3UNF

Mouse 20S immunoproteasome in complex with PR-957

Summary for 3UNF

Entry DOI	10.2210/pdb3unf/pdb
Related	1IRU 1PMA 1RYP 3UN4 3UN8 3UNB 3UNE
Related PRD ID	PRD_000991
Descriptor	Proteasome subunit alpha type-2, Proteasome subunit beta type-2, Proteasome subunit beta type-8, ... (19 entities in total)
Functional Keywords	proteasome, antigen presentation, drug development, protein degradation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Mus musculus (mouse) More
Cellular location	Cytoplasm: P49722 Q9R1P3 O55234 O09061 Q60692 Q9R1P0 Q9Z2U0 Q9Z2U1 Q9R1P4 O70435 Q9QUM9 P70195 Q9R1P1 Cytoplasm (By similarity): P99026
Total number of polymer chains	28
Total formula weight	722176.82
Authors	Huber, E.,Basler, M.,Schwab, R.,Heinemeyer, W.,Kirk, C.,Groettrup, M.,Groll, M. (deposition date: 2011-11-15, release date: 2012-02-29, Last modification date: 2023-09-13)
Primary citation	Huber, E.M.,Basler, M.,Schwab, R.,Heinemeyer, W.,Kirk, C.J.,Groettrup, M.,Groll, M. Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148:727-738, 2012 Cited by PubMed: 22341445 DOI: 10.1016/j.cell.2011.12.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation