYR7-ALA29
B	TYR4-ALA26

---

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LGVkFdgGVVIAADmlgsygslarfrnis.RimrvndstmlgasGdyAD

Chain	Residue	Details
a	LEU12-ASP59
2	LEU13-ASP60
b	MET4-ASP51
J	ILE5-ASP52
1	LEU4-ASP51
H	ALA4-ASP51
B	LEU34-ASP81
I	MET11-ASP58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P28072

Chain	Residue	Details
N	THR1
2	SER34
2	SER40
2	SER134
b	THR1
p	THR1
4	THR1
Z	SER40
Z	SER134
n	SER34
n	SER40
n	SER134

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P28072

Chain	Residue	Details
N	THR35
t	SER8
t	SER48
t	SER55
b	THR35
p	THR35
4	THR35
R	SER48
R	SER55
f	SER8
f	SER48
f	SER55

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P20618

Chain	Residue	Details
L	LYS176
q	SER6
q	SER13
q	SER15
Z	LYS176
n	LYS176
2	LYS176
h	LYS205
h	LYS229
v	LYS205
v	LYS229
c	SER15

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000269|PubMed:22556278

Chain	Residue	Details
L	SER30
L	SER181
Z	SER30
Z	SER181
n	SER30
n	SER181
2	SER30
2	SER181

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000269|PubMed:22556278

Chain	Residue	Details
G	SER4
u	LYS112
u	LYS205
U	SER4
i	SER4
w	SER4
S	LYS205
g	LYS112
g	LYS205

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18034455

Chain	Residue	Details
A	TYR75
O	TYR75
c	TYR75
q	TYR75

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P17220

Chain	Residue	Details
A	TYR120
O	TYR120
c	TYR120
q	TYR120

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS170
O	LYS170
c	LYS170
q	LYS170

---