PDB: 17097 件ウェブページステータス検索Chemie searchBIRD

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7U1E	CryoEM structure of the pancreatic ATP-sensitive potassium channel bound to ATP with Kir6.2-CTD in the down conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-21 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
6PFF	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-cyanobenzoic acid. 分子名称: 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-cyanobenzoic acid, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... 著者 Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.982 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
6W3R	Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with 3-methylisoleucine 分子名称: 3-methyl-L-alloisoleucine, CHLORIDE ION, Methyl-accepting chemotaxis protein, ... 著者 Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A. 登録日 2020-03-09 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3. Biomolecules, 10, 2020
7TYT	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with Kir6.2-CTD in the down conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-14 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
8GHU	Methyltransferase RmtC bound to the 30S ribosomal subunit 分子名称: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ... 著者 Srinivas, P, Conn, G.L, Dunham, C.M. 登録日 2023-03-12 公開日 2023-04-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Biorxiv, 2023
7TZA	Structure of PQS Response Protein PqsE in complex with N-(4-(3-neopentylureido)phenyl)-1H-indazole-7-carboxamide 分子名称: 1,2-ETHANEDIOL, FE (III) ION, N-{4-[(2,2-dimethylpropyl)carbamamido]phenyl}-1H-indazole-7-carboxamide, ... 著者 Jeffrey, P.D, Taylor, I.R, Bassler, B.L. 登録日 2022-02-15 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa. Biochemistry, 61, 2022
7U1Q	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-21 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U1S	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-out conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-22 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U24	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-23 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U6G	Structure of PQS Response Protein PqsE(E182W,E280A) Variant 分子名称: FE (III) ION, Quinolone signal response protein 著者 Jeffrey, P.D, Taylor, I.R, Bassler, B.L. 登録日 2022-03-04 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa. Biochemistry, 61, 2022
7U6Y	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of glibenclamide and ATP with Kir6.2-CTD in the down conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-03-06 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7U7M	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the up conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-03-07 公開日 2022-08-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
7TX7	Cryo-EM structure of the human reduced folate carrier 分子名称: Digitonin, Reduced folate transporter,Soluble cytochrome b562 著者 Wright, N.J, Fedor, J.G, Lee, S.-Y. 登録日 2022-02-07 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609, 2022
7U2X	Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Shyng, S.L, Sung, M.W, Driggers, C.M. 登録日 2022-02-25 公開日 2022-08-31 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel. J.Mol.Biol., 434, 2022
6Z8L	Alpha-Amylase in complex with probe fragments 分子名称: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ... 著者 Adam, S, Koehnke, J. 登録日 2020-06-02 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.40000367 Å) 主引用文献 Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design. Chem Sci, 12, 2020
7TX6	Cryo-EM structure of the human reduced folate carrier in complex with methotrexate 分子名称: Digitonin, METHOTREXATE, Reduced folate transporter,Soluble cytochrome b562 著者 Wright, N.J, Fedor, J.G, Lee, S.-Y. 登録日 2022-02-07 公開日 2022-09-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Methotrexate recognition by the human reduced folate carrier SLC19A1. Nature, 609, 2022
6W0M	Human 8-oxoguanine glycosylase crosslinked with oxoG lesion containing DNA 分子名称: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), ... 著者 Shigdel, U, Verdine, G. 登録日 2020-03-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
6W0R	Human 8-oxoguanine glycosylase interrogating fully intrahelical undamaged DNA 分子名称: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*AP*GP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*TP*GP*G)-3'), ... 著者 Shigdel, U, Verdine, G. 登録日 2020-03-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
6HGJ	Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with aldosterone 分子名称: 1,2-ETHANEDIOL, ALDOSTERONE, Alpha-1-antichymotrypsin 著者 Schmidt, K, Muller, Y.A. 登録日 2018-08-23 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.825 Å) 主引用文献 NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
7TIT	Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C 分子名称: Myosin-binding protein C, cardiac-type, cardiac actin, ... 著者 Risi, C.M, Galkin, V.E. 登録日 2022-01-14 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022
6ZJ9	Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione 分子名称: 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase 著者 Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P. 登録日 2020-06-28 公開日 2020-11-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants. Environ Pollut, 268, 2021
6WAV	Crystal structure of PHF1 in complex with H3K36me3 substitution 分子名称: Histone H3.1, PHD finger protein 1, SULFATE ION, ... 著者 Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) 登録日 2020-03-26 公開日 2020-08-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
7TJ7	Cardiac thin filament decorated with C1 Ig-domain and regulatory M-domain of cardiac myosin binding protein C (cMyBP-C) 分子名称: Myosin-binding protein C, cardiac-type, cardiac actin, ... 著者 Risi, C.M, Galkin, V.E. 登録日 2022-01-14 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022
7TIJ	Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C 分子名称: Myosin-binding protein C, cardiac-type, cardiac actin 著者 Risi, C.M, Galkin, V.E. 登録日 2022-01-13 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament. J.Mol.Biol., 434, 2022
6W3X	Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with L-valine 分子名称: GLYCEROL, Methyl-accepting chemotaxis protein, SULFATE ION, ... 著者 Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A. 登録日 2020-03-09 公開日 2020-05-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3. Biomolecules, 10, 2020

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