3MUT

Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-GMP

Summary for 3MUT

• Entry DOI: 10.2210/pdb3mut/pdb
• Related: 3IRW 3MUM 3MUR 3MUV 3MXH
• Descriptor: U1 small nuclear ribonucleoprotein A, G20A/C92U mutant c-di-GMP riboswitch, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (5 entities in total)
• Functional Keywords: rna, riboswitch, c-di-gmp, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P09012
• Total number of polymer chains: 2
• Total formula weight: 42007.09

Authors

Strobel, S.A.,Smith, K.D. (deposition date: 2010-05-03, release date: 2010-08-25, Last modification date: 2023-09-06)

• Primary citation: Smith, K.D.,Lipchock, S.V.,Livingston, A.L.,Shanahan, C.A.,Strobel, S.A.; Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .; Biochemistry, 49:7351-7359, 2010; PubMed: 20690679; DOI: 10.1021/bi100671e

Experimental method

X-RAY DIFFRACTION (3 Å)