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8XKY
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Structure of the TOM40 complex annealed
分子名称: Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, ...
著者Yang, L.Y, Shen, Q.T.
登録日2023-12-25
公開日2024-12-25
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structure of the TOM40 complex annealed
To Be Published
5IEE
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BU of 5iee by Molmil
Murine endoplasmic reticulum alpha-glucosidase II with 1-deoxynojirimycin
分子名称: 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N.
登録日2016-02-25
公開日2016-07-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
5LY7
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BU of 5ly7 by Molmil
Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin
分子名称: 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, Beta-hexosaminidase, DI(HYDROXYETHYL)ETHER
著者Acebron, I, Artola-Recolons, C, Mahasenan, K, Mobashery, S, Hermoso, J.A.
登録日2016-09-25
公開日2017-05-17
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.
J. Am. Chem. Soc., 139, 2017
5NVR
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BU of 5nvr by Molmil
Crystal structure of the Rif1 N-terminal domain (RIF1-NTD) from Saccharomyces cerevisiae
分子名称: Telomere length regulator protein RIF1
著者Bunker, R.D, Shi, T, Thoma, N.H.
登録日2017-05-04
公開日2017-06-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Nat. Struct. Mol. Biol., 24, 2017
6R9I
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BU of 6r9i by Molmil
Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module
分子名称: PAN2-PAN3 deadenylation complex catalytic subunit PAN2
著者Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A.
登録日2019-04-03
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
5CYZ
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BU of 5cyz by Molmil
Structure of S. cerevisiae Hrr25:Mam1 complex, form 1
分子名称: Casein kinase I homolog HRR25, Monopolin complex subunit MAM1, ZINC ION
著者Ye, Q, Corbett, K.D.
登録日2015-07-31
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.841 Å)
主引用文献Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.
Embo J., 35, 2016
5EL6
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BU of 5el6 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G.
登録日2015-11-04
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
8A2C
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BU of 8a2c by Molmil
The crystal structure of the S178A mutant of PET40, a PETase enzyme from an unclassified Amycolatopsis
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Costanzi, E, Applegate, V, Port, A, Smits, S.H.J.
登録日2022-06-03
公開日2023-06-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).
Febs J., 291, 2024
5IWU
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Macrolide 2'-phosphotransferase type II complexed with erythromycin
分子名称: ACETATE ION, CALCIUM ION, ERYTHROMYCIN A, ...
著者Berghuis, A.M, Fong, D.H.
登録日2016-03-22
公開日2017-04-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Structure, 25, 2017
8ZPW
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BU of 8zpw by Molmil
Cryo-EM structure of the yeast Htm1/Pdi1 complex at a resolution of 3.0 angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ER degradation-enhancing alpha-mannosidase-like protein 1, ...
著者Wu, X.W, Zhao, D, Rapoport, T.A.
登録日2024-05-31
公開日2024-11-13
最終更新日2024-11-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Initiation of ERAD by the bifunctional complex of Mnl1 mannosidase and protein disulfide isomerase.
Biorxiv, 2024
5CZO
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BU of 5czo by Molmil
Structure of S. cerevisiae Hrr25:Mam1 complex, form 2
分子名称: Casein kinase I homolog HRR25, Monopolin complex subunit MAM1, ZINC ION
著者Ye, Q, Corbett, K.D.
登録日2015-07-31
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Structure of the Saccharomyces cerevisiae Hrr25:Mam1 monopolin subcomplex reveals a novel kinase regulator.
Embo J., 35, 2016
1DS3
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BU of 1ds3 by Molmil
CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I
分子名称: OVOMUCOID
著者Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2000-01-06
公開日2001-01-31
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
6CBO
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BU of 6cbo by Molmil
X-ray structure of GenB1 from micromonospora echinospora in complex with neamine and PLP (as the external aldimine)
分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside, 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
著者Dow, G.T, Thoden, J.B, Holden, H.M.
登録日2018-02-03
公開日2018-02-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.
Protein Sci., 27, 2018
4URO
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BU of 4uro by Molmil
Crystal Structure of Staph GyraseB 24kDa in complex with Novobiocin
分子名称: DNA GYRASE SUBUNIT B, NOVOBIOCIN
著者Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B.
