PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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2JJI	Endothiapepsin in complex with a gem-diol inhibitor. 分子名称: ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION 著者 Coates, L, Tuan, H.-F, Tomanicek, S.J, Kovalevsky, A, Mustyakimov, M, Erskine, P, Cooper, J. 登録日 2008-04-09 公開日 2008-05-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-Ray Diffraction J.Am.Chem.Soc., 130, 2008
6C23	Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State 分子名称: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... 著者 Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. 登録日 2018-01-05 公開日 2018-01-24 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
2JCG	Apo form of the catabolite control protein A (ccpA) from bacillus megaterium, with the DNA binding domain 分子名称: CALCIUM ION, GLUCOSE-RESISTANCE AMYLASE REGULATOR 著者 Singh, R.K, Panjikar, S, Palm, G.J, Hinrichs, W. 登録日 2006-12-22 公開日 2007-03-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Apo Form of the Catabolite Control Protein a (Ccpa) from Bacillus Megaterium with a DNA-Binding Domain. Acta Crystallogr.,Sect.F, 63, 2007
5FAJ	Alanine Racemase from Streptomyces coelicolor A3(2) in complex with D-Cycloserine 分子名称: Alanine racemase, CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, ... 著者 Tassoni, R, Pannu, N.S. 登録日 2015-12-11 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural and functional characterization of the alanine racemase from Streptomyces coelicolor A3(2). Biochem. Biophys. Res. Commun., 483, 2017
4R4Y	Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria 分子名称: N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, N-hydroxy-L-asparagine 著者 Sui, L, Damodharan, L, Pande, S, Guo, H.C. 登録日 2014-08-20 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis of a Point Mutation that Causes the Genetic Disease Aspartylglucosaminuria. Structure, 22, 2014
6TSV	Tail of empty GTA particle computed with helical refinement, C6 symmetry 分子名称: Tail tube protein Rcc01691 著者 Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. 登録日 2019-12-21 公開日 2020-07-22 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
4JS7	Crystal structure of D78N mutant apo form of clavibacter michiganensis expansin 分子名称: SULFATE ION, cellulose binding protein 著者 Yennawar, N.H, Yennawar, H.P, Georgelis, N, Cosgrove, D.J. 登録日 2013-03-22 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Crystal structure of wild type and d78n mutant Clavibacter michiganensis expansin, in apo form and in complex with oligosaccharides To be Published
6TSW	Isometric capsid of empty GTA particle computed with I4(I,n25r) symmetry 分子名称: Major capsid protein Rcc01687 著者 Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. 登録日 2019-12-21 公開日 2020-07-22 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.03 Å) 主引用文献 Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
6STD	SCYTALONE DEHYDRATASE PLUS INHIBITOR 3 分子名称: 2,2-DICHLORO-1-METHANESULFINYL-3-METHYL-CYCLOPROPANECARBOXYLIC ACID [1-(4-BROMO-PHENYL)-ETHYL]-AMIDE, CALCIUM ION, Scytalone dehydratase 著者 Wawrzak, Z, Sandalova, T, Steffens, J.J, Basarab, G.S, Lundqvist, T, Lindqvist, Y, Jordan, D.B. 登録日 1999-02-11 公開日 1999-12-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH. Proteins, 35, 1999
5FYG	Structure of CYP153A from Marinobacter aquaeolei in complex with hydroxydodecanoic acid 分子名称: 12-HYDROXYDODECANOIC ACID, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Danesh-Azari, H.-R, Spandolf, C, Hoffman, S.M, Weissenborn, M, Hauer, B, Grogan, G. 登録日 2016-03-07 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids Chemcatchem, 2016
6SNC	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LNO1 Heavy Chain, ... 著者 Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. 登録日 2019-08-23 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
6CHW	Estrogen Receptor Alpha Y537S covalently bound to antagonist H3B-5942. 分子名称: 1,2-ETHANEDIOL, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, DIMETHYL SULFOXIDE, ... 著者 Larsen, N.A. 登録日 2018-02-23 公開日 2018-03-21 最終更新日 2020-02-26 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer. Cancer Discov, 8, 2018
