PDB: 41454 件ウェブページステータス検索Chemie searchBIRD

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6V03	ELIC-propylammonium complex in POPC-only nanodiscs 分子名称: 3-AMINOPROPANE, Gamma-aminobutyric-acid receptor subunit beta-1 著者 Grosman, C, Kumar, P. 登録日 2019-11-18 公開日 2020-01-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc.Natl.Acad.Sci.USA, 117, 2020
6UW8	Cryo-EM structure of the human TRPV3 K169A mutant briefly exposed to 2-APB for 3 minutes, determined in lipid nanodisc 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Deng, Z, Yuan, P. 登録日 2019-11-04 公開日 2020-07-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
3DS0	HIV-1 capsid C-terminal domain mutant (N183A) in complex with an inhibitor of particle assembly (CAI) 分子名称: HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly 著者 Igonet, S, Vaney, M.C, Rey, F.A. 登録日 2008-07-11 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
6V0B	Unliganded ELIC in POPC-only nanodiscs. 分子名称: Gamma-aminobutyric-acid receptor subunit beta-1 著者 Grosman, C, Kumar, P. 登録日 2019-11-18 公開日 2020-01-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc.Natl.Acad.Sci.USA, 117, 2020
6HQC	Structural investigation of the TasA anchoring protein TapA from Bacillus subtilis 分子名称: 1,2-ETHANEDIOL, TasA anchoring/assembly protein 著者 Roske, Y, Heinemann, U. 登録日 2018-09-24 公開日 2019-10-09 最終更新日 2023-04-26 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 TapA acts as specific chaperone in TasA filament formation by strand complementation. Proc.Natl.Acad.Sci.USA, 120, 2023
7N29	Structure of NAD kinase 分子名称: NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. 登録日 2021-05-28 公開日 2022-05-04 最終更新日 2022-06-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc.Natl.Acad.Sci.USA, 119, 2022
3S86	Crystal Structure of TM0159 with bound IMP 分子名称: INOSINIC ACID, Nucleoside-triphosphatase, SULFATE ION 著者 Sommerhalter, M, Smith, C, Awwad, K, Desai, A. 登録日 2011-05-27 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima. Acta Crystallogr.,Sect.D, 69, 2013
7N9H	Structure of the mammalian importin a1 bound to the TDP-43 NLS 分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43 著者 Doll, S.G, Lokareddy, R.K, Cingolani, G. 登録日 2021-06-17 公開日 2022-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta. Cell Rep, 39, 2022
1BW9	PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE 分子名称: 1,2-ETHANEDIOL, 3-PHENYLPYRUVIC ACID, ISOPROPYL ALCOHOL, ... 著者 Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. 登録日 1998-10-01 公開日 1999-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism. Biochemistry, 38, 1999
6V7P	Crystal structure of SUMO1 in complex with PIAS-SIM2 分子名称: Protein PIAS, Small ubiquitin-related modifier 1 著者 Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Sakaguchi, K, Omichinski, J.G. 登録日 2019-12-09 公開日 2020-04-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.395 Å) 主引用文献 Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins. Structure, 28, 2020
7ODC	CRYSTAL STRUCTURE ORNITHINE DECARBOXYLASE FROM MOUSE, TRUNCATED 37 RESIDUES FROM THE C-TERMINUS, TO 1.6 ANGSTROM RESOLUTION 分子名称: PROTEIN (ORNITHINE DECARBOXYLASE), PYRIDOXAL-5'-PHOSPHATE 著者 Kern, A.D, Oliveira, M.A, Coffino, P, Hackert, M.L. 登録日 1999-03-03 公開日 1999-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases. Structure Fold.Des., 7, 1999
6VJA	Structure of CD20 in complex with rituximab Fab 分子名称: B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, Rituximab Fab heavy chain, ... 著者 Rohou, A, Croll, T.I. 登録日 2020-01-15 公開日 2020-02-26 最終更新日 2020-03-25 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab. Science, 367, 2020
8R1C	SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-2 fab heavy chain, SD1-2 fab light chain, ... 著者 Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. 登録日 2023-11-01 公開日 2024-03-13 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
