2KM2
Galectin-1 dimer
Summary for 2KM2
| Entry DOI | 10.2210/pdb2km2/pdb |
| Descriptor | Galectin-1 (1 entity in total) |
| Functional Keywords | galectin, dimer, lectin, beta-sheet, acetylation, extracellular matrix, secreted, sugar binding protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space, extracellular matrix: P09382 |
| Total number of polymer chains | 2 |
| Total formula weight | 29198.95 |
| Authors | Nesmelova, I.V.,Ermakova, E.,Daragan, V.A.,Pang, M.,Baum, L.G.,Mayo, K.H. (deposition date: 2009-07-16, release date: 2010-04-14, Last modification date: 2024-05-22) |
| Primary citation | Nesmelova, I.V.,Ermakova, E.,Daragan, V.A.,Pang, M.,Menendez, M.,Lagartera, L.,Solis, D.,Baum, L.G.,Mayo, K.H. Lactose binding to galectin-1 modulates structural dynamics, increases conformational entropy, and occurs with apparent negative cooperativity. J.Mol.Biol., 397:1209-1230, 2010 Cited by PubMed: 20184898DOI: 10.1016/j.jmb.2010.02.033 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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