PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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7S8A	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE, CUBIC CRYSTAL FORM 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-2-microglobulin, ... 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-17 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8VDY	Crystal Structure of Delta 114-117 D-Dopachrome Tautomerase (D-DT) 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-18 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8XAX	Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ... 著者 An, Q, Deng, Z. 登録日 2023-12-05 公開日 2024-06-05 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 2024
8VG8	Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) Bound to 4CPPC 分子名称: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-23 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
7S7F	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PHOSPHOPEPTIDE 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-15 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8YBE	Cryo-EM structure of Maltose Binding Protein 分子名称: Maltose/maltodextrin-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Yoo, Y, Park, K, Kim, H. 登録日 2024-02-13 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Atomic resolution structure of MBP using Cryo-EM To Be Published
7S7E	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PEPTIDE 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-15 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8W8Q	Cryo-EM structure of the GPR101-Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Sun, J.P, Gao, N, Yu, X, Wang, G.P, Yang, F, Wang, J.Y, Yang, Z, Guan, Y. 登録日 2023-09-04 公開日 2024-01-03 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nat.Chem.Biol., 20, 2024
7S79	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC PHOSPHONO-MLL PEPTIDE ANALOG 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-15 公開日 2022-11-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8VFO	Crystal Structure of L117G Variant of D-Dopachrome Tautomerase (D-DT) 分子名称: CITRIC ACID, D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8U1C	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-400 heavy chain, ... 著者 Ferguson, J.A, Oeverdieck, S, Ward, A.B. 登録日 2023-08-31 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
7S8J	PHOSPHOPEPTIDE-SPECIFIC LC13 TCR, ORTHORHOMBIC CRYSTAL FORM 分子名称: CHLORIDE ION, TRAV27_LC13 TCR ALPHA CHAIN, TRBV27_LC13 TCR BETA CHAIN 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-17 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8VFL	Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 290K 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8U4W	The crystal structure of a helical domain deleted PARP1 in complex with isoindolinone based inhibitor. 分子名称: (4M)-4-(2-{4-[(3S)-1-acetylpiperidine-3-carbonyl]piperazine-1-carbonyl}-1-benzofuran-7-yl)-1H-isoindol-1-one, Poly [ADP-ribose] polymerase 1, processed C-terminus 著者 Marcotte, D.J. 登録日 2023-09-11 公開日 2024-03-27 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Discovery of Potent Isoindolinone Inhibitors that Target an Active Conformation of PARP1 Using DNA-Encoded Libraries. Chemmedchem, 19, 2024
7S7D	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC SULFO-MLL PEPTIDE ANALOG 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-15 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8VG7	Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-23 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
7S8E	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE AND BOUND GLYCEROL 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Patskovsky, Y, Nyovanie, S, Patskovska, L, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-17 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
7E8I	Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin 分子名称: BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ... 著者 Dai, Y, Dai, L, Zhou, Z. 登録日 2021-03-01 公開日 2021-06-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin. Mol.Cell, 81, 2021
7RZJ	CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... 著者 Patskovsky, Y, Patskovska, L, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-08-27 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
8VFN	Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 310K 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VFW	Crystal Structure of V113N D-Dopachrome Tautomerase (D-DT) 分子名称: CITRIC ACID, D-dopachrome decarboxylase 著者 Parkins, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-22 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
7S8F	STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE AND BOUND GLYCEROL 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Patskovsky, Y, Nyovanie, S, Patskovska, L, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M. 登録日 2021-09-17 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nat Commun, 14, 2023
7K80	KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ... 著者 MacLachlan, B.J, Rossjohn, J, Vivian, J.P. 登録日 2020-09-24 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. J Immunol., 206, 2021
8W8S	Cryo-EM structure of the AA14-bound GPR101 complex 分子名称: 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Probable G-protein coupled receptor 101 著者 Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. 登録日 2023-09-04 公開日 2024-01-03 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nat.Chem.Biol., 20, 2024
8W8R	Cryo-EM structure of the AA-14-bound GPR101-Gs complex 分子名称: 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. 登録日 2023-09-04 公開日 2024-01-03 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nat.Chem.Biol., 20, 2024

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