3D5E	Crystal structure of human plasma platelet activating factor acetylhydrolase covalently inhibited by paraoxon 分子名称: DIETHYL PHOSPHONATE, FORMIC ACID, Platelet-activating factor acetylhydrolase 著者 Samanta, U, Bahnson, B.J. 登録日 2008-05-16 公開日 2008-09-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase: STRUCTURAL IMPLICATION TO LIPOPROTEIN BINDING AND CATALYSIS. J.Biol.Chem., 283, 2008
1B3O	TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE 分子名称: 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ... 著者 Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M. 登録日 1998-12-14 公開日 1999-04-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96, 1999
7NUR	Structure of the Toxoplasma gondii kinase Ron13, kinase-dead mutant 分子名称: Protein kinase domain-containing protein 著者 Korkhov, V.M, Mehta, V. 登録日 2021-03-13 公開日 2021-05-26 最終更新日 2021-07-07 実験手法 ELECTRON MICROSCOPY (3.125 Å) 主引用文献 Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion. Nat Commun, 12, 2021
5GSQ	Crystal structure of IgG Fc with a homogeneous glycoform and Antibody-Dependent Cellular Cytotoxicity 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, C.-L, Hsu, J.-C, Lin, C.-W, Wu, C.-Y, Wong, C.-H, Ma, C. 登録日 2016-08-17 公開日 2017-06-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chem. Biol., 12, 2017
5G1S	Open conformation of Francisella tularensis ClpP at 1.7 A 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... 著者 Diaz-Saez, L, Pankov, G, Hunter, W.N. 登録日 2016-03-30 公開日 2016-10-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Open and compressed conformations of Francisella tularensis ClpP. Proteins, 85, 2017
3DTJ	HIV-1 capsid C-terminal domain mutant (E187A) 分子名称: HIV-1 capsid protein 著者 Igonet, S, Vaney, M.C, Rey, F.A. 登録日 2008-07-15 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
6VVU	Anti-Tryptase fab E104.v1 bound to tryptase 分子名称: CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ... 著者 Ultsch, M, Koerber, J.T. 登録日 2020-02-18 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge. Nat Commun, 11, 2020
1B4W	BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS-IMPLICATIONS FOR ITS ASSOCIATION AND ANTICOAGULANT ACTIVITIES BY X-RAY CRYSTALLOGRAPHY 分子名称: PROTEIN (PHOSPHOLIPASE A2), octyl beta-D-glucopyranoside 著者 Zhao, K.H, Lin, Z.J. 登録日 1998-12-30 公開日 2000-01-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of basic phospholipase A2 from Agkistrodon halys Pallas: implications for its association, hemolytic and anticoagulant activities. Toxicon, 38, 2000
1B70	PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE 分子名称: MAGNESIUM ION, PHENYLALANINE, PHENYLALANYL-TRNA SYNTHETASE 著者 Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. 登録日 1999-01-26 公開日 2000-02-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue J.Mol.Biol., 287, 1999
1K8C	Crystal structure of dimeric xylose reductase in complex with NADP(H) 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, xylose reductase 著者 Kavanagh, K.L, Klimacek, M, Nidetzky, B, Wilson, D.K. 登録日 2001-10-23 公開日 2002-07-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis. Biochemistry, 41, 2002
1C2O	ELECTROPHORUS ELECTRICUS ACETYLCHOLINESTERASE 分子名称: ACETYLCHOLINESTERASE 著者 Bourne, Y, Marchot, P. 登録日 1999-07-26 公開日 2000-01-19 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography. J.Biol.Chem., 274, 1999
6I4U	Crystal structure of the disease-causing G426E mutant of the human dihydrolipoamide dehydrogenase 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Szabo, E, Wilk, P, Hubert, A, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. 登録日 2018-11-10 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants. Hum.Mol.Genet., 28, 2019

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