8GMH
 
 | | Crystal Structure of the ternary complex of TelA-LXG, LapA3, and LapA4 | | 分子名称: | 1,2-ETHANEDIOL, LXG domain-containing protein, LapA3, ... | | 著者 | Klein, T.A, Shah, P.Y, Gkragkopoulou, P, Grebenc, D.W, Kim, Y, Whitney, J.C. | | 登録日 | 2023-03-25 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of a tripartite protein complex that targets toxins to the type VII secretion system.
Proc.Natl.Acad.Sci.USA, 121, 2024
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5MF5
 | | PA3825-EAL Mg-CdG Structure | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate phosphodiesterase, MAGNESIUM ION | | 著者 | Horrell, S, Bellini, D, Strange, R, Wagner, A, Walsh, M. | | 登録日 | 2016-11-17 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases.
Sci Rep, 7, 2017
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4QBZ
 | | Crystal structure of human TLR8 in complex with DS-802 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine, ... | | 著者 | Tanji, H, Ohto, U, Shimizu, T. | | 登録日 | 2014-05-09 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Determinants of Activity at Human Toll-like Receptors 7 and 8: Quantitative Structure-Activity Relationship (QSAR) of Diverse Heterocyclic Scaffolds
J.Med.Chem., 57, 2014
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2VJJ
 | | TAILSPIKE PROTEIN OF E.COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Mueller, J.J, Barbirz, S, Uetrecht, C, Seckler, R, Heinemann, U. | | 登録日 | 2007-12-11 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Crystal Structure of Escherichia Coli Phage Hk620 Tailspike: Podoviral Tailspike Endoglycosidase Modules are Evolutionarily Related.
Mol.Microbiol., 69, 2008
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7R3R
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7R3Q
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4YTB
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln. | | 分子名称: | ASPARTIC ACID, AZIDE ION, CHLORIDE ION, ... | | 著者 | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2015-03-17 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
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4R3S
 | | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23 | | 分子名称: | FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein | | 著者 | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | | 登録日 | 2014-08-18 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
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7QQC
 | | Structure of CTX-M-15 K73A mutant | | 分子名称: | Beta-lactamase, CHLORIDE ION, SULFATE ION | | 著者 | Tooke, C.L, Hinchliffe, P, Spencer, J. | | 登録日 | 2022-01-07 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Penicillanic Acid Sulfones Inactivate the Extended-Spectrum beta-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of beta-Lactamase Inhibition.
Mbio, 13, 2022
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7QQ5
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4YM2
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2WJH
 | | Structure and function of the FeoB G-domain from Methanococcus jannaschii | | 分子名称: | CITRATE ANION, FERROUS IRON TRANSPORT PROTEIN B HOMOLOG, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Koester, S, Wehner, M, Herrmann, C, Kuehlbrandt, W, Yildiz, O. | | 登録日 | 2009-05-26 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and Function of the Feob G-Domain from Methanococcus Jannaschii
J.Mol.Biol., 392, 2009
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2WIY
 | | Cytochrome P450 XplA heme domain P21212 | | 分子名称: | 1,2-ETHANEDIOL, CYTOCHROME P450-LIKE PROTEIN XPLA, IMIDAZOLE, ... | | 著者 | Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. | | 登録日 | 2009-05-18 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive.
J.Biol.Chem., 284, 2009
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8EYY
 | | Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S, denoted as IR-3CS) Asymmetric conformation 2 | | 分子名称: | Insulin, Insulin receptor | | 著者 | Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E. | | 登録日 | 2022-10-29 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
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7LD5
 | | polynucleotide phosphorylase | | 分子名称: | MAGNESIUM ION, Polyribonucleotide nucleotidyltransferase, poly-A RNA fragment | | 著者 | Goldgur, Y, Shuman, S, De La Cruz, M.J, Ghosh, S, Unciuleac, M.-C. | | 登録日 | 2021-01-12 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase.
Rna, 27, 2021
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5VKD
 | | Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | | 分子名称: | Fab Heavy Chain, Fab light chain, Nucleoprotein | | 著者 | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | | 登録日 | 2017-04-21 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
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8F2G
 | | Crystal structure of Hen Egg White Lysozyme at 0.44 GPa | | 分子名称: | Lysozyme C | | 著者 | Marshall, A.C, Boer, S.A, Turner, G, Moggach, S.A, Bond, C.S, Vrielink, A. | | 登録日 | 2022-11-08 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | High-pressure single-crystal diffraction at the Australian Synchrotron.
J.Synchrotron Radiat., 30, 2023
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6H79
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6T5B
 | | KRasG12C ligand complex | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Phillips, C. | | 登録日 | 2019-10-15 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C.
J.Med.Chem., 63, 2020
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2WIV
 | | Cytochrome-P450 XplA heme domain P21 | | 分子名称: | CYTOCHROME P450-LIKE PROTEIN XPLA, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. | | 登録日 | 2009-05-18 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive.
J.Biol.Chem., 284, 2009
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6VWI
 | | Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | | 著者 | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | | 登録日 | 2020-02-19 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
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6NKZ
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2UXY
 | | Aliphatic amidase | | 分子名称: | ALIPHATIC AMIDASE, SULFATE ION | | 著者 | Andrade, J, KArmali, A, Carrondo, M.A, Frazao, C. | | 登録日 | 2007-04-02 | | 公開日 | 2007-04-17 | | 最終更新日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structure of Amidase from Pseudomonas Aeruginosa Showing a Trapped Acyl Transfer Reaction Intermediate State.
J.Biol.Chem., 282, 2007
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4OMK
 | | Crystal structure of SPF bound to squalene | | 分子名称: | (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | | 著者 | Christen, M, Marcaida, M.J, Lamprakis, C, Cascella, M, Stocker, A. | | 登録日 | 2014-01-27 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
J.Struct.Biol., 190, 2015
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6UCX
 | | S2 symmetric peptide design number 1, Wednesday | | 分子名称: | S2-1, Wednesday, trifluoroacetic acid | | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | | 登録日 | 2019-09-18 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry.
Protein Sci., 29, 2020
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