PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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4RKO	Crystal structure of thrombin mutant S195T bound with PPACK 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... 著者 Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. 登録日 2014-10-13 公開日 2015-03-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Why ser and not thr brokers catalysis in the trypsin fold. Biochemistry, 54, 2015
4JFE	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
6UIN	Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex 分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*NP*NP*NP*NP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*CP*CP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... 著者 Paul, D, Min, J.-H. 登録日 2019-10-01 公開日 2020-10-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.348 Å) 主引用文献 Tethering-facilitated DNA 'opening' and complementary roles of beta-hairpin motifs in the Rad4/XPC DNA damage sensor protein Nucleic Acids Res., 48, 2021
4S1V	Crystal structure of phosphoglycerate oxidoreductase from Vibrio Cholerae o395 分子名称: D-3-phosphoglycerate dehydrogenase-related protein 著者 Tarique, K.F, Rehman, S.A.A, Devi, S, Gourinath, S. 登録日 2015-01-15 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Phosphoglycerate Oxidoreductase from Vibrio Cholerae O395 To be Published
6U1Z	Crystal Structure of Ketosteroid Isomerase from Pseudomonas Putida (pKSI) at 280 K 分子名称: CHLORIDE ION, MAGNESIUM ION, Steroid Delta-isomerase 著者 Yabukarski, F, Herschlag, D. 登録日 2019-08-18 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5005 Å) 主引用文献 Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles. Proc.Natl.Acad.Sci.USA, 117, 2020
3BB3	Crystal structure of Toc33 from Arabidopsis thaliana in complex with GDP and Mg2+ 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, T7I23.11 protein 著者 Koenig, P, Sinning, I, Schleiff, E, Tews, I. 登録日 2007-11-09 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures. Structure, 16, 2008
3R68	Molecular Analysis of the PDZ3 domain of PDZK1 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Kocher, O, Birrane, G, Krieger, M. 登録日 2011-03-21 公開日 2011-05-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I. J.Biol.Chem., 286, 2011
4O5J	Crystal structure of SabA from Helicobacter pylori 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Uncharacterized protein 著者 Pang, S.S, Nguyen, S.T.S, Whisstock, J.C. 登録日 2013-12-19 公開日 2014-01-01 最終更新日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The three-dimensional structure of the extracellular adhesion domain of the sialic acid-binding adhesin SabA from Helicobacter pylori J.Biol.Chem., 289, 2013
4H12	The crystal structure of methyltransferase domain of human SET domain-containing protein 2 in complex with S-adenosyl-L-homocysteine 分子名称: CHLORIDE ION, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Amaya, M.F, Dong, A, Zeng, H, Mackenzie, F, Bunnage, M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2012-09-10 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2. J.Am.Chem.Soc., 134, 2012
6UCH	SMARCB1 nucleosome-interacting C-terminal alpha helix 分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 著者 Valencia, A.M, Sun, Z.Y.J, Seo, H.S, Vangos, H.S, Yeoh, Z.C, Mashtalir, N, Dhe-Paganon, S, Kadoch, C. 登録日 2019-09-16 公開日 2019-11-27 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell, 179, 2019
6UF6	Crystal structure of B. subtilis TagU 分子名称: GLYCEROL, Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU, SULFATE ION 著者 Li, F.K.K, Strynadka, N.C.J. 登録日 2019-09-23 公開日 2020-01-29 最終更新日 2020-03-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase. J.Biol.Chem., 295, 2020
4HDT	Crystal structure of a Carnitinyl-CoA dehydratase from Mycobacterium thermoresistibile 分子名称: 3-hydroxyisobutyryl-CoA hydrolase, ACETATE ION, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-10-02 公開日 2012-10-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
6SGH	Nek2 kinase covalently bound to 2-arylamino-6-ethynylpurine inhibitor 66 分子名称: 2-[4-[(6-ethenyl-9~{H}-purin-2-yl)amino]phenyl]ethanamide, Serine/threonine-protein kinase Nek2 著者 Richards, M.W, Mas-Droux, C.P, Bayliss, R. 登録日 2019-08-04 公開日 2020-06-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase. Rsc Med Chem, 11, 2020
6SNY	Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ... 著者 Barber, N.M, Higgins, M.K. 登録日 2019-08-27 公開日 2019-09-04 最終更新日 2021-01-20 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein. Msphere, 6, 2021
4K8V	Structure of cyclic GMP-AMP Synthase (cGAS) 分子名称: Cyclic GMP-AMP synthase, ZINC ION 著者 Gao, P, Wu, Y, Patel, D.J. 登録日 2013-04-18 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
4JZF	Structure of factor VIIA in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid 分子名称: 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Wei, A, Anumula, R. 登録日 2013-04-02 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold. Bioorg.Med.Chem.Lett., 23, 2013
6HRD	Crystal structure of M. tuberculosis FadB2 (Rv0468) 分子名称: 3-hydroxybutyryl-CoA dehydrogenase, GLYCEROL 著者 Cox, J.A.G, Besra, G.S, Futterer, K. 登録日 2018-09-26 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial beta-oxidation. Acta Crystallogr D Struct Biol, 75, 2019
4JZE	Structure of factor VIIA in complex with the inhibitor 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid 分子名称: 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Wei, A, Anumula, R. 登録日 2013-04-02 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold. Bioorg.Med.Chem.Lett., 23, 2013
4JZD	Structure of factor VIIA in complex with the inhibitor 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid 分子名称: 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Factor VIIa (Heavy Chain), ... 著者 Jacobson, B.L, Anumula, R. 登録日 2013-04-02 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold. Bioorg.Med.Chem.Lett., 23, 2013
6RRK	Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide 分子名称: Cohesin subunit SA-1, Double-strand-break repair protein rad21 homolog 著者 Newman, J.A, katis, V.L, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-20 公開日 2019-06-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers. Life Sci Alliance, 3, 2020
6RXD	Crystal Structure of Bifidobacterium longum Multiple Inositol Polyphosphate Phosphatase Apo Form 分子名称: Histidine acid phosphatase, ZINC ION 著者 Li, A.W.H, Brearley, C.A, Hemmings, A.M. 登録日 2019-06-07 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism. J.Biol.Chem., 295, 2020
4TUM	Crystal structure of Ankyrin Repeat Domain of AKR2 分子名称: Ankyrin repeat domain-containing protein 2 著者 Gwon, G.H, Cho, Y. 登録日 2014-06-24 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 An Ankyrin Repeat Domain of AKR2 Drives Chloroplast Targeting through Coincident Binding of Two Chloroplast Lipids. Dev.Cell, 30, 2014
6RXE	Crystal Structure of Bifidobacterium longum Multiple Inositol Polyphosphate Phosphatase Complex with Inositol Hexasulfate 分子名称: D-MYO-INOSITOL-HEXASULPHATE, Histidine acid phosphatase, PHOSPHATE ION 著者 Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. 登録日 2019-06-07 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism. J.Biol.Chem., 295, 2020
6I0O	Structure of human IMP dehydrogenase, isoform 2, bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase 2, SULFATE ION 著者 Buey, R.M, Fernandez-Justel, D, Revuelta, J.L. 登録日 2018-10-26 公開日 2019-01-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 A Nucleotide-Dependent Conformational Switch Controls the Polymerization of Human IMP Dehydrogenases to Modulate their Catalytic Activity. J. Mol. Biol., 431, 2019
4KK3	YwlE arginine phosphatase - wildtype 分子名称: Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION 著者 Fuhrmann, J, Clausen, T. 登録日 2013-05-05 公開日 2013-07-03 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep, 3, 2013

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