8VFO
Crystal Structure of L117G Variant of D-Dopachrome Tautomerase (D-DT)
Summary for 8VFO
| Entry DOI | 10.2210/pdb8vfo/pdb |
| Descriptor | D-dopachrome decarboxylase, CITRIC ACID (3 entities in total) |
| Functional Keywords | truncation, enzyme, cytokine, isomerase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 12729.55 |
| Authors | Parkins, A.,Pilien, A.,Thompson, M.C.,Pantouris, G. (deposition date: 2023-12-21, release date: 2024-05-01, Last modification date: 2024-05-22) |
| Primary citation | Parkins, A.,Pilien, A.V.R.,Wolff, A.M.,Argueta, C.,Vargas, J.,Sadeghi, S.,Franz, A.H.,Thompson, M.C.,Pantouris, G. The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67:7359-7372, 2024 Cited by PubMed: 38670943DOI: 10.1021/acs.jmedchem.4c00177 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
Download full validation report
