5XA1

Crystal structure of inositol 1,4,5-trisphosphate receptor cytosolic domain with inositol 1,4,5-trisphosphate

Summary for 5XA1

Entry DOI	10.2210/pdb5xa1/pdb
Related	5X9Z 5XA1
Descriptor	Inositol 1,4,5-trisphosphate receptor type 1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (2 entities in total)
Functional Keywords	receptor channel calcium, metal transport
Biological source	Mus musculus (Mouse)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : P11881
Total number of polymer chains	2
Total formula weight	362855.19
Authors	Hamada, K.,Miyatake, H.,Terauchi, A.,Mikoshiba, K. (deposition date: 2017-03-10, release date: 2017-04-19, Last modification date: 2023-11-22)
Primary citation	Hamada, K.,Miyatake, H.,Terauchi, A.,Mikoshiba, K. IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography Proc. Natl. Acad. Sci. U.S.A., 114:4661-4666, 2017 Cited by PubMed: 28416699 DOI: 10.1073/pnas.1701420114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (6.204 Å)

Structure validation