PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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3EF9	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: SULFATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-09-08 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010
3EGH	Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R 分子名称: GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... 著者 Ragusa, M.J, Page, R, Peti, W. 登録日 2008-09-10 公開日 2010-03-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Nat.Struct.Mol.Biol., 17, 2010
3NTD	Structure of the Shewanella loihica PV-4 NADH-dependent persulfide reductase C531S Mutant 分子名称: CHLORIDE ION, COENZYME A, FAD-dependent pyridine nucleotide-disulphide oxidoreductase, ... 著者 Sazinsky, M.H, Warner, M.D, Lukose, V, Lee, K.H, Crane, E.J. 登録日 2010-07-03 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Characterization of an NADH-Dependent Persulfide Reductase from Shewanella loihica PV-4: Implications for the Mechanism of Sulfur Respiration via FAD-Dependent Enzymes . Biochemistry, 50, 2010
3EPB	Human AdoMetDC E256Q mutant complexed with putrescine 分子名称: 1,4-DIAMINOBUTANE, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ... 著者 Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E. 登録日 2008-09-29 公開日 2008-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase. Biochemistry, 47, 2008
4MCB	H.influenzae TrmD in complex with N-(4-{[(1H-IMIDAZOL-2-YLMETHYL)AMINO]METHYL}BENZYL)-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE 分子名称: ACETATE ION, GLYCEROL, N-(4-{[(1H-imidazol-2-ylmethyl)amino]methyl}benzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide, ... 著者 Olivier, N.B, Hill, P. 登録日 2013-08-21 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Selective Inhibitors of Bacterial t-RNA-(N(1)G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain. J.Med.Chem., 56, 2013
3EPP	Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin 分子名称: SINEFUNGIN, mRNA cap guanine-N7 methyltransferase 著者 Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) 登録日 2008-09-29 公開日 2008-10-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin. To be Published
2IG7	Crystal structure of Human Choline Kinase B 分子名称: Choline/ethanolamine kinase, UNKNOWN ATOM OR ION 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-09-22 公開日 2006-10-10 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Human Choline Kinase B To be Published
3EQD	X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a binary complex with ATP-GS and MG2P 分子名称: CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... 著者 Fischmann, T.O. 登録日 2008-09-30 公開日 2009-02-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors. Biochemistry, 48, 2009
3NY0	Crystal Structure of UreE from Helicobacter pylori (Ni2+ bound form) 分子名称: NICKEL (II) ION, Urease accessory protein ureE 著者 Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-07-14 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites Biochemistry, 49, 2010
3EJQ	Golgi alpha-Mannosidase II in complex with 5-substitued swainsonine analog: (5R)-5-[2'-oxo-2'-(4-methylphenyl)ethyl]-swainsonine 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1-(4-methylphenyl)-2-[(1S,2R,5R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizin-5-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Rose, D.R. 登録日 2008-09-18 公開日 2009-10-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II. Chembiochem, 11, 2010
4HIM	Crystal Structure of Schizosaccharomyces pombe Pot1pC bound to ssDNA (GGATACGGT) 分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*CP*GP*GP*T)-3'), Protection of telomeres protein 1 著者 Dickey, T.H, Wuttke, D.S. 登録日 2012-10-11 公開日 2012-12-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes. Structure, 21, 2013
3NWM	Crystal structure of a single chain construct composed of MHC class I H-2Kd, beta-2microglobulin and a peptide which is an autoantigen for type 1 diabetes 分子名称: Peptide/beta-2microglobulin/MHC class I H-2Kd chimeric protein 著者 Ramagopal, U.A, Samanta, D, Nathenson, S.G, Almo, S.C. 登録日 2010-07-09 公開日 2011-07-06 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc.Natl.Acad.Sci.USA, 108, 2011
4HJ3	Crystal Structure of Rhodobacter Sphaeroides LOV protein 分子名称: FLAVIN MONONUCLEOTIDE, LOV protein 著者 Crane, B.R, Conrad, K.S, Bilwes, A.M. 登録日 2012-10-12 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.643 Å) 主引用文献 Light-induced subunit dissociation by a light-oxygen-voltage domain photoreceptor from Rhodobacter sphaeroides. Biochemistry, 52, 2013
3EKW	Crystal structure of the inhibitor Atazanavir (ATV) in complex with a multi-drug resistance HIV-1 protease variant (L10I/G48V/I54V/V64I/V82A) Refer: FLAP+ in citation. 分子名称: (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, PHOSPHATE ION, ... 著者 Prabu-Jeyabalan, M, King, N.M, Bandaranayake, R.M. 登録日 2008-09-19 公開日 2009-09-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease. Acs Chem.Biol., 7, 2012
3ESW	Complex of yeast PNGase with GlcNAc2-IAc. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, UV excision repair protein RAD23, ... 著者 Zhao, G, Zhou, X, Lennarz, W.J, Schindelin, H. 登録日 2008-10-06 公開日 2008-11-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase. Glycobiology, 19, 2009
4HJW	Crystal structure of Metarhizium anisopliae IDCase in apo form 分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION 著者 Xu, S, Zhu, J, Ding, J. 登録日 2012-10-14 公開日 2013-09-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
3E2S	Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with L-proline 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, PROLINE, ... 著者 Tanner, J.J. 登録日 2008-08-06 公開日 2009-02-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate. Biochemistry, 48, 2009
3EMG	Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK) 分子名称: 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide, Tyrosine-protein kinase SYK 著者 Ter Haar, E. 登録日 2008-09-24 公開日 2008-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK). Bioorg.Med.Chem.Lett., 18, 2008
4MK7	Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 2 (3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one) 分子名称: 3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Harris, S.F, Wong, A. 登録日 2013-09-04 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
4HM6	Naphthalene 1,2-Dioxygenase bound to phenetole 分子名称: 1,2-ETHANEDIOL, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Ferraro, D.J, Ramaswamy, S. 登録日 2012-10-17 公開日 2013-10-30 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Naphthalene 1,2-Dioxygenase bound to phenetole To be Published
4HM8	Naphthalene 1,2-Dioxygenase bound to thioanisole 分子名称: (methylsulfanyl)benzene, 1,2-ETHANEDIOL, FE (III) ION, ... 著者 Ferraro, D.J, Ramaswamy, S. 登録日 2012-10-17 公開日 2013-10-30 最終更新日 2016-04-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Naphthalene 1,2-Dioxygenase bound to thioanisole To be Published
3O15	Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate 分子名称: 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, PYROPHOSPHATE 2-, ... 著者 McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. 登録日 2010-07-20 公開日 2011-07-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure and Kinetic Characterization of Bacillus subtilis Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate to be published
4HO4	Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate 分子名称: 1-O-phosphono-alpha-D-glucopyranose, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... 著者 Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. 登録日 2012-10-22 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate TO BE PUBLISHED
4HO9	Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP 分子名称: GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... 著者 Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. 登録日 2012-10-22 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP TO BE PUBLISHED
3E24	H. influenzae beta-carbonic anhydrase, variant W39F 分子名称: Carbonic anhydrase 2, PHOSPHATE ION, ZINC ION 著者 Rowlett, R.S, Lee, J. 登録日 2008-08-05 公開日 2009-06-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Allosteric site variants of Haemophilus influenzae beta-carbonic anhydrase. Biochemistry, 48, 2009

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