4R4Y

Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria

Summary for 4R4Y

Entry DOI	10.2210/pdb4r4y/pdb
Descriptor	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, N-hydroxy-L-asparagine (3 entities in total)
Functional Keywords	agu structure, autoprocessing, glycosylasparaginase, lysosomal storage disease, pre-autoproteolysis trap, hydrolase
Biological source	Elizabethkingia miricola
Cellular location	Periplasm: Q47898
Total number of polymer chains	2
Total formula weight	64623.45
Authors	Sui, L.,Damodharan, L.,Pande, S.,Guo, H.C. (deposition date: 2014-08-20, release date: 2014-12-17, Last modification date: 2024-02-28)
Primary citation	Sui, L.,Lakshminarasimhan, D.,Pande, S.,Guo, H.C. Structural Basis of a Point Mutation that Causes the Genetic Disease Aspartylglucosaminuria. Structure, 22:1855-1861, 2014 Cited by PubMed: 25456816 DOI: 10.1016/j.str.2014.09.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation