7YHE
Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG
Summary for 7YHE
| Entry DOI | 10.2210/pdb7yhe/pdb |
| Descriptor | CmnC, 2-OXOGLUTARIC ACID, TRIETHYLENE GLYCOL, ... (5 entities in total) |
| Functional Keywords | hydroxylase, oxygenase, oxidoreductase |
| Biological source | Saccharothrix mutabilis subsp. capreolus |
| Total number of polymer chains | 2 |
| Total formula weight | 78739.34 |
| Authors | Huang, S.J.,Hsiao, Y.H.,Lin, E.C.,Hsiao, P.Y.,Chang, C.Y. (deposition date: 2022-07-13, release date: 2023-07-19, Last modification date: 2023-11-29) |
| Primary citation | Hsiao, Y.H.,Huang, S.J.,Lin, E.C.,Hsiao, P.Y.,Toh, S.I.,Chen, I.H.,Xu, Z.,Lin, Y.P.,Liu, H.J.,Chang, C.Y. Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer. Front Chem, 10:1001311-1001311, 2022 Cited by PubMed: 36176888DOI: 10.3389/fchem.2022.1001311 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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