PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

---

6OQQ	Legionella pneumophila SidJ/Saccharomyces cerevisiae calmodulin complex 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Tomchick, D.R, Tagliabracci, V.S, Black, M, Osinski, A. 登録日 2019-04-28 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases. Science, 364, 2019
1BJR	COMPLEX FORMED BETWEEN PROTEOLYTICALLY GENERATED LACTOFERRIN FRAGMENT AND PROTEINASE K 分子名称: CALCIUM ION, LACTOFERRIN, PROTEINASE K 著者 Singh, T.P, Sharma, S, Karthikeyan, S, Betzel, C, Bhatia, K.L. 登録日 1998-06-27 公開日 1998-11-04 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K. Proteins, 33, 1998
8SEM	Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni 分子名称: TRPV1 inhibitory peptide Tst2 著者 Elnahriry, K.A, Wai, D.C.C, Norton, R.S. 登録日 2023-04-10 公開日 2023-09-27 実験手法 SOLUTION NMR 主引用文献 Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni. Biochim Biophys Acta Proteins Proteom, 1872, 2023
8CXO	Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment 分子名称: CHOLESTEROL, Smoothened homolog, GlgA glycogen synthase chimera 著者 Zhang, K, Wu, H, Hoppe, N, Manglik, A, Cheng, Y. 登録日 2022-05-22 公開日 2022-08-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Nat Commun, 13, 2022
8DGF	Avs4 bound to phage PhiV-1 portal 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding protein Avs4, MAGNESIUM ION, ... 著者 Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F. 登録日 2022-06-23 公開日 2022-08-03 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Prokaryotic innate immunity through pattern recognition of conserved viral proteins. Science, 377, 2022
8DGC	Avs3 bound to phage PhiV-1 terminase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SeAvs3, ... 著者 Wilkinson, M.E, Gao, L, Strecker, J, Makarova, K.S, Macrae, R.K, Koonin, E.V, Zhang, F. 登録日 2022-06-23 公開日 2022-08-03 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Prokaryotic innate immunity through pattern recognition of conserved viral proteins. Science, 377, 2022
8CW9	Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ... 著者 Hsieh, C.-L, McLellan, J.S. 登録日 2022-05-18 公開日 2022-08-10 最終更新日 2023-02-22 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein. Immunity, 55, 2022
1WYI	human triosephosphate isomerase of new crystal form 分子名称: Triosephosphate isomerase 著者 Kinoshita, T. 登録日 2005-02-14 公開日 2005-04-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method. Acta Crystallogr.,Sect.F, 61, 2005
5J5H	X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(2-methoxyphenyl)-N4,N4-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(2-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine, Acetylcholine-binding protein, ... 著者 Kaczanowska, K, Harel, M, Camacho Hernandez, A.G, Taylor, P. 登録日 2016-04-02 公開日 2017-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017
6P67	Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ... 著者 Walsh, S.T.R, Kashi, L, Kohnhorst, C.L. 登録日 2019-06-03 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia, 34, 2020
5J5I	X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with 4-(2-amino-6-{bis[(pyridin-2-yl)methyl]amino}pyrimidin-4-yl)phenol 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-amino-6-{bis[(pyridin-2-yl)methyl]amino}pyrimidin-4-yl)phenol, Acetylcholine-binding protein, ... 著者 Kaczanowska, K, Harel, M, Camacho Hernandez, G.A, Taylor, P. 登録日 2016-04-02 公開日 2017-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.326 Å) 主引用文献 Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017
5J81	Crystal structure of Glycoprotein C from Puumala virus in the post-fusion conformation (pH 6.0) 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ACETATE ION, Envelopment polyprotein, ... 著者 Willensky, S, Dessau, M. 登録日 2016-04-07 公開日 2016-10-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation. Plos Pathog., 12, 2016
1BMB	GRB2-SH2 DOMAIN IN COMPLEX WITH KPFY*VNVEF (PKF270-974) 分子名称: PROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2), PROTEIN (PKF270-974) 著者 Rondeau, J.M, Zurini, M. 登録日 1998-07-23 公開日 1998-07-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1). J.Med.Chem., 42, 1999
2V8L	Carbohydrate-binding of the starch binding domain of Rhizopus oryzae glucoamylase in complex with beta-cyclodextrin and maltoheptaose 分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), GLUCOAMYLASE A, ZINC ION 著者 Tung, J.-Y, Liu, Y.-Y, Sun, Y.-J. 登録日 2007-08-09 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of the Starch-Binding Domain from Rhizopus Oryzae Glucoamylase Reveal a Polysaccharide-Binding Path. Biochem.J., 416, 2008
