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7U24

Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and glibenclamide with Kir6.2-CTD in the up conformation

Summary for 7U24
Entry DOI10.2210/pdb7u24/pdb
Related6PZA 7TYS 7TYT 7U1Q 7U1S
EMDB information20530 26307
DescriptorATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE, ... (8 entities in total)
Functional Keywordskatp channel, sur1, kir6.2, glibenclamide, gbc, gbm, sulfonylurea receptor, potassium transport, metabolic sensor, membrane protein
Biological sourceRattus norvegicus (Norway rat)
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Total number of polymer chains5
Total formula weight369070.92
Authors
Shyng, S.L.,Sung, M.W.,Driggers, C.M. (deposition date: 2022-02-23, release date: 2022-08-31, Last modification date: 2022-09-14)
Primary citationSung, M.W.,Driggers, C.M.,Mostofian, B.,Russo, J.D.,Patton, B.L.,Zuckerman, D.M.,Shyng, S.L.
Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434:167789-167789, 2022
Cited by
PubMed: 35964676
DOI: 10.1016/j.jmb.2022.167789
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.58 Å)
Structure validation

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