PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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2MMC	Nucleotide-free human ran gtpase 分子名称: GTP-binding nuclear protein Ran 著者 Bacot-Davis, V.R, Palmenberg, A.C. 登録日 2014-03-13 公開日 2014-10-22 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Structure of Ran GTPase Determines C-terminal Tail Conformational Dynamics. To be Published
3MXY	Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their Functional Implications. 分子名称: AICD peptide E683V variant, Growth factor receptor-bound protein 2 著者 Sen, U, Das, S. 登録日 2010-05-08 公開日 2011-05-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain. J.Mol.Biol., 414, 2011
3MXD	Crystal structure of HIV-1 protease inhibitor KC53 in complex with wild-type protease 分子名称: (5S)-N-{(1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(2-methylpropyl)amino]-1-benzyl-2-hydroxypropyl}-3-(2-hydroxyphenyl)-2 -oxo-1,3-oxazolidine-5-carboxamide, ACETATE ION, HIV-1 protease, ... 著者 Nalam, M.N.L, Schiffer, C.A. 登録日 2010-05-07 公開日 2010-11-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design, Synthesis, and Structure-Activity Relationship Studies of HIV-1 Protease Inhibitors Incorporating Phenyloxazolidinones. J.Med.Chem., 53, 2010
3MVC	High resolution crystal structure of the heme domain of GLB-6 from C. elegans 分子名称: Globin protein 6, NITRATE ION, PRASEODYMIUM ION, ... 著者 Yoon, J, Herzik Jr, M.A, Winter, M.B, Tran, R, Olea Jr, C, Marletta, M.A. 登録日 2010-05-03 公開日 2010-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Biochemistry, 49, 2010
3MVM	P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V 分子名称: 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 著者 Sack, J.S. 登録日 2010-05-04 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38? Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
2M96	Solution NMR structure of the RXFP2 LDLa module 分子名称: CALCIUM ION, Relaxin receptor 2 著者 Petrie, E.J, Gooley, P.R, Bathgate, A.D. 登録日 2013-06-03 公開日 2014-06-04 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of the RXFP2 LDLa module To be Published
3MVL	P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K 分子名称: 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 著者 Sack, J.S. 登録日 2010-05-04 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38 Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
3MW1	p38 kinase Crystal structure in complex with small molecule inhibitor 分子名称: 8-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)-2-piperidin-4-yl-1,7-naphthyridine 7-oxide, Mitogen-activated protein kinase 14 著者 Segarra, V, Caturla, F, Lumeras, W, Roca, R, Fisher, M, Lamers, M. 登録日 2010-05-05 公開日 2011-04-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 1,7-Naphthyridine 1-Oxides as Novel Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase J.Med.Chem., 54, 2011
3MVR	Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2010-05-04 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography. J.Biol.Chem., 285, 2010
2MNG	Apo Structure of human HCN4 CNBD solved by NMR 分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Akimoto, M, Zhang, Z, Boulton, S, Selvaratnam, R, VanSchouwen, B, Gloyd, M, Accili, E.A, Lange, O.F, Melacini, G. 登録日 2014-04-03 公開日 2014-06-04 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J.Biol.Chem., 289, 2014
3MWZ	Crystal structure of the selenomethionine derivative of the L 22,47,100 M mutant of sialostatin L2 分子名称: SULFATE ION, sialostatin L2 著者 Andersen, J.F. 登録日 2010-05-06 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Mol.Microbiol., 77, 2010
3MWS	Crystal Structure of Group N HIV-1 Protease 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease 著者 Sayer, J.M, Agniswamy, J, Weber, I.T, Louis, J.M. 登録日 2010-05-06 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Autocatalytic maturation, physical/chemical properties, and crystal structure of group N HIV-1 protease: relevance to drug resistance. Protein Sci., 19, 2010
3MX8	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: CHLORIDE ION, Ribonuclease pancreatic, LINKER, ... 著者 Leich, F, Neumann, P, Lilie, H, Ulbrich-Hofmann, R, Arnold, U. 登録日 2010-05-07 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011
