PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

---

6OEP	Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2025-05-21 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6PST	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
5UQ9	Crystal structure of 6-phosphogluconate dehydrogenase with ((4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl dihydrogen phosphate 分子名称: 6-phosphogluconate dehydrogenase, decarboxylating, [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl dihydrogen phosphate 著者 Leonard, P.G. 登録日 2017-02-07 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Rep, 26, 2019
5IPM	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
6PSV	Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6WEU	Crystal structures of human E-NPP 1: bound to adenosine-5'-thio-monophosphate 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Peat, T.S, Dennis, M, Newman, J. 登録日 2020-04-03 公開日 2020-09-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76, 2020
6WFJ	Crystal structures of human E-NPP 1: apo 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Peat, T.S, Dennis, M, Newman, J. 登録日 2020-04-03 公開日 2020-09-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76, 2020
6N01	Structure of apo AztD from Citrobacter koseri 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AztD Protein, ... 著者 Yukl, E.T, Neupane, D.P. 登録日 2018-11-06 公開日 2019-09-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structures of AztD provide mechanistic insights into direct zinc transfer between proteins. Commun Biol, 2, 2019
5X07	Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site 分子名称: DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Hepatocyte nuclear factor 3-beta 著者 Li, J, Guo, M, Zhou, Z, Jiang, L, Chen, X, Qu, L, Wu, D, Chen, Z, Chen, L, Chen, Y. 登録日 2017-01-20 公開日 2017-08-16 最終更新日 2025-04-09 実験手法 X-RAY DIFFRACTION (2.796 Å) 主引用文献 Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site Biochemistry, 56, 2017
7QGG	Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Pulk, A, Kipper, K, Mansour, A. 登録日 2021-12-08 公開日 2022-10-26 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state. J.Mol.Biol., 434, 2022
6WEV	Crystal structures of human E-NPP 1: bound to N-{[1-(6,7-dimethoxy-5,8-dihydroquinazolin-4-yl)piperidin-4-yl]methyl}sulfuric diamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Peat, T.S, Dennis, M, Newman, J. 登録日 2020-04-03 公開日 2020-09-09 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76, 2020
6P1K	Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-05-20 公開日 2020-02-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6N5C	Crystal structure of the catalytic domain of PPIP5K2 in complex with AMPPNP and 5-PCF2Am-InsP5 分子名称: (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Wang, H, Shears, S.B, Riley, A, Potter, B. 登録日 2018-11-21 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Synthesis of an alpha-phosphono-alpha , alpha-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7. Medchemcomm, 10, 2019
6P19	Q21 transcription antitermination complex: loaded complex 分子名称: DNA (123-MER) fragment carrying phage-21 pR' promoter, pause element, and transcribed region, ... 著者 Yin, Z, Ebright, R.H. 登録日 2019-05-19 公開日 2019-06-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
5IPN	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (4.61 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5N4L	Rat ceruloplasmin trigonal form 分子名称: CALCIUM ION, COPPER (II) ION, Ceruloplasmin, ... 著者 Samygina, V.R, Sokolov, A.V, Bourenkov, G, Vasilyev, V.B. 登録日 2017-02-11 公開日 2017-12-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Rat ceruloplasmin: a new labile copper binding site and zinc/copper mosaic. Metallomics, 9, 2017
5HLZ	Structure of Pro-Activin A Complex at 2.85 A resolution 分子名称: Inhibin beta A chain 著者 Wang, X, Fischer, G, Hyvonen, M. 登録日 2016-01-15 公開日 2016-07-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 Structure and activation of pro-activin A. Nat Commun, 7, 2016
6NPL	Cryo-EM structure of NKCC1 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... 著者 Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. 登録日 2019-01-17 公開日 2019-07-31 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
5WDY	Crystal structure of WNK1 in complex with 1-cyclohexyl-N-({6-fluoro-1-[2-(3-methoxyphenyl)pyridin-4-yl]-1H-indol-3-yl}methyl)methanamine (compound 6) 分子名称: 1-cyclohexyl-N-({6-fluoro-1-[2-(3-methoxyphenyl)pyridin-4-yl]-1H-indol-3-yl}methyl)methanamine, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Xie, X, Kohls, D. 登録日 2017-07-06 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.458 Å) 主引用文献 Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J. Med. Chem., 60, 2017
5V9G	Structure of the H477R variant of rat cytosolic PEPCK in complex with oxalate and GTP. 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... 著者 Holyoak, T, Cui, D.S. 登録日 2017-03-23 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
6N58	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
5UNJ	Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100 分子名称: (1R,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, Nuclear receptor subfamily 5 group A member 2, Peroxisome proliferator-activated gamma coactivator 1-alpha 著者 Mays, S.G, Ortlund, E.A. 登録日 2017-01-31 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.959 Å) 主引用文献 Structure and Dynamics of the Liver Receptor Homolog 1-PGC1 alpha Complex. Mol. Pharmacol., 92, 2017
6ON4	Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid 分子名称: HTH-type transcriptional repressor NanR, N-acetyl-beta-neuraminic acid, ZINC ION, ... 著者 Horne, C.R, Panjikar, S, North, R.A, Dobson, R.C.J. 登録日 2019-04-19 公開日 2020-07-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Control of the Escherichia coli sialoregulon by transcriptional repressor NanR. J. Bacteriol., 195, 2013
6NPH	Structure of NKCC1 TM domain 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... 著者 Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. 登録日 2019-01-17 公開日 2019-07-31 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
5WZZ	The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation 分子名称: Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION 著者 Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. 登録日 2017-01-19 公開日 2017-08-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation Genes Dev., 31, 2017

<336337338339340341342343344345346347348349350351>