6UIN
Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex
Summary for 6UIN
Entry DOI | 10.2210/pdb6uin/pdb |
Descriptor | DNA repair protein RAD4, UV excision repair protein RAD23, DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*CP*CP*CP*TP*AP*CP*AP*A)-3'), ... (4 entities in total) |
Functional Keywords | dna damage recognition, dna damage repair, nucleotide excision repair, beta-hairpin motif, xeroderma pigmentosum, xpc, rad4, molecular dynamics simulations, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 4 |
Total formula weight | 94610.99 |
Authors | Paul, D.,Min, J.-H. (deposition date: 2019-10-01, release date: 2020-10-14, Last modification date: 2023-10-11) |
Primary citation | Paul, D.,Mu, H.,Tavakoli, A.,Dai, Q.,Chen, X.,Chakraborty, S.,He, C.,Ansari, A.,Broyde, S.,Min, J.H. Tethering-facilitated DNA 'opening' and complementary roles of beta-hairpin motifs in the Rad4/XPC DNA damage sensor protein Nucleic Acids Res., 48:12348-12364, 2021 Cited by DOI: 10.1093/nar/gkaa909PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.348 Å) |
Structure validation
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