2LYZ	Real-space refinement of the structure of hen egg-white lysozyme 分子名称: HEN EGG WHITE LYSOZYME 著者 Diamond, R, Phillips, D.C, Blake, C.C.F, North, A.C.T. 登録日 1975-02-01 公開日 1977-04-12 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Real-space refinement of the structure of hen egg-white lysozyme. J.Mol.Biol., 82, 1974
3MXH	Native structure of a c-di-GMP riboswitch from V. cholerae 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... 著者 Strobel, S.A, Smith, K.D. 登録日 2010-05-07 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010
3MYG	Aurora A Kinase complexed with SCH 1473759 分子名称: 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL 著者 Hruza, A, Prosis, W, Ramanathan, L. 登録日 2010-05-10 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core. ACS Med Chem Lett, 1, 2010
3MYN	Mutation of Methionine-86 in Dehaloperoxidase-hemoglobin: Effects of the Asp-His-Fe Triad in a 3/3 Globin 分子名称: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Bowden, E.F, de Serrano, V.S, D'Antonio, E.L, Franzen, S. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin. Biochemistry, 50, 2011
3MTL	Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804 分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cell division protein kinase 16 著者 Krojer, T, Sharpe, T.D, Roos, A, Savitsky, P, Amos, A, Ayinampudi, V, Berridge, G, Fedorov, O, Keates, T, Phillips, C, Burgess-Brown, N, Zhang, Y, Pike, A.C.W, Muniz, J, Vollmar, M, Thangaratnarajah, C, Rellos, P, Ugochukwu, E, Filippakopoulos, P, Yue, W, Das, S, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-04-30 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochem.J., 474, 2017
2MY3	Snu17p-Pml1p structure intermediate during RES complex assembly 分子名称: Pre-mRNA leakage protein 1, U2 snRNP component IST3 著者 Wysoczanski, P, Becker, S, Zweckstetter, M. 登録日 2015-01-19 公開日 2015-08-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structures of intermediates during RES complex assembly. Sci Rep, 5, 2015
3MWQ	Crystal structure of ribonuclease A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor 分子名称: GLYCEROL, Ribonuclease pancreatic, LINKER, ... 著者 Neumann, P, Leich, F. 登録日 2010-05-06 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor Febs J., 278, 2011
3N3I	Crystal Structure of G48V/C95F tethered HIV-1 Protease/Saquinavir complex 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease 著者 Prashar, V, Bihani, S.C, Das, A, Rao, D.R, Hosur, M.V. 登録日 2010-05-20 公開日 2010-06-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Insights into the mechanism of drug resistance: X-ray structure analysis of G48V/C95F tethered HIV-1 protease dimer/saquinavir complex Biochem.Biophys.Res.Commun., 396, 2010
7C7J	Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(G12V,Q63E) 分子名称: CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Xiao, L.X, Pan, L.F. 登録日 2020-05-25 公開日 2021-05-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Mechanistic Insights into the Interactions of Ras Subfamily GTPases with the SPN Domain of Autism-associated SHANK3. Chin.J.Chem., 38, 2020
3MU5	Comparison of the character and the speed of X-ray-induced structural changes of porcine pancreatic elastase at two temperatures, 100 and 15K. The data set was collected from region B of the crystal. Third step of radiation damage 分子名称: Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION 著者 Petrova, T, Ginell, S, Mitschler, A, Cousido-Siah, A, Hazemann, I, Podjarny, A, Joachimiak, A. 登録日 2010-05-01 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.404 Å) 主引用文献 X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
2MP1	Solution structure of the human chemokine CCL19 分子名称: C-C motif chemokine 19 著者 Veldkamp, C.T, Peterson, F.C, Gabel-Eissens, S.J, Gillitzer, M.L. 登録日 2014-05-09 公開日 2015-06-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of CCL19 and Identification of Overlapping CCR7 and PSGL-1 Binding Sites. Biochemistry, 54, 2015
3MUT	Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), G20A/C92U mutant c-di-GMP riboswitch, MAGNESIUM ION, ... 著者 Strobel, S.A, Smith, K.D. 登録日 2010-05-03 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry, 49, 2010

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