2KM2	Galectin-1 dimer 分子名称: Galectin-1 著者 Nesmelova, I.V, Ermakova, E, Daragan, V.A, Pang, M, Baum, L.G, Mayo, K.H. 登録日 2009-07-16 公開日 2010-04-14 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Lactose binding to galectin-1 modulates structural dynamics, increases conformational entropy, and occurs with apparent negative cooperativity. J.Mol.Biol., 397, 2010
5FYF	Structure of CYP153A from Marinobacter aquaeolei 分子名称: 1,2-ETHANEDIOL, CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Danesh Azari, H.R, Spandolf, C, Hoffman, S.M, Weissenborn, M, Hauer, B, Grogan, G. 登録日 2016-03-07 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids Chemcatchem, 2016
6SNE	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... 著者 Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. 登録日 2019-08-23 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
3MEB	Structure of cytoplasmic aspartate aminotransferase from giardia lamblia 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-31 公開日 2010-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
4JL4	Crystal structure of the complex between PPARgamma LBD and the ligand LJ570 [(2S)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propanoic acid] 分子名称: (2S)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, R, Capelli, D. 登録日 2013-03-12 公開日 2014-03-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of the First PPAR alpha / gamma Dual Agonist Able To Bind to Canonical and Alternative Sites of PPAR gamma and To Inhibit Its Cdk5-Mediated Phosphorylation. J.Med.Chem., 61, 2018
2IEL	CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus 分子名称: Hypothetical Protein TT0030 著者 Zhu, J, Huang, J, Stepanyuk, G, Chen, L, Chang, J, Zhao, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) 登録日 2006-09-19 公開日 2006-11-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION To be Published
4RJD	TFP bound in alternate orientations to calcium-saturated Calmodulin C-Domains 分子名称: 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CHLORIDE ION, ... 著者 Feldkamp, M.D, Gakhar, L, Pandey, N, Shea, M.A. 登録日 2014-10-08 公開日 2015-08-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin. Proteins, 83, 2015
4RLM	Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with CrystFEL 分子名称: Lysozyme C 著者 Botha, S, Nass, K, Barends, T, Kabsch, W, Latz, B, Dworkowski, F, Foucar, L, Panepucci, E, Wang, M, Shoeman, R, Schlichting, I, Doak, R.B. 登録日 2014-10-17 公開日 2015-02-25 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams. Acta Crystallogr.,Sect.D, 71, 2015
4RMG	Human Sirt2 in complex with SirReal2 and NAD+ 分子名称: 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide, NAD-dependent protein deacetylase sirtuin-2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Rumpf, T, Schiedel, M, Karaman, B, Roessler, C, North, B.J, Lehotzky, A, Olah, J, Ladwein, K.I, Schmidtkunz, K, Gajer, M, Pannek, M, Steegborn, C, Sinclair, D.A, Gerhardt, S, Ovadi, J, Schutkowski, M, Sippl, W, Einsle, O, Jung, M. 登録日 2014-10-21 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Nat Commun, 6, 2015
3QWQ	Crystal structure of the extracellular domain of the epidermal growth factor receptor in complex with an adnectin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADNECTIN, ... 著者 Sheriff, S. 登録日 2011-02-28 公開日 2012-02-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of adnectin/protein complexes reveal an expanded binding footprint. Structure, 20, 2012
6U28	Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K 分子名称: Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta 著者 Cho, J.H, Zhao, B, Savage, N, Li, P. 登録日 2019-08-19 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc.Natl.Acad.Sci.USA, 117, 2020
4S2U	Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli 分子名称: MAGNESIUM ION, Ribose-phosphate pyrophosphokinase 著者 Timofeev, V.I, Abramchik, Y.A, Muravieva, T.I, Iaroslavtceva, A.K, Stepanenko, V.N, Zhukhlistova, N.E, Esipov, R.S, Kuranova, I.P. 登録日 2015-01-23 公開日 2016-01-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli To be Published
4TN8	Crystal structure of Thermus Thermophilus thioredoxin solved by sulfur SAD using Swiss Light Source data 分子名称: CHLORIDE ION, Thioredoxin 著者 Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) 登録日 2014-06-03 公開日 2014-12-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015

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