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3NBN
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BU of 3nbn by Molmil
Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA
分子名称: DNA, HES1 promoter, Mastermind-like protein 1, ...
著者Arnett, K.L, Blacklow, S.C.
登録日2010-06-03
公開日2010-11-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.
Nat.Struct.Mol.Biol., 17, 2010
8QQI
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BU of 8qqi by Molmil
E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800
分子名称: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ...
著者Ghilarov, D, Martin, N.I, van der Stelt, M.
登録日2023-10-04
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.
Nat.Chem., 16, 2024
7PP4
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BU of 7pp4 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Brodolin, K.
登録日2021-09-13
公開日2022-09-21
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Nat Commun, 14, 2023
2OXV
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BU of 2oxv by Molmil
Structure of the A138T promiscuous mutant of the EcoRI restriction endonuclease bound to its cognate recognition site.
分子名称: DNA (5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), Type II restriction enzyme EcoRI
著者Sapienza, P.J, Rosenberg, J.M, Jen-Jacobson, L.
登録日2007-02-21
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and thermodynamic basis for enhanced DNA binding by a promiscuous mutant EcoRI endonuclease.
Structure, 15, 2007
6RQT
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BU of 6rqt by Molmil
RNA Polymerase I-tWH-Rrn3-DNA
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-16
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RFL
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BU of 6rfl by Molmil
Structure of the complete Vaccinia DNA-dependent RNA polymerase complex
分子名称: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ...
著者Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U.
登録日2019-04-15
公開日2019-12-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Cell, 179, 2019
7Q59
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BU of 7q59 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Brodolin, K.
登録日2021-11-03
公開日2022-11-16
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Nat Commun, 14, 2023
6WMU
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BU of 6wmu by Molmil
E. coli RNAPs70-SspA-gadA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
6RRD
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BU of 6rrd by Molmil
RNA Polymerase I Pre-initiation complex DNA opening intermediate 1
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-17
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
6RUI
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BU of 6rui by Molmil
RNA Polymerase I Pre-initiation complex DNA opening intermediate 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Mueller, C.W, Sadian, Y, Tafur, L.
登録日2019-05-28
公開日2019-12-11
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
1TRR
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BU of 1trr by Molmil
TANDEM BINDING IN CRYSTALS OF A TRP REPRESSOR/OPERATOR HALF-SITE COMPLEX
分子名称: DNA (5'-D(*AP*GP*CP*GP*TP*AP*CP*TP*AP*GP*TP*AP*CP*GP*CP*T)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
著者Lawson, C.L, Carey, J.
登録日1993-10-21
公開日1993-10-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Tandem binding in crystals of a trp repressor/operator half-site complex.
Nature, 366, 1993
7RSS
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BU of 7rss by Molmil
Kod-RI incorporating DNA, n+2
分子名称: DNA polymerase, Primer, Template
著者Hajjar, M, Chim, N, Chaput, J.C.
登録日2021-08-11
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid.
Nucleic Acids Res., 50, 2022
8F1J
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BU of 8f1j by Molmil
SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A)
分子名称: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Mueller, A.U, Chen, J, Darst, S.A.
登録日2022-11-05
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F1K
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BU of 8f1k by Molmil
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T)
分子名称: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Mueller, A.U, Chen, J, Darst, S.A.
登録日2022-11-05
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
6GYM
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BU of 6gym by Molmil
Structure of a yeast closed complex with distorted DNA (CCdist)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P.
登録日2018-06-30
公開日2018-12-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Mol. Cell, 73, 2019
4CS5
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BU of 4cs5 by Molmil
Crystal Structure of PCNA from Litopenaeus vannamei
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN
著者Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
登録日2014-03-04
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
6WMR
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BU of 6wmr by Molmil
F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
4WLW
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BU of 4wlw by Molmil
CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA
分子名称: DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ...
著者Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V.
登録日2014-10-08
公開日2015-09-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
Science, 349, 2015
1CZ0
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BU of 1cz0 by Molmil
INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION
分子名称: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SODIUM ION, ...
著者Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L.
登録日1999-08-31
公開日1999-11-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A novel endonuclease mechanism directly visualized for I-PpoI.
Nat.Struct.Biol., 6, 1999
6GYL
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BU of 6gyl by Molmil
Structure of a yeast closed complex with distorted DNA (core CCdist)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P.
登録日2018-06-30
公開日2018-12-05
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Mol. Cell, 73, 2019
7T02
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BU of 7t02 by Molmil
Cryo-EM structure of DNMT5 pseudo-ternary complex solved by incubation with hemimethylated DNA and SAM
分子名称: DNA (5'-D(*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*G)-3'), DNA repair protein Rad8, ...
著者Wang, J, Patel, D.J.
登録日2021-11-29
公開日2022-02-23
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance.
Mol.Cell, 82, 2022
7NVT
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BU of 7nvt by Molmil
RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Aibara, S, Schilbach, S, Cramer, P.
登録日2021-03-16
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVU
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BU of 7nvu by Molmil
RNA polymerase II core pre-initiation complex with open promoter DNA
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Aibara, S, Schilbach, S, Cramer, P.
登録日2021-03-16
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7NVS
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BU of 7nvs by Molmil
RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Aibara, S, Schilbach, S, Cramer, P.
登録日2021-03-16
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
5XFR
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BU of 5xfr by Molmil
Ternary complex of MTF2, DNA and histone
分子名称: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ...
著者Wang, Z, Li, H.
登録日2017-04-11
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017

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