5LY7

Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin

Summary for 5LY7

Entry DOI	10.2210/pdb5ly7/pdb
Descriptor	Beta-hexosaminidase, DI(HYDROXYETHYL)ETHER, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, ... (4 entities in total)
Functional Keywords	cell-wall recycling beta-hexosaminidase pseudomonas aeruginosa inhibitor, gene regulation
Biological source	Pseudomonas aeruginosa
Cellular location	Cytoplasm : Q9HZK0
Total number of polymer chains	2
Total formula weight	77121.90
Authors	Acebron, I.,Artola-Recolons, C.,Mahasenan, K.,Mobashery, S.,Hermoso, J.A. (deposition date: 2016-09-25, release date: 2017-05-17, Last modification date: 2017-05-31)
Primary citation	Acebron, I.,Mahasenan, K.V.,De Benedetti, S.,Lee, M.,Artola-Recolons, C.,Hesek, D.,Wang, H.,Hermoso, J.A.,Mobashery, S. Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa. J. Am. Chem. Soc., 139:6795-6798, 2017 Cited by PubMed: 28482153 DOI: 10.1021/jacs.7b01626 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation