5J5H

X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(2-methoxyphenyl)-N4,N4-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine

Summary for 5J5H

• Entry DOI: 10.2210/pdb5j5h/pdb
• Related: 4QAA 4QAB 4QAC 5J5F 5J5G 5J5I
• Descriptor: Acetylcholine-binding protein, 6-(2-methoxyphenyl)-N~4~,N~4~-bis[(pyridin-2-yl)methyl]pyrimidine-2,4-diamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: acetylcholine-binding protein
• Biological source: Lymnaea stagnalis (Great pond snail)
• Cellular location: Secreted: P58154
• Total number of polymer chains: 10
• Total formula weight: 255836.32

Authors

Kaczanowska, K.,Harel, M.,Camacho Hernandez, A.G.,Taylor, P. (deposition date: 2016-04-02, release date: 2017-03-08, Last modification date: 2020-07-29)

• Primary citation: Kaczanowska, K.,Camacho Hernandez, G.A.,Bendiks, L.,Kohs, L.,Cornejo-Bravo, J.M.,Harel, M.,Finn, M.G.,Taylor, P.; Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.; J. Am. Chem. Soc., 139:3676-3684, 2017; PubMed: 28221788; DOI: 10.1021/jacs.6b10746

Experimental method

X-RAY DIFFRACTION (2.7 Å)