1HFD
| HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM | 分子名称: | COMPLEMENT FACTOR D | 著者 | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | 登録日 | 1998-06-18 | 公開日 | 1999-06-22 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
|
|
3USN
| STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE THIADIAZOLE INHIBITOR IPNU-107859, NMR, 1 STRUCTURE | 分子名称: | 2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YL)-UREIDO]-N-METHYL-3-PHENYL-PROPIONAMIDE, CALCIUM ION, STROMELYSIN-1, ... | 著者 | Stockman, B.J. | 登録日 | 1998-06-18 | 公開日 | 1999-01-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of stromelysin complexed to thiadiazole inhibitors. Protein Sci., 7, 1998
|
|
1OSZ
| MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN (L4V) MUTANT OF THE VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN | 分子名称: | BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN | 著者 | Ghendler, Y, Teng, M.-K, Liu, J.-H, Witte, T, Liu, J, Kim, K.S, Kern, P, Chang, H.-C, Wang, J.-H, Reinherz, E.L. | 登録日 | 1998-06-18 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
2CRX
| |
2TSR
| THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | 登録日 | 1998-06-19 | 公開日 | 1999-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
|
|
1BIS
| HIV-1 INTEGRASE CORE DOMAIN | 分子名称: | HIV-1 INTEGRASE | 著者 | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | 登録日 | 1998-06-19 | 公開日 | 1998-08-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
1RTS
| THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | 登録日 | 1998-06-19 | 公開日 | 1999-02-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. Biochemistry, 38, 1999
|
|
1BIW
| DESIGN AND SYNTHESIS OF CONFORMATIONALLY-CONSTRAINED MMP INHIBITORS | 分子名称: | CALCIUM ION, N1-HYDROXY-2-(3-HYDROXY-PROPYL)-3-ISOBUTYL-N4-[1-(2-METHOXY-ETHYL)-2-OXO-AZEPAN-3-YL]-SUCCINAMIDE, PROTEIN (STROMELYSIN-1 COMPLEX), ... | 著者 | Natchus, M.G, Cheng, M, Wahl, C.T, Pikul, S, Almstead, N.G, Bradley, R.S, Taiwo, Y.O, Mieling, G.E, Dunaway, C.M, Snider, C.E, McIver, J.M, Barnett, B.L, McPhail, S.J, Anastasio, M.B, De, B. | 登録日 | 1998-06-19 | 公開日 | 1999-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design and synthesis of conformationally-constrained MMP inhibitors. Bioorg.Med.Chem.Lett., 8, 1998
|
|
1BIX
| THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES | 分子名称: | AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION | 著者 | Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S. | 登録日 | 1998-06-19 | 公開日 | 1999-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J., 16, 1997
|
|
1BIU
| HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++ | 分子名称: | HIV-1 INTEGRASE, MAGNESIUM ION | 著者 | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | 登録日 | 1998-06-19 | 公開日 | 1998-08-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
3CRX
| |
1BI2
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | 分子名称: | DIPHTHERIA TOXIN REPRESSOR | 著者 | Pohl, E, Hol, W.G.J. | 登録日 | 1998-06-21 | 公開日 | 1999-06-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
|
|
1BI0
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | 分子名称: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | 著者 | Pohl, E, Hol, W.G. | 登録日 | 1998-06-21 | 公開日 | 1999-07-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
|
|
1BI1
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | 分子名称: | DIPHTHERIA TOXIN REPRESSOR | 著者 | Pohl, E, Hol, W.G.J. | 登録日 | 1998-06-21 | 公開日 | 1999-06-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
|
|
1BI3
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | 分子名称: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | 著者 | Pohl, E, Hol, W.G.J. | 登録日 | 1998-06-21 | 公開日 | 1999-06-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
|
|
1BIZ
| HIV-1 INTEGRASE CORE DOMAIN | 分子名称: | CACODYLATE ION, HIV-1 INTEGRASE | 著者 | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | 登録日 | 1998-06-21 | 公開日 | 1998-08-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
1CN2
| SOLUTION STRUCTURE OF TOXIN 2 FROM CENTRUROIDES NOXIUS HOFFMANN, A BETA SCORPION NEUROTOXIN ACTING ON SODIUM CHANNELS, NMR, 15 STRUCTURES | 分子名称: | TOXIN 2 | 著者 | Pintar, A, Possani, L.D, Delepierre, M. | 登録日 | 1998-06-21 | 公開日 | 1999-01-13 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels. J.Mol.Biol., 287, 1999
|
|
1PIN
| PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ... | 著者 | Noel, J.P, Ranganathan, R, Hunter, T. | 登録日 | 1998-06-21 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell(Cambridge,Mass.), 89, 1997
|
|
1BIY
| STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN | 分子名称: | CARBONATE ION, FE (III) ION, LACTOFERRIN | 著者 | Karthikeyan, S, Yadav, S, Singh, T.P. | 登録日 | 1998-06-21 | 公開日 | 1999-01-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Structure of buffalo lactoferrin at 3.3 A resolution at 277 K. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1BI7
| MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | 分子名称: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 1998-06-22 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
|
|
1BI5
| CHALCONE SYNTHASE FROM ALFALFA | 分子名称: | CHALCONE SYNTHASE | 著者 | Ferrer, J.L, Jez, J.M, Bowman, M.E, Dixon, R.A, Noel, J.P. | 登録日 | 1998-06-22 | 公開日 | 1999-06-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat.Struct.Biol., 6, 1999
|
|
1BI8
| MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | 分子名称: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | 著者 | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 1998-06-22 | 公開日 | 1999-01-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
|
|
1BI4
| CATALYTIC DOMAIN OF HIV-1 INTEGRASE | 分子名称: | INTEGRASE | 著者 | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | 登録日 | 1998-06-22 | 公開日 | 1998-11-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
|
|
2TDX
| DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL | 分子名称: | DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | 著者 | White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R. | 登録日 | 1998-06-22 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature, 394, 1998
|
|
1FZD
| STRUCTURE OF RECOMBINANT ALPHAEC DOMAIN FROM HUMAN FIBRINOGEN-420 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Spraggon, G, Applegate, D, Everse, S.J, Zhang, J.-Z, Veerapandian, L, Redman, C, Doolittle, R.F, Grieninger, G. | 登録日 | 1998-06-22 | 公開日 | 1998-08-19 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a recombinant alphaEC domain from human fibrinogen-420. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|