登録日2014-07-01
公開日2014-07-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
Acs Chem.Biol., 9, 2014
6CFD
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BU of 6cfd by Molmil
ADEP4 bound to E. faecium ClpP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, N-[(6aS,12S,15aS,17R,21R,23aS)-17,21-dimethyl-6,11,15,20,23-pentaoxooctadecahydro-2H,6H,11H,15H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13]oxatetraazacyclohexadecin-12-yl]-3,5-difluoro-Nalpha-[(2E)-hept-2-enoyl]-L-phenylalaninamide
著者Lee, R.E, Griffith, E.C.
登録日2018-02-14
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献In VivoandIn VitroEffects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.
Antimicrob. Agents Chemother., 62, 2018
5H29
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BU of 5h29 by Molmil
Crystal Structure of the NTD_N/C domain of Alkylhydroperoxide Reductase AhpF from Enterococcus Faecalis (V583)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PROLINE, SULFATE ION, ...
著者Balakrishna, A.M, Kwang, T.Y, Gruber, G.
登録日2016-10-14
公開日2017-11-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Novel insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F
Biochim. Biophys. Acta, 1861, 2017
4WUH
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BU of 4wuh by Molmil
Crystal structure of E. faecalis DNA binding domain LiaR wild type complexed with 22bp DNA
分子名称: DNA (5'-D(P*AP*AP*AP*TP*CP*G)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*TP*AP*AP*GP*AP*AP*CP*GP*AP*TP*TP*T)-3'), DNA (5'-D(P*TP*TP*CP*TP*TP*AP*AP*GP*TP*CP*C)-3'), ...
著者Davlieva, M, Shamoo, Y.
登録日2014-10-31
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Nucleic Acids Res., 43, 2015
7AQS
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BU of 7aqs by Molmil
Crystal structure of E. coli DPS in space group P1
分子名称: DNA protection during starvation protein, FE (III) ION
著者Jakob, R.P, Pipercevic, J, Righetto, R, Goldie, K, Stahlberg, H, Maier, T, Hiller, S.
登録日2020-10-22
公開日2021-09-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Identification of a Dps contamination in Mitomycin-C-induced expression of Colicin Ia.
Biochim Biophys Acta Biomembr, 1863, 2021
4WSZ
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BU of 4wsz by Molmil
Crystal structure of the DNA binding domains of wild type LiaR from E. faecalis
分子名称: ACETATE ION, GLYCEROL, PRASEODYMIUM ION, ...
著者Davlieva, M, Shamoo, Y.
登録日2014-10-29
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Nucleic Acids Res., 43, 2015
8QX8
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BU of 8qx8 by Molmil
Endosomal membrane tethering complex CORVET
分子名称: E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar protein sorting-associated protein 16, ...
著者Shvarev, D, Ungermann, C, Moeller, A.
登録日2023-10-23
公開日2024-07-03
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the endosomal CORVET tethering complex.
Nat Commun, 15, 2024
8QOF
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BU of 8qof by Molmil
Cryo-EM structure of the yeast SPT-Orm2-Dimer complex
分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ORM2 isoform 1, PYRIDOXAL-5'-PHOSPHATE, ...
著者Schaefer, J, Koerner, C, Moeller, A, Froehlich, F.
登録日2023-09-28
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins.
Cell Rep, 43, 2024
8QOG
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BU of 8qog by Molmil
Cryo-EM structure of the yeast SPT-Orm2-Monomer complex
分子名称: 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ORM2 isoform 1, PYRIDOXAL-5'-PHOSPHATE, ...
著者Schaefer, J, Koerner, C, Moeller, A, Froehlich, F.
登録日2023-09-28
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins.
Cell Rep, 43, 2024
7YHE
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BU of 7yhe by Molmil
Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG
分子名称: 2-OXOGLUTARIC ACID, CmnC, FE (III) ION, ...
著者Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y.
登録日2022-07-13
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
4WUL
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BU of 4wul by Molmil
Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 26bp DNA
分子名称: DNA (26-MER), Response regulator receiver domain protein
著者Davlieva, M, Shamoo, Y.
登録日2014-11-02
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Nucleic Acids Res., 43, 2015
8QTN
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Cryo-EM structure of the apo yeast Ceramide Synthase
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, AMMONIUM ION, Ceramide synthase LAC1, ...
著者Schaefer, J, Clausmeyer, L, Koerner, C, Moeller, A, Froehlich, F.
登録日2023-10-12
公開日2024-10-23
最終更新日2025-03-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the yeast ceramide synthase.
Nat.Struct.Mol.Biol., 32, 2025

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件を2025-05-14に公開中

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