6PMO	Co-crystal structure of the Geobacillus kaustophilus glyQ T-box riboswitch discriminator domain in complex with tRNA-Gly 分子名称: IRIDIUM ION, MAGNESIUM ION, T-box riboswitch discriminator, ... 著者 Li, S, Zhang, J. 登録日 2019-07-02 公開日 2019-11-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.65703368 Å) 主引用文献 Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nat.Struct.Mol.Biol., 26, 2019
5J5G	X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with 6-(4-methoxyphenyl)-N4,N4-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(4-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine, Acetylcholine-binding protein, ... 著者 Kaczanowska, K, Harel, M, Camacho Hernandez, A.G, Taylor, P. 登録日 2016-04-02 公開日 2017-03-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.036 Å) 主引用文献 Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017
6PNN	Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)-N-methylsulfamoyl)phenyl)acetamide 分子名称: 2-chloro-N-{4-chloro-3-[(2-methoxyethyl)(methyl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ... 著者 Oakley, A.J. 登録日 2019-07-02 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors. J.Med.Chem., 63, 2020
1BM2	GRB2-SH2 DOMAIN IN COMPLEX WITH CYCLO-[N-ALPHA-ACETYL-L-THI ALYSYL-O-PHOSPHOTYROSYL-VALYL-ASPARAGYL-VALYL-PROLYL] (PKF273-791) 分子名称: PROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2), PROTEIN (PKF273-791) 著者 Rondeau, J.M, Zurini, M. 登録日 1998-07-27 公開日 1998-08-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1). J.Med.Chem., 42, 1999
6P3T	Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT449 分子名称: AMMONIUM ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2019-05-24 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis. Acs Infect Dis., 5, 2019
5J9H	Crystal structure of Glycoprotein C from Puumala virus in the post-fusion conformation (pH 8.0) 分子名称: Envelopment polyprotein, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Willensky, S, Dessau, M. 登録日 2016-04-10 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation. Plos Pathog., 12, 2016
7Q5F	Crystal structure of F2F-2020216-01X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. 分子名称: (S)-1-(2-(2,4-dichlorophenoxy)acetyl)-N-((S)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)-4-(phenethylamino)butan-2-yl)pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, 3C-like proteinase, ... 著者 Costanzi, E, Demitri, N, Storici, P. 登録日 2021-11-03 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Easy access to alpha-ketoamides as SARS-CoV-2 and MERS M pro inhibitors via the PADAM oxidation route. Eur.J.Med.Chem., 244, 2022
7Q5E	Crystal structure of F2F-2020209-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. 分子名称: 3C-like proteinase, CHLORIDE ION, SODIUM ION, ... 著者 Costanzi, E, Demitri, N, Storici, P. 登録日 2021-11-03 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Easy access to alpha-ketoamides as SARS-CoV-2 and MERS M pro inhibitors via the PADAM oxidation route. Eur.J.Med.Chem., 244, 2022
1BP4	USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES. 分子名称: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, PAPAIN 著者 Lalonde, J.M, Zhao, B, Smith, W.W, Janson, C.A, Desjarlais, R.L, Tomaszek, T.A, Carr, T.J, Thompson, S.K, Yamashita, D.S, Veber, D.F, Abdel-Mequid, S.S. 登録日 1998-08-12 公開日 1999-08-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites. J.Med.Chem., 41, 1998
7PQH	Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains). 分子名称: Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8 著者 Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R. 登録日 2021-09-17 公開日 2023-01-18 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 EGOC inhibits TOROID polymerization by structurally activating TORC1. Nat.Struct.Mol.Biol., 30, 2023
5J5F	X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with N4,N4-bis[(pyridin-2-yl)methyl]-6-(thiophen-3-yl)pyrimidine-2,4-diamine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, DIMETHYL SULFOXIDE, ... 著者 Kaczanowska, K, Camacho Hernandez, G.A, Harel, M, Taylor, P. 登録日 2016-04-02 公開日 2017-03-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. J. Am. Chem. Soc., 139, 2017

<347348349350351352353354355356357358359360361362>