8CW9
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
Summary for 8CW9
Entry DOI | 10.2210/pdb8cw9/pdb |
EMDB information | 27024 |
Descriptor | Fusion glycoprotein F0, MPE8 light chain, ADI-61026 heavy, ... (6 entities in total) |
Functional Keywords | site 0 neutralizing antibody, prefusion-stabilized hmpv f protein, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human metapneumovirus More |
Total number of polymer chains | 15 |
Total formula weight | 541479.03 |
Authors | Hsieh, C.-L.,McLellan, J.S. (deposition date: 2022-05-18, release date: 2022-08-10, Last modification date: 2023-02-22) |
Primary citation | Rappazzo, C.G.,Hsieh, C.L.,Rush, S.A.,Esterman, E.S.,Delgado, T.,Geoghegan, J.C.,Wec, A.Z.,Sakharkar, M.,Mas, V.,McLellan, J.S.,Walker, L.M. Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein. Immunity, 55:1710-1724.e8, 2022 Cited by PubMed: 35944529DOI: 10.1016/j.immuni.2022.07.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.46 Å) |
Structure validation
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