3NBN
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8QQI
| E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800 | 分子名称: | DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ... | 著者 | Ghilarov, D, Martin, N.I, van der Stelt, M. | 登録日 | 2023-10-04 | 公開日 | 2024-06-19 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat.Chem., 16, 2024
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7PP4
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2OXV
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6RQT
| RNA Polymerase I-tWH-Rrn3-DNA | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Mueller, C.W, Sadian, Y, Tafur, L. | 登録日 | 2019-05-16 | 公開日 | 2019-12-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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6RFL
| Structure of the complete Vaccinia DNA-dependent RNA polymerase complex | 分子名称: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | 著者 | Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U. | 登録日 | 2019-04-15 | 公開日 | 2019-12-11 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes. Cell, 179, 2019
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7Q59
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6WMU
| E. coli RNAPs70-SspA-gadA DNA complex | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | 登録日 | 2020-04-21 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
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6RRD
| RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Mueller, C.W, Sadian, Y, Tafur, L. | 登録日 | 2019-05-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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6RUI
| RNA Polymerase I Pre-initiation complex DNA opening intermediate 2 | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Mueller, C.W, Sadian, Y, Tafur, L. | 登録日 | 2019-05-28 | 公開日 | 2019-12-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular insight into RNA polymerase I promoter recognition and promoter melting. Nat Commun, 10, 2019
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1TRR
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7RSS
| Kod-RI incorporating DNA, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
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8F1J
| SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1K
| SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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6GYM
| Structure of a yeast closed complex with distorted DNA (CCdist) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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4CS5
| Crystal Structure of PCNA from Litopenaeus vannamei | 分子名称: | PROLIFERATING CELL NUCLEAR ANTIGEN | 著者 | Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R. | 登録日 | 2014-03-04 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box. Plos One, 9, 2014
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6WMR
| F. tularensis RNAPs70-(MglA-SspA)-iglA DNA complex | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | 登録日 | 2020-04-21 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
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4WLW
| CRYSTAL STRUCTURE OF THE AG(I) (ACTIVATOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA | 分子名称: | DNA NON-TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP *DTP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DGP*DCP*DTP*DGP*DGP*DAP *DAP*DGP*DGP*DTP*DC)-3, DNA TEMPLATE STRAND (5-D(*DGP*DAP*DCP*DCP*DTP *DTP*DCP*DCP*DAP*DGP*DCP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DAP *DGP*DGP*DTP*DC)-3, HTH-type transcriptional regulator CueR, ... | 著者 | Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. | 登録日 | 2014-10-08 | 公開日 | 2015-09-02 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
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1CZ0
| INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION | 分子名称: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SODIUM ION, ... | 著者 | Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L. | 登録日 | 1999-08-31 | 公開日 | 1999-11-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel endonuclease mechanism directly visualized for I-PpoI. Nat.Struct.Biol., 6, 1999
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6GYL
| Structure of a yeast closed complex with distorted DNA (core CCdist) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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7T02
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7NVT
| RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVU
| RNA polymerase II core pre-initiation complex with open promoter DNA | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVS
| RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2021-03-16 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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5XFR
| Ternary complex of MTF2, DNA and histone | 分子名称: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... | 著者 | Wang, Z, Li, H. | 登録日 | 2017-04-11 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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