2F4O

The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs

Summary for 2F4O

• Entry DOI: 10.2210/pdb2f4o/pdb
• Related: 2F4M
• Related PRD ID: PRD_000338
• Descriptor: peptide N-glycanase, XP-C repair complementing complex 58 kDa protein, PHQ-VAL-ALA-ASP-CF0, ... (6 entities in total)
• Functional Keywords: glycoproteins, ubiquitin-dependent protein degradation, nucleotide excision repair, peptide:n-glycanase, transglutaminase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus : P54728
• Total number of polymer chains: 3
• Total formula weight: 42690.07

Authors

Zhao, G.,Zhou, X.,Wang, L.,Kisker, C.,Lennarz, W.J.,Schindelin, H. (deposition date: 2005-11-23, release date: 2006-03-07, Last modification date: 2023-08-23)

• Primary citation: Zhao, G.,Zhou, X.,Wang, L.,Li, G.,Kisker, C.,Lennarz, W.J.,Schindelin, H.; Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.; J.Biol.Chem., 281:13751-13761, 2006; PubMed: 16500903; DOI: 10.1074/jbc.M600137200

Experimental method

X-RAY DIFFRACTION (2.26 Å)